These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
395 related articles for article (PubMed ID: 24157870)
1. O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas. Fan CH; Liu WL; Cao H; Wen C; Chen L; Jiang G Cell Death Dis; 2013 Oct; 4(10):e876. PubMed ID: 24157870 [TBL] [Abstract][Full Text] [Related]
2. Chemoresistance to temozolomide in human glioma cell line U251 is associated with increased activity of O6-methylguanine-DNA methyltransferase and can be overcome by metronomic temozolomide regimen. Pan Q; Yang XJ; Wang HM; Dong XT; Wang W; Li Y; Li JM Cell Biochem Biophys; 2012 Jan; 62(1):185-91. PubMed ID: 21892781 [TBL] [Abstract][Full Text] [Related]
3. Strategies to improve the killing of tumors using temozolomide: targeting the DNA repair protein MGMT. Jiang G; Li LT; Xin Y; Zhang L; Liu YQ; Zheng JN Curr Med Chem; 2012; 19(23):3886-92. PubMed ID: 22788764 [TBL] [Abstract][Full Text] [Related]
4. Progression of O⁶-methylguanine-DNA methyltransferase and temozolomide resistance in cancer research. Jiang G; Jiang AJ; Xin Y; Li LT; Cheng Q; Zheng JN Mol Biol Rep; 2014 Oct; 41(10):6659-65. PubMed ID: 24990698 [TBL] [Abstract][Full Text] [Related]
5. Correlations of MGMT genetic polymorphisms with temozolomide resistance and prognosis of patients with malignant gliomas: a population-based study in China. Wang HW; Xu ZK; Song Y; Liu YG Cancer Gene Ther; 2017 May; 24(5):215-220. PubMed ID: 28409559 [TBL] [Abstract][Full Text] [Related]
6. The L84F polymorphic variant of human O6-methylguanine-DNA methyltransferase alters stability in U87MG glioma cells but not temozolomide sensitivity. Remington M; Chtchetinin J; Ancheta K; Nghiemphu PL; Cloughesy T; Lai A Neuro Oncol; 2009 Feb; 11(1):22-32. PubMed ID: 18812520 [TBL] [Abstract][Full Text] [Related]
7. miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectely. Xiao S; Yang Z; Qiu X; Lv R; Liu J; Wu M; Liao Y; Liu Q Oncotarget; 2016 Aug; 7(31):50229-50238. PubMed ID: 27384876 [TBL] [Abstract][Full Text] [Related]
8. Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas. Minea RO; Duc TC; Swenson SD; Cho HY; Huang M; Hartman H; Hofman FM; Schönthal AH; Chen TC PLoS One; 2020; 15(9):e0238238. PubMed ID: 32881880 [TBL] [Abstract][Full Text] [Related]
9. The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma. Xu H; Zhang Y; Li L; Ren Y; Qian F; Wang L; Ma H; Quan A; Liu H; Yu R Drug Deliv; 2023 Dec; 30(1):1-13. PubMed ID: 36579448 [TBL] [Abstract][Full Text] [Related]
10. β-catenin contributes to cordycepin-induced MGMT inhibition and reduction of temozolomide resistance in glioma cells by increasing intracellular reactive oxygen species. Bi Y; Li H; Yi D; Bai Y; Zhong S; Liu Q; Chen Y; Zhao G Cancer Lett; 2018 Oct; 435():66-79. PubMed ID: 30081068 [TBL] [Abstract][Full Text] [Related]
11. Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine. Roos WP; Batista LF; Naumann SC; Wick W; Weller M; Menck CF; Kaina B Oncogene; 2007 Jan; 26(2):186-97. PubMed ID: 16819506 [TBL] [Abstract][Full Text] [Related]
12. A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system. Alvino E; Castiglia D; Caporali S; Pepponi R; Caporaso P; Lacal PM; Marra G; Fischer F; Zambruno G; Bonmassar E; Jiricny J; D'Atri S Int J Oncol; 2006 Oct; 29(4):785-97. PubMed ID: 16964376 [TBL] [Abstract][Full Text] [Related]
13. Methionine restriction of glioma does not induce MGMT and greatly improves temozolomide efficacy in an orthotopic nude-mouse model: A potential curable approach to a clinically-incurable disease. Kubota Y; Aoki Y; Masaki N; Obara K; Hamada K; Han Q; Bouvet M; Tsunoda T; Hoffman RM Biochem Biophys Res Commun; 2024 Feb; 695():149418. PubMed ID: 38176171 [TBL] [Abstract][Full Text] [Related]
14. 20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma. Chen Z; Wei X; Shen L; Zhu H; Zheng X Cancer Sci; 2019 Jan; 110(1):389-400. PubMed ID: 30431207 [TBL] [Abstract][Full Text] [Related]
15. Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT. Fukushima T; Takeshima H; Kataoka H Anticancer Res; 2009 Nov; 29(11):4845-54. PubMed ID: 20032445 [TBL] [Abstract][Full Text] [Related]
16. dCas9/CRISPR-based methylation of O-6-methylguanine-DNA methyltransferase enhances chemosensitivity to temozolomide in malignant glioma. Zapanta Rinonos S; Li T; Pianka ST; Prins TJ; Eldred BSC; Kevan BM; Liau LM; Nghiemphu PL; Cloughesy TF; Lai A J Neurooncol; 2024 Jan; 166(1):129-142. PubMed ID: 38224404 [TBL] [Abstract][Full Text] [Related]
17. Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine. Kokkinakis DM; Ahmed MM; Chendil D; Moschel RC; Pegg AE Clin Cancer Res; 2003 Sep; 9(10 Pt 1):3801-7. PubMed ID: 14506174 [TBL] [Abstract][Full Text] [Related]
18. O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells. Hermisson M; Klumpp A; Wick W; Wischhusen J; Nagel G; Roos W; Kaina B; Weller M J Neurochem; 2006 Feb; 96(3):766-76. PubMed ID: 16405512 [TBL] [Abstract][Full Text] [Related]
19. Enhanced anti-tumor effect of zoledronic acid combined with temozolomide against human malignant glioma cell expressing O6-methylguanine DNA methyltransferase. Fukai J; Koizumi F; Nakao N PLoS One; 2014; 9(8):e104538. PubMed ID: 25111384 [TBL] [Abstract][Full Text] [Related]