BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 24168270)

  • 1. Orthogonal assembly of a designed ankyrin repeat protein-cytotoxin conjugate with a clickable serum albumin module for half-life extension.
    Simon M; Frey R; Zangemeister-Wittke U; Plückthun A
    Bioconjug Chem; 2013 Nov; 24(11):1955-66. PubMed ID: 24168270
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Facile double-functionalization of designed ankyrin repeat proteins using click and thiol chemistries.
    Simon M; Zangemeister-Wittke U; Plückthun A
    Bioconjug Chem; 2012 Feb; 23(2):279-86. PubMed ID: 22188139
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increasing the antitumor effect of an EpCAM-targeting fusion toxin by facile click PEGylation.
    Simon M; Stefan N; Borsig L; Plückthun A; Zangemeister-Wittke U
    Mol Cancer Ther; 2014 Feb; 13(2):375-85. PubMed ID: 24184633
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel prodrug-like fusion toxin with protease-sensitive bioorthogonal PEGylation for tumor targeting.
    Stefan N; Zimmermann M; Simon M; Zangemeister-Wittke U; Plückthun A
    Bioconjug Chem; 2014 Dec; 25(12):2144-56. PubMed ID: 25350699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Half-life extension using serum albumin-binding DARPin® domains.
    Steiner D; Merz FW; Sonderegger I; Gulotti-Georgieva M; Villemagne D; Phillips DJ; Forrer P; Stumpp MT; Zitt C; Binz HK
    Protein Eng Des Sel; 2017 Sep; 30(9):583-591. PubMed ID: 29088432
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DARPins: a true alternative to antibodies.
    Stumpp MT; Amstutz P
    Curr Opin Drug Discov Devel; 2007 Mar; 10(2):153-9. PubMed ID: 17436550
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Preparation and characterization of albumin conjugates of a truncated peptide YY analogue for half-life extension.
    Ehrlich GK; Michel H; Truitt T; Riboulet W; Pop-Damkov P; Goelzer P; Hainzl D; Qureshi F; Lueckel B; Danho W; Conde-Knape K; Konkar A
    Bioconjug Chem; 2013 Dec; 24(12):2015-24. PubMed ID: 24251972
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing.
    Lorenzer C; Streußnig S; Tot E; Winkler AM; Merten H; Brandl F; Sayers EJ; Watson P; Jones AT; Zangemeister-Wittke U; Plückthun A; Winkler J
    Eur J Pharm Biopharm; 2019 Aug; 141():37-50. PubMed ID: 31103742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling.
    Merten H; Brandl F; Zimmermann M; Schaefer JV; Irpinio L; Sand KMK; Nilsen J; Andersen JT; Zangemeister-Wittke U; Plückthun A
    Eur J Pharm Biopharm; 2021 Oct; 167():104-113. PubMed ID: 34303832
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin.
    Yang B; Kim JC; Seong J; Tae G; Kwon I
    Biomater Sci; 2018 Jul; 6(8):2092-2100. PubMed ID: 29881837
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Efficient tumor targeting with high-affinity designed ankyrin repeat proteins: effects of affinity and molecular size.
    Zahnd C; Kawe M; Stumpp MT; de Pasquale C; Tamaskovic R; Nagy-Davidescu G; Dreier B; Schibli R; Binz HK; Waibel R; Plückthun A
    Cancer Res; 2010 Feb; 70(4):1595-605. PubMed ID: 20124480
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Optimizing the anti-tumor efficacy of protein-drug conjugates by engineering the molecular size and half-life.
    Brandl F; Busslinger S; Zangemeister-Wittke U; Plückthun A
    J Control Release; 2020 Nov; 327():186-197. PubMed ID: 32768630
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Improved efficacy of alphavbeta3-targeted albumin conjugates by conjugation of a novel auristatin derivative.
    Temming K; Meyer DL; Zabinski R; Senter PD; Poelstra K; Molema G; Kok RJ
    Mol Pharm; 2007; 4(5):686-94. PubMed ID: 17683157
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Site-specific antibody-drug conjugation through glycoengineering.
    Zhou Q; Stefano JE; Manning C; Kyazike J; Chen B; Gianolio DA; Park A; Busch M; Bird J; Zheng X; Simonds-Mannes H; Kim J; Gregory RC; Miller RJ; Brondyk WH; Dhal PK; Pan CQ
    Bioconjug Chem; 2014 Mar; 25(3):510-20. PubMed ID: 24533768
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preclinical evaluation of EpCAM-binding designed ankyrin repeat proteins (DARPins) as targeting moieties for bimodal near-infrared fluorescence and photoacoustic imaging of cancer.
    Houvast RD; Badr N; March T; de Muynck LDAN; Sier VQ; Schomann T; Bhairosingh S; Baart VM; Peeters JAHM; van Westen GJP; Plückthun A; Burggraaf J; Kuppen PJK; Vahrmeijer AL; Sier CFM
    Eur J Nucl Med Mol Imaging; 2024 Jul; 51(8):2179-2192. PubMed ID: 37642704
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of a radiolabel biochemical nature on tumor-targeting properties of EpCAM-binding engineered scaffold protein DARPin Ec1.
    Deyev SM; Vorobyeva A; Schulga A; Abouzayed A; Günther T; Garousi J; Konovalova E; Ding H; Gräslund T; Orlova A; Tolmachev V
    Int J Biol Macromol; 2020 Feb; 145():216-225. PubMed ID: 31863835
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antibody-Drug Conjugates for Tumor Targeting-Novel Conjugation Chemistries and the Promise of non-IgG Binding Proteins.
    Merten H; Brandl F; Plückthun A; Zangemeister-Wittke U
    Bioconjug Chem; 2015 Nov; 26(11):2176-85. PubMed ID: 26086208
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of amino acid residues of a designed ankyrin repeat protein potentially involved in intermolecular interactions with CD4: analysis by molecular dynamics simulations.
    Nimmanpipug P; Khampa C; Lee VS; Nangola S; Tayapiwatana C
    J Mol Graph Model; 2011 Nov; 31():65-75. PubMed ID: 21962990
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity.
    Doronina SO; Mendelsohn BA; Bovee TD; Cerveny CG; Alley SC; Meyer DL; Oflazoglu E; Toki BE; Sanderson RJ; Zabinski RF; Wahl AF; Senter PD
    Bioconjug Chem; 2006; 17(1):114-24. PubMed ID: 16417259
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stabilizing ionic interactions in a full-consensus ankyrin repeat protein.
    Merz T; Wetzel SK; Firbank S; Plückthun A; Grütter MG; Mittl PR
    J Mol Biol; 2008 Feb; 376(1):232-40. PubMed ID: 18155045
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.