BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 24169826)

  • 1. The Myc-miR-17-92 axis amplifies B-cell receptor signaling via inhibition of ITIM proteins: a novel lymphomagenic feed-forward loop.
    Psathas JN; Doonan PJ; Raman P; Freedman BD; Minn AJ; Thomas-Tikhonenko A
    Blood; 2013 Dec; 122(26):4220-9. PubMed ID: 24169826
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt.
    Juszczynski P; Chen L; O'Donnell E; Polo JM; Ranuncolo SM; Dalla-Favera R; Melnick A; Shipp MA
    Blood; 2009 Dec; 114(26):5315-21. PubMed ID: 19855081
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MYC Protein-positive Diffuse Large B-Cell Lymphoma Features an Activated B-Cell Receptor Signal Pathway.
    Wang WG; Jiang XN; Liu ZB; Zhou XY; Li XQ
    Am J Surg Pathol; 2017 Apr; 41(4):541-549. PubMed ID: 28291124
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma.
    Chen L; Monti S; Juszczynski P; Daley J; Chen W; Witzig TE; Habermann TM; Kutok JL; Shipp MA
    Blood; 2008 Feb; 111(4):2230-7. PubMed ID: 18006696
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Besides an ITIM/SHP-1-dependent pathway, CD22 collaborates with Grb2 and plasma membrane calcium-ATPase in an ITIM/SHP-1-independent pathway of attenuation of Ca2+i signal in B cells.
    Chen J; Wang H; Xu WP; Wei SS; Li HJ; Mei YQ; Li YG; Wang YP
    Oncotarget; 2016 Aug; 7(35):56129-56146. PubMed ID: 27276708
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Swiprosin-1/EFhd2 controls B cell receptor signaling through the assembly of the B cell receptor, Syk, and phospholipase C gamma2 in membrane rafts.
    Kroczek C; Lang C; Brachs S; Grohmann M; Dütting S; Schweizer A; Nitschke L; Feller SM; Jäck HM; Mielenz D
    J Immunol; 2010 Apr; 184(7):3665-76. PubMed ID: 20194721
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas.
    Szydlowski M; Kiliszek P; Sewastianik T; Jablonska E; Bialopiotrowicz E; Gorniak P; Polak A; Markowicz S; Nowak E; Grygorowicz MA; Prochorec-Sobieszek M; Szumera-Cieckiewicz A; Malenda A; Lech-Maranda E; Warzocha K; Juszczynski P
    Blood; 2016 Feb; 127(6):739-48. PubMed ID: 26585955
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies.
    Ortega M; Bhatnagar H; Lin AP; Wang L; Aster JC; Sill H; Aguiar RC
    Leukemia; 2015 Apr; 29(4):968-76. PubMed ID: 25311243
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deregulated Syk inhibits differentiation and induces growth factor-independent proliferation of pre-B cells.
    Wossning T; Herzog S; Köhler F; Meixlsperger S; Kulathu Y; Mittler G; Abe A; Fuchs U; Borkhardt A; Jumaa H
    J Exp Med; 2006 Dec; 203(13):2829-40. PubMed ID: 17130299
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1.
    Otipoby KL; Draves KE; Clark EA
    J Biol Chem; 2001 Nov; 276(47):44315-22. PubMed ID: 11551923
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MiR-17-92 represses PTPROt and PP2A phosphatases and amplifies tonic BCR signaling in DLBCL cells.
    Jablonska E; Gorniak P; Szydlowski M; Sewastianik T; Bialopiotrowicz E; Polak A; Warzocha K; Juszczynski P
    Exp Hematol; 2017 Feb; 46():56-61.e1. PubMed ID: 27720936
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel binding site for Src homology 2-containing protein-tyrosine phosphatase-1 in CD22 activated by B lymphocyte stimulation with antigen.
    Zhu C; Sato M; Yanagisawa T; Fujimoto M; Adachi T; Tsubata T
    J Biol Chem; 2008 Jan; 283(3):1653-1659. PubMed ID: 18024433
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MYC protein dysregulation is driven by BCR-PI3K signalling in diffuse large B-cell lymphoma.
    Wang WG; Liu ZB; Jiang XN; Lee J; Zhou XY; Li XQ
    Histopathology; 2017 Nov; 71(5):778-785. PubMed ID: 28639315
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells.
    Niiro H; Jabbarzadeh-Tabrizi S; Kikushige Y; Shima T; Noda K; Ota S; Tsuzuki H; Inoue Y; Arinobu Y; Iwasaki H; Shimoda S; Baba E; Tsukamoto H; Horiuchi T; Taniyama T; Akashi K
    Blood; 2012 Mar; 119(10):2263-73. PubMed ID: 22262777
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CD22 ligation inhibits downstream B cell receptor signaling and Ca(2+) flux upon activation.
    Sieger N; Fleischer SJ; Mei HE; Reiter K; Shock A; Burmester GR; Daridon C; Dörner T
    Arthritis Rheum; 2013 Mar; 65(3):770-9. PubMed ID: 23233360
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas.
    Chen L; Monti S; Juszczynski P; Ouyang J; Chapuy B; Neuberg D; Doench JG; Bogusz AM; Habermann TM; Dogan A; Witzig TE; Kutok JL; Rodig SJ; Golub T; Shipp MA
    Cancer Cell; 2013 Jun; 23(6):826-38. PubMed ID: 23764004
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling.
    Myklebust JH; Brody J; Kohrt HE; Kolstad A; Czerwinski DK; Wälchli S; Green MR; Trøen G; Liestøl K; Beiske K; Houot R; Delabie J; Alizadeh AA; Irish JM; Levy R
    Blood; 2017 Feb; 129(6):759-770. PubMed ID: 28011673
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development.
    Kulathu Y; Hobeika E; Turchinovich G; Reth M
    EMBO J; 2008 May; 27(9):1333-44. PubMed ID: 18369315
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quantitative immunofluorescence reveals the signature of active B-cell receptor signaling in diffuse large B-cell lymphoma.
    Bogusz AM; Baxter RH; Currie T; Sinha P; Sohani AR; Kutok JL; Rodig SJ
    Clin Cancer Res; 2012 Nov; 18(22):6122-35. PubMed ID: 22966017
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein tyrosine phosphatase receptor-type O truncated (PTPROt) regulates SYK phosphorylation, proximal B-cell-receptor signaling, and cellular proliferation.
    Chen L; Juszczynski P; Takeyama K; Aguiar RC; Shipp MA
    Blood; 2006 Nov; 108(10):3428-33. PubMed ID: 16888096
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.