BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 24172718)

  • 1. Cocktail-substrate approach-based high-throughput assay for evaluation of direct and time-dependent inhibition of multiple cytochrome P450 isoforms.
    Kozakai K; Yamada Y; Oshikata M; Kawase T; Suzuki E; Haramaki Y; Taniguchi H
    Drug Metab Pharmacokinet; 2014; 29(2):198-207. PubMed ID: 24172718
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An in vitro, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS.
    Otten JN; Hingorani GP; Hartley DP; Kragerud SD; Franklin RB
    Drug Metab Lett; 2011 Jan; 5(1):17-24. PubMed ID: 21198441
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reliable high-throughput method for inhibition assay of 8 cytochrome P450 isoforms using cocktail of probe substrates and stable isotope-labeled internal standards.
    Kozakai K; Yamada Y; Oshikata M; Kawase T; Suzuki E; Haramaki Y; Taniguchi H
    Drug Metab Pharmacokinet; 2012; 27(5):520-9. PubMed ID: 22498647
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development and validation of an in vitro, seven-in-one human cytochrome P450 assay for evaluation of both direct and time-dependent inhibition.
    Dahlinger D; Duechting S; Nuecken D; Sydow K; Fuhr U; Frechen S
    J Pharmacol Toxicol Methods; 2016; 77():66-75. PubMed ID: 26528794
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A sensitive and high-throughput LC-MS/MS method for inhibition assay of seven major cytochrome P450s in human liver microsomes using an in vitro cocktail of probe substrates.
    Liu LY; Han YL; Zhu JH; Yu Q; Yang QJ; Lu J; Guo C
    Biomed Chromatogr; 2015 Mar; 29(3):437-44. PubMed ID: 25098274
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of cytochrome P450 inhibition assays using human liver microsomes by a cassette analysis /LC-MS/MS.
    Zambon S; Fontana S; Kajbaf M
    Drug Metab Lett; 2010 Aug; 4(3):120-8. PubMed ID: 20642444
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail
    Valicherla GR; Mishra A; Lenkalapelly S; Jillela B; Francis FM; Rajagopalan L; Srivastava P
    Xenobiotica; 2019 Dec; 49(12):1396-1402. PubMed ID: 30747554
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An improved substrate cocktail for assessing direct inhibition and time-dependent inhibition of multiple cytochrome P450s.
    Chen ZH; Zhang SX; Long N; Lin LS; Chen T; Zhang FP; Lv XQ; Ye PZ; Li N; Zhang KZ
    Acta Pharmacol Sin; 2016 May; 37(5):708-18. PubMed ID: 27063220
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of GC-MS based cytochrome P450 assay for the investigation of multi-herb interaction.
    Oh HA; Lee H; Kim D; Jung BH
    Anal Biochem; 2017 Feb; 519():71-83. PubMed ID: 28007398
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Screening of ten cytochrome P450 enzyme activities with 12 probe substrates in human liver microsomes using cocktail incubation and liquid chromatography-tandem mass spectrometry.
    Kim HJ; Lee H; Ji HK; Lee T; Liu KH
    Biopharm Drug Dispos; 2019 Apr; 40(3-4):101-111. PubMed ID: 30730576
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions.
    Li G; Huang K; Nikolic D; van Breemen RB
    Drug Metab Dispos; 2015 Nov; 43(11):1670-8. PubMed ID: 26285764
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5'-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography-Tandem Mass Spectrometry.
    Lee B; Ji HK; Lee T; Liu KH
    Drug Metab Dispos; 2015 Jul; 43(7):1137-46. PubMed ID: 25904760
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Use of stable isotope labeled probes to facilitate liquid chromatography/mass spectrometry based high-throughput screening of time-dependent CYP inhibitors.
    Dasgupta M; Tang W; Caldwell GW; Yan Z
    Rapid Commun Mass Spectrom; 2010 Aug; 24(15):2177-85. PubMed ID: 20583325
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development and validation of a liquid-chromatography high-resolution tandem mass spectrometry approach for quantification of nine cytochrome P450 (CYP) model substrate metabolites in an in vitro CYP inhibition cocktail.
    Dinger J; Meyer MR; Maurer HH
    Anal Bioanal Chem; 2014 Jul; 406(18):4453-64. PubMed ID: 24830396
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparison of cytochrome P450 inhibition assays for drug discovery using human liver microsomes with LC-MS, rhCYP450 isozymes with fluorescence, and double cocktail with LC-MS.
    Di L; Kerns EH; Li SQ; Carter GT
    Int J Pharm; 2007 Apr; 335(1-2):1-11. PubMed ID: 17137735
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An automated, high-throughput, 384 well Cytochrome P450 cocktail IC50 assay using a rapid resolution LC-MS/MS end-point.
    Youdim KA; Lyons R; Payne L; Jones BC; Saunders K
    J Pharm Biomed Anal; 2008 Sep; 48(1):92-9. PubMed ID: 18584988
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes.
    Wei J; Zhang H; Zhao Q
    Pharm Biol; 2018 Dec; 56(1):363-367. PubMed ID: 30122094
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A high-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography-tandem mass spectrometry.
    Qin CZ; Ren X; Tan ZR; Chen Y; Yin JY; Yu J; Qu J; Zhou HH; Liu ZQ
    Biomed Chromatogr; 2014 Feb; 28(2):197-203. PubMed ID: 23946123
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibitory Effects of Trapping Agents of Sulfur Drug Reactive Intermediates against Major Human Cytochrome P450 Isoforms.
    Sodhi JK; Delarosa EM; Halladay JS; Driscoll JP; Mulder T; Dansette PM; Khojasteh SC
    Int J Mol Sci; 2017 Jul; 18(7):. PubMed ID: 28726718
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of an in vitro drug-drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds.
    Zientek M; Miller H; Smith D; Dunklee MB; Heinle L; Thurston A; Lee C; Hyland R; Fahmi O; Burdette D
    J Pharmacol Toxicol Methods; 2008; 58(3):206-14. PubMed ID: 18634893
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.