286 related articles for article (PubMed ID: 24175747)
1. Small-molecule inhibitors of human LDH5.
Granchi C; Paterni I; Rani R; Minutolo F
Future Med Chem; 2013 Oct; 5(16):1967-91. PubMed ID: 24175747
[TBL] [Abstract][Full Text] [Related]
2. Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy.
Rani R; Kumar V
J Med Chem; 2016 Jan; 59(2):487-96. PubMed ID: 26340601
[TBL] [Abstract][Full Text] [Related]
3. Targeting cancer metabolism to develop human lactate dehydrogenase (hLDH)5 inhibitors.
Zhang SL; He Y; Tam KY
Drug Discov Today; 2018 Jul; 23(7):1407-1415. PubMed ID: 29750903
[TBL] [Abstract][Full Text] [Related]
4. Three-Dimensional Analysis of the Interactions between hLDH5 and Its Inhibitors.
Poli G; Granchi C; Aissaoui M; Minutolo F; Tuccinardi T
Molecules; 2017 Dec; 22(12):. PubMed ID: 29236080
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5.
Granchi C; Roy S; Mottinelli M; Nardini E; Campinoti F; Tuccinardi T; Lanza M; Betti L; Giannaccini G; Lucacchini A; Martinelli A; Macchia M; Minutolo F
Bioorg Med Chem Lett; 2011 Dec; 21(24):7331-6. PubMed ID: 22056743
[TBL] [Abstract][Full Text] [Related]
6. A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by Using a Pharmacophore-based Approach.
Tuccinardi T; Poli G; Corchia I; Granchi C; Lapillo M; Macchia M; Minutolo F; Ortore G; Martinelli A
Mol Inform; 2016 Sep; 35(8-9):434-9. PubMed ID: 27546047
[TBL] [Abstract][Full Text] [Related]
7. N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation.
Granchi C; Roy S; De Simone A; Salvetti I; Tuccinardi T; Martinelli A; Macchia M; Lanza M; Betti L; Giannaccini G; Lucacchini A; Giovannetti E; Sciarrillo R; Peters GJ; Minutolo F
Eur J Med Chem; 2011 Nov; 46(11):5398-407. PubMed ID: 21944286
[TBL] [Abstract][Full Text] [Related]
8. When will small molecule lactate dehydrogenase inhibitors realize their potential in the cancer clinic?
Rani R; Kumar V
Future Med Chem; 2017 Jul; 9(11):1113-1115. PubMed ID: 28722474
[No Abstract] [Full Text] [Related]
9. Lactate Dehydrogenase Inhibition: Biochemical Relevance and Therapeutical Potential.
Laganá G; Barreca D; Calderaro A; Bellocco E
Curr Med Chem; 2019; 26(18):3242-3252. PubMed ID: 28183261
[TBL] [Abstract][Full Text] [Related]
10. Selective active site inhibitors of human lactate dehydrogenases A4, B4, and C4.
Yu Y; Deck JA; Hunsaker LA; Deck LM; Royer RE; Goldberg E; Vander Jagt DL
Biochem Pharmacol; 2001 Jul; 62(1):81-9. PubMed ID: 11377399
[TBL] [Abstract][Full Text] [Related]
11. Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5.
Moorhouse AD; Spiteri C; Sharma P; Zloh M; Moses JE
Chem Commun (Camb); 2011 Jan; 47(1):230-2. PubMed ID: 20676418
[TBL] [Abstract][Full Text] [Related]
12. Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials.
Granchi C; Bertini S; Macchia M; Minutolo F
Curr Med Chem; 2010; 17(7):672-97. PubMed ID: 20088761
[TBL] [Abstract][Full Text] [Related]
13. Computer-aided discovery and biological characterization of human lactate dehydrogenase 5 inhibitors with anti-osteosarcoma activity.
Cao W; Fang L; Teng S; Chen H; Wang Z
Bioorg Med Chem Lett; 2018 Jul; 28(13):2229-2233. PubMed ID: 29861142
[TBL] [Abstract][Full Text] [Related]
14. Human lactate dehydrogenase a inhibitors: a molecular dynamics investigation.
Shi Y; Pinto BM
PLoS One; 2014; 9(1):e86365. PubMed ID: 24466056
[TBL] [Abstract][Full Text] [Related]
15. Development and validation of a docking-based virtual screening platform for the identification of new lactate dehydrogenase inhibitors.
Granchi C; Capecchi A; Del Frate G; Martinelli A; Macchia M; Minutolo F; Tuccinardi T
Molecules; 2015 May; 20(5):8772-90. PubMed ID: 25988609
[TBL] [Abstract][Full Text] [Related]
16. Oxamic acid analogues as LDH-C4-specific competitive inhibitors.
Rodríguez-Páez L; Chena-Taboada MA; Cabrera-Hernández A; Cordero-Martínez J; Wong C
J Enzyme Inhib Med Chem; 2011 Aug; 26(4):579-86. PubMed ID: 21438710
[TBL] [Abstract][Full Text] [Related]
17. Discovery of human lactate dehydrogenase 5 inhibitors (hLDH5) with anti-lung cancer activity through an in silico method and biological validation.
He S; Wang Q
Bioorg Med Chem Lett; 2019 Sep; 29(17):2459-2463. PubMed ID: 31345633
[TBL] [Abstract][Full Text] [Related]
18. Characterization of the Saffron Derivative Crocetin as an Inhibitor of Human Lactate Dehydrogenase 5 in the Antiglycolytic Approach against Cancer.
Granchi C; Fortunato S; Meini S; Rizzolio F; Caligiuri I; Tuccinardi T; Lee HY; Hergenrother PJ; Minutolo F
J Agric Food Chem; 2017 Jul; 65(28):5639-5649. PubMed ID: 28643510
[TBL] [Abstract][Full Text] [Related]
19. Generation of oxamic acid libraries: antimalarials and inhibitors of Plasmodium falciparum lactate dehydrogenase.
Choi SR; Beeler AB; Pradhan A; Watkins EB; Rimoldi JM; Tekwani B; Avery MA
J Comb Chem; 2007; 9(2):292-300. PubMed ID: 17316052
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of lactate dehydrogenase activity as an approach to cancer therapy.
Fiume L; Manerba M; Vettraino M; Di Stefano G
Future Med Chem; 2014 Mar; 6(4):429-45. PubMed ID: 24635523
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]