BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 24175906)

  • 1. Inhibition of transglutaminase 2, a novel target for pulmonary fibrosis, by two small electrophilic molecules.
    Olsen KC; Epa AP; Kulkarni AA; Kottmann RM; McCarthy CE; Johnson GV; Thatcher TH; Phipps RP; Sime PJ
    Am J Respir Cell Mol Biol; 2014 Apr; 50(4):737-47. PubMed ID: 24175906
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism.
    Ferguson HE; Thatcher TH; Olsen KC; Garcia-Bates TM; Baglole CJ; Kottmann RM; Strong ER; Phipps RP; Sime PJ
    Am J Physiol Lung Cell Mol Physiol; 2009 Nov; 297(5):L912-9. PubMed ID: 19734319
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.
    Ferguson HE; Kulkarni A; Lehmann GM; Garcia-Bates TM; Thatcher TH; Huxlin KR; Phipps RP; Sime PJ
    Am J Respir Cell Mol Biol; 2009 Dec; 41(6):722-30. PubMed ID: 19286977
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal transduction pathway in HT-29 colon cancer cells.
    Chen ZY; Tseng CC
    Mol Pharmacol; 2005 Nov; 68(5):1203-13. PubMed ID: 16077033
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling.
    Mix KS; Coon CI; Rosen ED; Suh N; Sporn MB; Brinckerhoff CE
    Mol Pharmacol; 2004 Feb; 65(2):309-18. PubMed ID: 14742672
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transglutaminase 2: a novel therapeutic target for idiopathic pulmonary fibrosis using selective small molecule inhibitors.
    Fell S; Wang Z; Blanchard A; Nanthakumar C; Griffin M
    Amino Acids; 2021 Feb; 53(2):205-217. PubMed ID: 33474654
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring.
    Kuriyan AE; Lehmann GM; Kulkarni AA; Woeller CF; Feldon SE; Hindman HB; Sime PJ; Huxlin KR; Phipps RP
    Exp Eye Res; 2012 Jan; 94(1):136-45. PubMed ID: 22178289
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transglutaminase 2 and its role in pulmonary fibrosis.
    Olsen KC; Sapinoro RE; Kottmann RM; Kulkarni AA; Iismaa SE; Johnson GV; Thatcher TH; Phipps RP; Sime PJ
    Am J Respir Crit Care Med; 2011 Sep; 184(6):699-707. PubMed ID: 21700912
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Extracellular Matrix Cross-Linking Enhances Fibroblast Growth and Protects against Matrix Proteolysis in Lung Fibrosis.
    Philp CJ; Siebeke I; Clements D; Miller S; Habgood A; John AE; Navaratnam V; Hubbard RB; Jenkins G; Johnson SR
    Am J Respir Cell Mol Biol; 2018 May; 58(5):594-603. PubMed ID: 29053339
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 15-Deoxy-Δ
    Yamamoto Y; Koma H; Yagami T
    Biol Pharm Bull; 2020; 43(1):153-157. PubMed ID: 31902920
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 15-Deoxy-Delta12,14-prostaglandin J2 inhibits IL-1beta-induced cyclooxygenase-2 expression in mesangial cells.
    Sawano H; Haneda M; Sugimoto T; Inoki K; Koya D; Kikkawa R
    Kidney Int; 2002 Jun; 61(6):1957-67. PubMed ID: 12028436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 15-Deoxy-Δ-12, 14-prostaglandin J2 acts cooperatively with prednisolone to reduce TGF-β-induced pro-fibrotic pathways in human osteoarthritis fibroblasts.
    Vaamonde-Garcia C; Malaise O; Charlier E; Deroyer C; Neuville S; Gillet P; Kurth W; Meijide-Failde R; Malaise MG; de Seny D
    Biochem Pharmacol; 2019 Jul; 165():66-78. PubMed ID: 30936016
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 15-deoxy-Δ(12,14) -prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts.
    Lin TH; Tang CH; Wu K; Fong YC; Yang RS; Fu WM
    J Cell Physiol; 2011 Dec; 226(12):3242-50. PubMed ID: 21344384
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis.
    Hostettler KE; Zhong J; Papakonstantinou E; Karakiulakis G; Tamm M; Seidel P; Sun Q; Mandal J; Lardinois D; Lambers C; Roth M
    Respir Res; 2014 Dec; 15(1):157. PubMed ID: 25496490
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma.
    Giri S; Rattan R; Singh AK; Singh I
    J Immunol; 2004 Oct; 173(8):5196-208. PubMed ID: 15470065
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A natural PPAR-gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions.
    Kimura H; Li X; Torii K; Okada T; Takahashi N; Fujii H; Ishihara S; Yoshida H
    Nephrol Dial Transplant; 2008 Aug; 23(8):2496-503. PubMed ID: 18367541
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of IL-10-induced STAT3 activation by 15-deoxy-Delta12,14-prostaglandin J2.
    Ji JD; Kim HJ; Rho YH; Choi SJ; Lee YH; Cheon HJ; Sohn J; Song GG
    Rheumatology (Oxford); 2005 Aug; 44(8):983-8. PubMed ID: 15840591
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis.
    Burgess HA; Daugherty LE; Thatcher TH; Lakatos HF; Ray DM; Redonnet M; Phipps RP; Sime PJ
    Am J Physiol Lung Cell Mol Physiol; 2005 Jun; 288(6):L1146-53. PubMed ID: 15734787
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis.
    Kulkarni AA; Thatcher TH; Olsen KC; Maggirwar SB; Phipps RP; Sime PJ
    PLoS One; 2011 Jan; 6(1):e15909. PubMed ID: 21253589
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma.
    Wilmer WA; Dixon C; Lu L; Hilbelink T; Rovin BH
    Biochem Biophys Res Commun; 2001 Feb; 281(1):57-62. PubMed ID: 11178960
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.