123 related articles for article (PubMed ID: 24176395)
1. 2-(2-Phenylmorpholin-4-yl)pyrimidin-4(3H)-ones; a new class of potent, selective and orally active glycogen synthase kinase-3β inhibitors.
Fukunaga K; Uehara F; Aritomo K; Shoda A; Hiki S; Okuyama M; Usui Y; Watanabe K; Yamakoshi K; Kohara T; Hanano T; Tanaka H; Tsuchiya S; Sunada S; Saito K; Eguchi J; Yuki S; Asano S; Tanaka S; Mori A; Yamagami K; Baba H; Horikawa T; Fujimura M
Bioorg Med Chem Lett; 2013 Dec; 23(24):6933-7. PubMed ID: 24176395
[TBL] [Abstract][Full Text] [Related]
2. 6-(4-Pyridyl)pyrimidin-4(3H)-ones as CNS penetrant glycogen synthase kinase-3β inhibitors.
Uehara F; Shoda A; Aritomo K; Fukunaga K; Watanabe K; Ando R; Shinoda M; Ueno H; Kubodera H; Sunada S; Saito K; Kaji T; Asano S; Eguchi J; Yuki S; Tanaka S; Yoneyama Y; Niwa T
Bioorg Med Chem Lett; 2013 Dec; 23(24):6928-32. PubMed ID: 24094818
[TBL] [Abstract][Full Text] [Related]
3. Discovery of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally-active GSK-3β inhibitors for Alzheimer's disease.
Fukunaga K; Sakai D; Watanabe K; Nakayama K; Kohara T; Tanaka H; Sunada S; Nabeno M; Okamoto M; Saito K; Eguchi J; Mori A; Tanaka S; Inazawa K; Horikawa T
Bioorg Med Chem Lett; 2015 Mar; 25(5):1086-91. PubMed ID: 25655721
[TBL] [Abstract][Full Text] [Related]
4. Discovery of novel 2-(4-aryl-2-methylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors.
Kohara T; Nakayama K; Watanabe K; Kusaka SI; Sakai D; Tanaka H; Fukunaga K; Sunada S; Nabeno M; Saito KI; Eguchi JI; Mori A; Tanaka S; Bessho T; Takiguchi-Hayashi K; Horikawa T
Bioorg Med Chem Lett; 2017 Aug; 27(16):3733-3738. PubMed ID: 28712706
[TBL] [Abstract][Full Text] [Related]
5. Discovery of novel 2-(3-phenylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors.
Usui Y; Uehara F; Hiki S; Watanabe K; Tanaka H; Shouda A; Yokoshima S; Aritomo K; Adachi T; Fukunaga K; Sunada S; Nabeno M; Saito KI; Eguchi JI; Yamagami K; Asano S; Tanaka S; Yuki S; Yoshii N; Fujimura M; Horikawa T
Bioorg Med Chem Lett; 2017 Aug; 27(16):3726-3732. PubMed ID: 28712708
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of 3-benzisoxazolyl-4-indolylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3β.
Ye Q; Li M; Zhou Y; Pang T; Xu L; Cao J; Han L; Li Y; Wang W; Gao J; Li J
Molecules; 2013 May; 18(5):5498-516. PubMed ID: 23669633
[TBL] [Abstract][Full Text] [Related]
7. Helicobacter pylori filtrate induces Alzheimer-like tau hyperphosphorylation by activating glycogen synthase kinase-3β.
Wang XL; Zeng J; Yang Y; Xiong Y; Zhang ZH; Qiu M; Yan X; Sun XY; Tuo QZ; Liu R; Wang JZ
J Alzheimers Dis; 2015; 43(1):153-65. PubMed ID: 25079798
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of glycogen synthase kinase-3β by Angelica sinensis extract decreases β-amyloid-induced neurotoxicity and tau phosphorylation in cultured cortical neurons.
Zhang Z; Zhao R; Qi J; Wen S; Tang Y; Wang D
J Neurosci Res; 2011 Mar; 89(3):437-47. PubMed ID: 21259330
[TBL] [Abstract][Full Text] [Related]
9. Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3β inhibitors through virtual screening.
Zhang P; Hu HR; Huang ZH; Lei JY; Chu Y; Ye DY
Bioorg Med Chem Lett; 2012 Dec; 22(23):7232-6. PubMed ID: 23099099
[TBL] [Abstract][Full Text] [Related]
10. Bip enhanced the association of GSK-3β with tau during ER stress both in vivo and in vitro.
Liu ZC; Fu ZQ; Song J; Zhang JY; Wei YP; Chu J; Han L; Qu N; Wang JZ; Tian Q
J Alzheimers Dis; 2012; 29(4):727-40. PubMed ID: 22460328
[TBL] [Abstract][Full Text] [Related]
11. 2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta with good brain permeability.
Saitoh M; Kunitomo J; Kimura E; Iwashita H; Uno Y; Onishi T; Uchiyama N; Kawamoto T; Tanaka T; Mol CD; Dougan DR; Textor GP; Snell GP; Takizawa M; Itoh F; Kori M
J Med Chem; 2009 Oct; 52(20):6270-86. PubMed ID: 19775160
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of Novel Pyrimidin-4-One Bearing Piperazine Ring-Based Amides as Glycogen Synthase Kinase-3β Inhibitors with Antidepressant Activity.
Khan I; Tantray MA; Hamid H; Alam MS; Kalam A; Shaikh F; Shah A; Hussain F
Chem Biol Drug Des; 2016 May; 87(5):764-72. PubMed ID: 26714831
[TBL] [Abstract][Full Text] [Related]
13. LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3β in vivo and in vitro.
Fu ZQ; Yang Y; Song J; Jiang Q; Lin ZC; Wang Q; Zhu LQ; Wang JZ; Tian Q
J Alzheimers Dis; 2010; 21(4):1107-17. PubMed ID: 21504119
[TBL] [Abstract][Full Text] [Related]
14. Nitric oxide induces tau hyperphosphorylation via glycogen synthase kinase-3beta activation.
Zhang YJ; Xu YF; Liu YH; Yin J; Wang JZ
FEBS Lett; 2005 Nov; 579(27):6230-6. PubMed ID: 16253246
[TBL] [Abstract][Full Text] [Related]
15. The marine natural-derived inhibitors of glycogen synthase kinase-3beta phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modeling.
Khanfar MA; Asal BA; Mudit M; Kaddoumi A; El Sayed KA
Bioorg Med Chem; 2009 Aug; 17(16):6032-9. PubMed ID: 19616957
[TBL] [Abstract][Full Text] [Related]
16. Amyloid-beta-induced neurotoxicity is reduced by inhibition of glycogen synthase kinase-3.
Koh SH; Noh MY; Kim SH
Brain Res; 2008 Jan; 1188():254-62. PubMed ID: 18031715
[TBL] [Abstract][Full Text] [Related]
17. Discovery of potent and bioavailable GSK-3beta inhibitors.
Gong L; Hirschfeld D; Tan YC; Heather Hogg J; Peltz G; Avnur Z; Dunten P
Bioorg Med Chem Lett; 2010 Mar; 20(5):1693-6. PubMed ID: 20138512
[TBL] [Abstract][Full Text] [Related]
18. Role of GSK-3beta activation and alpha7 nAChRs in Abeta(1-42)-induced tau phosphorylation in PC12 cells.
Hu M; Waring JF; Gopalakrishnan M; Li J
J Neurochem; 2008 Aug; 106(3):1371-7. PubMed ID: 18485099
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, and evaluation of 3-aryl-4-pyrrolyl-maleimides as glycogen synthase kinase-3β inhibitors.
Ye Q; Li M; Zhou YB; Cao JY; Xu L; Li YJ; Han L; Gao JR; Hu YZ; Li J
Arch Pharm (Weinheim); 2013 May; 346(5):349-58. PubMed ID: 23585245
[TBL] [Abstract][Full Text] [Related]
20. Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3beta in SH-SY5Y neuroblastoma cells.
An WL; Bjorkdahl C; Liu R; Cowburn RF; Winblad B; Pei JJ
J Neurochem; 2005 Mar; 92(5):1104-15. PubMed ID: 15715661
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
