BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 24182517)

  • 21. Metabolism and DNA single strand breaks induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its analogues in primary culture of rat hepatocytes.
    Liu LL; Alaoui-Jamali MA; el Alami N; Castonguay A
    Cancer Res; 1990 Mar; 50(6):1810-6. PubMed ID: 2306734
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Comparative levels of O6-methylguanine, pyridyloxobutyl-, and pyridylhydroxybutyl-DNA adducts in lung and liver of rats treated chronically with the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Upadhyaya P; Lindgren BR; Hecht SS
    Drug Metab Dispos; 2009 Jun; 37(6):1147-51. PubMed ID: 19324941
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Dihydromethysticin from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice.
    Narayanapillai SC; Balbo S; Leitzman P; Grill AE; Upadhyaya P; Shaik AA; Zhou B; O'Sullivan MG; Peterson LA; Lu J; Hecht SS; Xing C
    Carcinogenesis; 2014 Oct; 35(10):2365-72. PubMed ID: 25053626
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Role of CYP2A5 in the bioactivation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.
    Zhou X; D'Agostino J; Xie F; Ding X
    J Pharmacol Exp Ther; 2012 Apr; 341(1):233-41. PubMed ID: 22262919
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
    Smith TJ; Guo Z; Gonzalez FJ; Guengerich FP; Stoner GD; Yang CS
    Cancer Res; 1992 Apr; 52(7):1757-63. PubMed ID: 1312898
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
    Richter E; Engl J; Friesenegger S; Tricker AR
    Chem Res Toxicol; 2009 Jun; 22(6):1008-17. PubMed ID: 19408892
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Evidence for an important role of DNA pyridyloxobutylation in rat lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: effects of dose and phenethyl isothiocyanate.
    Staretz ME; Foiles PG; Miglietta LM; Hecht SS
    Cancer Res; 1997 Jan; 57(2):259-66. PubMed ID: 9000565
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Role of DNA methylation in the activation of proto-oncogenes and the induction of pulmonary neoplasia by nitrosamines.
    Belinsky SA; Devereux TR; Anderson MW
    Mutat Res; 1990; 233(1-2):105-16. PubMed ID: 2233792
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mgmt deficiency alters the in vivo mutational spectrum of tissues exposed to the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Sandercock LE; Hahn JN; Li L; Luchman HA; Giesbrecht JL; Peterson LA; Jirik FR
    Carcinogenesis; 2008 Apr; 29(4):866-74. PubMed ID: 18281247
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Formation and accumulation of pyridyloxobutyl DNA adducts in F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Lao Y; Yu N; Kassie F; Villalta PW; Hecht SS
    Chem Res Toxicol; 2007 Feb; 20(2):235-45. PubMed ID: 17305407
    [TBL] [Abstract][Full Text] [Related]  

  • 31. K-ras gene sequence effects on the formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-DNA adducts.
    Ziegel R; Shallop A; Jones R; Tretyakova N
    Chem Res Toxicol; 2003 Apr; 16(4):541-50. PubMed ID: 12703972
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Endogenous 5-methylcytosine protects neighboring guanines from N7 and O6-methylation and O6-pyridyloxobutylation by the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Ziegel R; Shallop A; Upadhyaya P; Jones R; Tretyakova N
    Biochemistry; 2004 Jan; 43(2):540-9. PubMed ID: 14717610
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Stereospecific deuterium substitution attenuates the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Jalas JR; McIntee EJ; Kenney PM; Upadhyaya P; Peterson LA; Hecht SS
    Chem Res Toxicol; 2003 Jun; 16(6):794-806. PubMed ID: 12807363
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Array CGH analysis reveals chromosomal aberrations in mouse lung adenocarcinomas induced by the human lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Herzog CR; Desai D; Amin S
    Biochem Biophys Res Commun; 2006 Mar; 341(3):856-63. PubMed ID: 16455056
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.
    Carmella SG; Borukhova A; Akerkar SA; Hecht SS
    Cancer Epidemiol Biomarkers Prev; 1997 Feb; 6(2):113-20. PubMed ID: 9037562
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Belinsky SA; Foley JF; White CM; Anderson MW; Maronpot RR
    Cancer Res; 1990 Jun; 50(12):3772-80. PubMed ID: 2340522
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Formation and repair of pyridyloxobutyl DNA adducts and their relationship to tumor yield in A/J mice.
    Urban AM; Upadhyaya P; Cao Q; Peterson LA
    Chem Res Toxicol; 2012 Oct; 25(10):2167-78. PubMed ID: 22928598
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Kinetics of DNA methylation by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 rats.
    Castonguay A; Tharp R; Hecht SS
    IARC Sci Publ; 1984; (57):805-10. PubMed ID: 6543440
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Placental transfer of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone instilled intratracheally in Syrian golden hamsters.
    Jorquera R; Castonguay A; Schuller HM
    Cancer Res; 1992 Jun; 52(12):3273-80. PubMed ID: 1596885
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Stable isotope labeling-mass spectrometry analysis of methyl- and pyridyloxobutyl-guanine adducts of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in p53-derived DNA sequences.
    Rajesh M; Wang G; Jones R; Tretyakova N
    Biochemistry; 2005 Feb; 44(6):2197-207. PubMed ID: 15697245
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.