238 related articles for article (PubMed ID: 24184776)
1. Synthesis, biological evaluation and molecular docking studies of flavone and isoflavone derivatives as a novel class of KSP (kinesin spindle protein) inhibitors.
Dong JJ; Li QS; Liu ZP; Wang SF; Zhao MY; Yang YH; Wang XM; Zhu HL
Eur J Med Chem; 2013; 70():427-33. PubMed ID: 24184776
[TBL] [Abstract][Full Text] [Related]
2. Discovery of tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin KSP.
Liu F; Yu LQ; Jiang C; Yang L; Wu WT; You QD
Bioorg Med Chem; 2010 Jun; 18(12):4167-77. PubMed ID: 20537544
[TBL] [Abstract][Full Text] [Related]
3. De novo design, synthesis and biological evaluation of 1,4-dihydroquinolin-4-ones and 1,2,3,4-tetrahydroquinazolin-4-ones as potent kinesin spindle protein (KSP) inhibitors.
Jiang C; Yang L; Wu WT; Guo QL; You QD
Bioorg Med Chem; 2011 Sep; 19(18):5612-27. PubMed ID: 21856161
[TBL] [Abstract][Full Text] [Related]
4. [Synthesis and antitumor activity of novel tetrahydro-beta-carboline derivatives as KSP inhibitors].
Ruan XQ; Chen M; Wu WT; You QD
Yao Xue Xue Bao; 2013 Jul; 48(7):1119-23. PubMed ID: 24133978
[TBL] [Abstract][Full Text] [Related]
5. Ligand- and structure-based in silico studies to identify kinesin spindle protein (KSP) inhibitors as potential anticancer agents.
Balakumar C; Ramesh M; Tham CL; Khathi SP; Kozielski F; Srinivasulu C; Hampannavar GA; Sayyad N; Soliman ME; Karpoormath R
J Biomol Struct Dyn; 2018 Nov; 36(14):3687-3704. PubMed ID: 29064326
[TBL] [Abstract][Full Text] [Related]
6. Receptor-ligand interaction-based virtual screening for novel Eg5/kinesin spindle protein inhibitors.
Nagarajan S; Skoufias DA; Kozielski F; Pae AN
J Med Chem; 2012 Mar; 55(6):2561-73. PubMed ID: 22309208
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and evaluation of biphenyl compounds as kinesin spindle protein inhibitors.
Holland JP; Kang A; Cohrs S; Selivanova SV; Milicevic Sephton S; Betzel T; Frey D; Wieser M; Jaussi R; Kammerer RA; Schibli R; Fischer E
Chem Biodivers; 2013 Apr; 10(4):538-55. PubMed ID: 23576341
[TBL] [Abstract][Full Text] [Related]
8. Synthesis of N-(1-(6-acetamido-5-phenylpyrimidin-4-yl) piperidin-3-yl) amide derivatives as potential inhibitors for mitotic kinesin spindle protein.
Muthuraja P; Himesh M; Prakash S; Venkatasubramanian U; Manisankar P
Eur J Med Chem; 2018 Mar; 148():106-115. PubMed ID: 29454915
[TBL] [Abstract][Full Text] [Related]
9. Structure-based design of new KSP-Eg5 inhibitors assisted by a targeted multicomponent reaction.
Carbajales C; Prado MÁ; Gutiérrez-de-Terán H; Cores A; Azuaje J; Novio S; Nuñez MJ; Fernández-García B; Sotelo E; García-Mera X; Sánchez-Lazo P; Freire-Garabal M; Coelho A
Chembiochem; 2014 Jul; 15(10):1471-80. PubMed ID: 24943831
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and molecular docking study of new monastrol analogues as kinesin spindle protein inhibitors.
El-Hamamsy MH; Sharafeldin NA; El-Moselhy TF; Tawfik HO
Arch Pharm (Weinheim); 2020 Aug; 353(8):e2000060. PubMed ID: 32452567
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, and cytotoxic and antiplatelet activities of oxime- and methyloxime-containing flavone, isoflavone, and xanthone derivatives.
Wang TC; Chen IL; Lu CM; Kuo DH; Liao CH
Chem Biodivers; 2005 Feb; 2(2):253-63. PubMed ID: 17191978
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, biological evaluation, and molecular docking studies of N-((1,3-diphenyl-1H-pyrazol-4-yl)methyl)aniline derivatives as novel anticancer agents.
Huang XF; Lu X; Zhang Y; Song GQ; He QL; Li QS; Yang XH; Wei Y; Zhu HL
Bioorg Med Chem; 2012 Aug; 20(16):4895-900. PubMed ID: 22819191
[TBL] [Abstract][Full Text] [Related]
13. Novel ATP-competitive kinesin spindle protein inhibitors.
Parrish CA; Adams ND; Auger KR; Burgess JL; Carson JD; Chaudhari AM; Copeland RA; Diamond MA; Donatelli CA; Duffy KJ; Faucette LF; Finer JT; Huffman WF; Hugger ED; Jackson JR; Knight SD; Luo L; Moore ML; Newlander KA; Ridgers LH; Sakowicz R; Shaw AN; Sung CM; Sutton D; Wood KW; Zhang SY; Zimmerman MN; Dhanak D
J Med Chem; 2007 Oct; 50(20):4939-52. PubMed ID: 17725339
[TBL] [Abstract][Full Text] [Related]
14. Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP.
Roecker AJ; Coleman PJ; Mercer SP; Schreier JD; Buser CA; Walsh ES; Hamilton K; Lobell RB; Tao W; Diehl RE; South VJ; Davide JP; Kohl NE; Yan Y; Kuo LC; Li C; Fernandez-Metzler C; Mahan EA; Prueksaritanont T; Hartman GD
Bioorg Med Chem Lett; 2007 Oct; 17(20):5677-82. PubMed ID: 17766111
[TBL] [Abstract][Full Text] [Related]
15. [Synthesis and biological evaluation of tetrahydro-beta-carline derivatives].
Ruan XQ; You QD; Yang L; Wu WT
Yao Xue Xue Bao; 2008 Aug; 43(8):828-32. PubMed ID: 18956775
[TBL] [Abstract][Full Text] [Related]
16. Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds.
Oishi S; Watanabe T; Sawada J; Asai A; Ohno H; Fujii N
J Med Chem; 2010 Jul; 53(13):5054-8. PubMed ID: 20521839
[TBL] [Abstract][Full Text] [Related]
17. KSP inhibitors as antimitotic agents.
Pérez-Melero C
Curr Top Med Chem; 2014; 14(20):2286-311. PubMed ID: 25434354
[TBL] [Abstract][Full Text] [Related]
18. Discovery of novel spiro 1,3,4-thiadiazolines as potent, orally bioavailable and brain penetrant KSP inhibitors.
Mansoor UF; Angeles AR; Dai C; Yang L; Vitharana D; Basso AD; Gray K; Tang H; Liu M; Liang L; Allbritton O; Siddiqui MA
Bioorg Med Chem; 2015 May; 23(10):2424-34. PubMed ID: 25868746
[TBL] [Abstract][Full Text] [Related]
19. Structure-activity relationships of carboline and carbazole derivatives as a novel class of ATP-competitive kinesin spindle protein inhibitors.
Takeuchi T; Oishi S; Watanabe T; Ohno H; Sawada J; Matsuno K; Asai A; Asada N; Kitaura K; Fujii N
J Med Chem; 2011 Jul; 54(13):4839-46. PubMed ID: 21599002
[TBL] [Abstract][Full Text] [Related]
20. Synthesis, α-glucosidase inhibitory and molecular docking studies of prenylated and geranylated flavones, isoflavones and chalcones.
Sun H; Li Y; Zhang X; Lei Y; Ding W; Zhao X; Wang H; Song X; Yao Q; Zhang Y; Ma Y; Wang R; Zhu T; Yu P
Bioorg Med Chem Lett; 2015 Oct; 25(20):4567-71. PubMed ID: 26351039
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
