These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 24184776)

  • 1. Synthesis, biological evaluation and molecular docking studies of flavone and isoflavone derivatives as a novel class of KSP (kinesin spindle protein) inhibitors.
    Dong JJ; Li QS; Liu ZP; Wang SF; Zhao MY; Yang YH; Wang XM; Zhu HL
    Eur J Med Chem; 2013; 70():427-33. PubMed ID: 24184776
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin KSP.
    Liu F; Yu LQ; Jiang C; Yang L; Wu WT; You QD
    Bioorg Med Chem; 2010 Jun; 18(12):4167-77. PubMed ID: 20537544
    [TBL] [Abstract][Full Text] [Related]  

  • 3. De novo design, synthesis and biological evaluation of 1,4-dihydroquinolin-4-ones and 1,2,3,4-tetrahydroquinazolin-4-ones as potent kinesin spindle protein (KSP) inhibitors.
    Jiang C; Yang L; Wu WT; Guo QL; You QD
    Bioorg Med Chem; 2011 Sep; 19(18):5612-27. PubMed ID: 21856161
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Synthesis and antitumor activity of novel tetrahydro-beta-carboline derivatives as KSP inhibitors].
    Ruan XQ; Chen M; Wu WT; You QD
    Yao Xue Xue Bao; 2013 Jul; 48(7):1119-23. PubMed ID: 24133978
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ligand- and structure-based in silico studies to identify kinesin spindle protein (KSP) inhibitors as potential anticancer agents.
    Balakumar C; Ramesh M; Tham CL; Khathi SP; Kozielski F; Srinivasulu C; Hampannavar GA; Sayyad N; Soliman ME; Karpoormath R
    J Biomol Struct Dyn; 2018 Nov; 36(14):3687-3704. PubMed ID: 29064326
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Receptor-ligand interaction-based virtual screening for novel Eg5/kinesin spindle protein inhibitors.
    Nagarajan S; Skoufias DA; Kozielski F; Pae AN
    J Med Chem; 2012 Mar; 55(6):2561-73. PubMed ID: 22309208
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and evaluation of biphenyl compounds as kinesin spindle protein inhibitors.
    Holland JP; Kang A; Cohrs S; Selivanova SV; Milicevic Sephton S; Betzel T; Frey D; Wieser M; Jaussi R; Kammerer RA; Schibli R; Fischer E
    Chem Biodivers; 2013 Apr; 10(4):538-55. PubMed ID: 23576341
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of N-(1-(6-acetamido-5-phenylpyrimidin-4-yl) piperidin-3-yl) amide derivatives as potential inhibitors for mitotic kinesin spindle protein.
    Muthuraja P; Himesh M; Prakash S; Venkatasubramanian U; Manisankar P
    Eur J Med Chem; 2018 Mar; 148():106-115. PubMed ID: 29454915
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-based design of new KSP-Eg5 inhibitors assisted by a targeted multicomponent reaction.
    Carbajales C; Prado MÁ; Gutiérrez-de-Terán H; Cores A; Azuaje J; Novio S; Nuñez MJ; Fernández-García B; Sotelo E; García-Mera X; Sánchez-Lazo P; Freire-Garabal M; Coelho A
    Chembiochem; 2014 Jul; 15(10):1471-80. PubMed ID: 24943831
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, and molecular docking study of new monastrol analogues as kinesin spindle protein inhibitors.
    El-Hamamsy MH; Sharafeldin NA; El-Moselhy TF; Tawfik HO
    Arch Pharm (Weinheim); 2020 Aug; 353(8):e2000060. PubMed ID: 32452567
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, and cytotoxic and antiplatelet activities of oxime- and methyloxime-containing flavone, isoflavone, and xanthone derivatives.
    Wang TC; Chen IL; Lu CM; Kuo DH; Liao CH
    Chem Biodivers; 2005 Feb; 2(2):253-63. PubMed ID: 17191978
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, biological evaluation, and molecular docking studies of N-((1,3-diphenyl-1H-pyrazol-4-yl)methyl)aniline derivatives as novel anticancer agents.
    Huang XF; Lu X; Zhang Y; Song GQ; He QL; Li QS; Yang XH; Wei Y; Zhu HL
    Bioorg Med Chem; 2012 Aug; 20(16):4895-900. PubMed ID: 22819191
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel ATP-competitive kinesin spindle protein inhibitors.
    Parrish CA; Adams ND; Auger KR; Burgess JL; Carson JD; Chaudhari AM; Copeland RA; Diamond MA; Donatelli CA; Duffy KJ; Faucette LF; Finer JT; Huffman WF; Hugger ED; Jackson JR; Knight SD; Luo L; Moore ML; Newlander KA; Ridgers LH; Sakowicz R; Shaw AN; Sung CM; Sutton D; Wood KW; Zhang SY; Zimmerman MN; Dhanak D
    J Med Chem; 2007 Oct; 50(20):4939-52. PubMed ID: 17725339
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP.
    Roecker AJ; Coleman PJ; Mercer SP; Schreier JD; Buser CA; Walsh ES; Hamilton K; Lobell RB; Tao W; Diehl RE; South VJ; Davide JP; Kohl NE; Yan Y; Kuo LC; Li C; Fernandez-Metzler C; Mahan EA; Prueksaritanont T; Hartman GD
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5677-82. PubMed ID: 17766111
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Synthesis and biological evaluation of tetrahydro-beta-carline derivatives].
    Ruan XQ; You QD; Yang L; Wu WT
    Yao Xue Xue Bao; 2008 Aug; 43(8):828-32. PubMed ID: 18956775
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds.
    Oishi S; Watanabe T; Sawada J; Asai A; Ohno H; Fujii N
    J Med Chem; 2010 Jul; 53(13):5054-8. PubMed ID: 20521839
    [TBL] [Abstract][Full Text] [Related]  

  • 17. KSP inhibitors as antimitotic agents.
    Pérez-Melero C
    Curr Top Med Chem; 2014; 14(20):2286-311. PubMed ID: 25434354
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of novel spiro 1,3,4-thiadiazolines as potent, orally bioavailable and brain penetrant KSP inhibitors.
    Mansoor UF; Angeles AR; Dai C; Yang L; Vitharana D; Basso AD; Gray K; Tang H; Liu M; Liang L; Allbritton O; Siddiqui MA
    Bioorg Med Chem; 2015 May; 23(10):2424-34. PubMed ID: 25868746
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationships of carboline and carbazole derivatives as a novel class of ATP-competitive kinesin spindle protein inhibitors.
    Takeuchi T; Oishi S; Watanabe T; Ohno H; Sawada J; Matsuno K; Asai A; Asada N; Kitaura K; Fujii N
    J Med Chem; 2011 Jul; 54(13):4839-46. PubMed ID: 21599002
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, α-glucosidase inhibitory and molecular docking studies of prenylated and geranylated flavones, isoflavones and chalcones.
    Sun H; Li Y; Zhang X; Lei Y; Ding W; Zhao X; Wang H; Song X; Yao Q; Zhang Y; Ma Y; Wang R; Zhu T; Yu P
    Bioorg Med Chem Lett; 2015 Oct; 25(20):4567-71. PubMed ID: 26351039
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.