BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

444 related articles for article (PubMed ID: 24185376)

  • 1. Novel water-soluble prodrugs of acyclovir cleavable by the dipeptidyl-peptidase IV (DPP IV/CD26) enzyme.
    Diez-Torrubia A; Cabrera S; de Castro S; García-Aparicio C; Mulder G; De Meester I; Camarasa MJ; Balzarini J; Velázquez S
    Eur J Med Chem; 2013; 70():456-68. PubMed ID: 24185376
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues.
    Diez-Torrubia A; Balzarini J; Andrei G; Snoeck R; De Meester I; Camarasa MJ; Velázquez S
    J Med Chem; 2011 Mar; 54(6):1927-42. PubMed ID: 21332170
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to different amine-containing drugs.
    Diez-Torrubia A; García-Aparicio C; Cabrera S; De Meester I; Balzarini J; Camarasa MJ; Velázquez S
    J Med Chem; 2010 Jan; 53(2):559-72. PubMed ID: 20000418
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dipeptidyl peptidase IV (DPPIV/CD26)-based prodrugs of hydroxy-containing drugs.
    Diez-Torrubia A; Cabrera S; Lambeir AM; Balzarini J; Camarasa MJ; Velázquez S
    ChemMedChem; 2012 Apr; 7(4):618-28. PubMed ID: 22307932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dipeptidyl peptidase IV-activated prodrugs of anti-varicella zoster virus bicyclic nucleoside analogues containing different self-cleavage spacer systems.
    Diez-Torrubia A; Cabrera S; De Meester I; Camarasa MJ; Balzarini J; Velázquez S
    ChemMedChem; 2012 Sep; 7(9):1612-22. PubMed ID: 22887971
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Efficient conversion of tetrapeptide-based TSAO prodrugs to the parent drug by dipeptidyl-peptidase IV (DPPIV/CD26).
    García-Aparicio C; Diez-Torrubia A; Balzarini J; Lambeir AM; Velázquez S; Camarasa MJ
    Antiviral Res; 2007 Nov; 76(2):130-9. PubMed ID: 17675255
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships for dipeptide prodrugs of acyclovir: implications for prodrug design.
    Santos CR; Capela R; Pereira CS; Valente E; Gouveia L; Pannecouque C; De Clercq E; Moreira R; Gomes P
    Eur J Med Chem; 2009 Jun; 44(6):2339-46. PubMed ID: 18848738
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dipeptidyl-peptidase IV (DPP IV/CD26)-activated prodrugs: a successful strategy for improving water solubility and oral bioavailability.
    Velázquez S; de Castro S; Diez-Torrubia A; Balzarini J; Camarasa MJ
    Curr Med Chem; 2015; 22(8):1041-54. PubMed ID: 25620096
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A new homodimer of aciclovir as a prodrug with increased solubility and antiviral activity.
    Brandi G; Rossi L; Schiavano GF; Millo E; Magnani M
    Int J Antimicrob Agents; 2009 Aug; 34(2):177-80. PubMed ID: 19394201
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter.
    Han H; de Vrueh RL; Rhie JK; Covitz KM; Smith PL; Lee CP; Oh DM; Sadée W; Amidon GL
    Pharm Res; 1998 Aug; 15(8):1154-9. PubMed ID: 9706043
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Simultaneous modulation of transport and metabolism of acyclovir prodrugs across rabbit cornea: An approach involving enzyme inhibitors.
    Katragadda S; Talluri RS; Mitra AK
    Int J Pharm; 2006 Aug; 320(1-2):104-13. PubMed ID: 16720085
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and discovery of a novel dipeptidyl-peptidase IV (CD26)-based prodrug approach.
    García-Aparicio C; Bonache MC; De Meester I; San-Félix A; Balzarini J; Camarasa MJ; Velazquez S
    J Med Chem; 2006 Aug; 49(17):5339-51. PubMed ID: 16913724
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dipeptidyl peptidase-4 greatly contributes to the hydrolysis of vildagliptin in human liver.
    Asakura M; Fujii H; Atsuda K; Itoh T; Fujiwara R
    Drug Metab Dispos; 2015 Apr; 43(4):477-84. PubMed ID: 25597851
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tailoring acyclovir prodrugs with enhanced antiviral activity: rational design, synthesis, human plasma stability and in vitro evaluation.
    Chayrov RL; Stylos EK; Chatziathanasiadou MV; Chuchkov KN; Tencheva AI; Kostagianni AD; Milkova TS; Angelova AL; Galabov AS; Shishkov SA; Todorov DG; Tzakos AG; Stankova IG
    Amino Acids; 2018 Aug; 50(8):1131-1143. PubMed ID: 29779181
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel biotinylated lipid prodrugs of acyclovir for the treatment of herpetic keratitis (HK): transporter recognition, tissue stability and antiviral activity.
    Vadlapudi AD; Vadlapatla RK; Earla R; Sirimulla S; Bailey JB; Pal D; Mitra AK
    Pharm Res; 2013 Aug; 30(8):2063-76. PubMed ID: 23657675
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The dipeptidyl peptidase IV (CD26, EC 3.4.14.5) inhibitor vildagliptin is a potent antihyperalgesic in rats by promoting endomorphin-2 generation in the spinal cord.
    Király K; Lambeir AM; Szalai J; Szentirmay A; Luyten W; Barna I; Puskár Z; Kozsurek M; Rónai AZ
    Eur J Pharmacol; 2011 Jan; 650(1):195-9. PubMed ID: 20940010
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Successful kinase bypass with new acyclovir phosphoramidate prodrugs.
    McGuigan C; Derudas M; Bugert JJ; Andrei G; Snoeck R; Balzarini J
    Bioorg Med Chem Lett; 2008 Aug; 18(15):4364-7. PubMed ID: 18614365
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Obligatory involvement of CD26/dipeptidyl peptidase IV in the activation of the antiretroviral tripeptide glycylprolylglycinamide (GPG-NH(2)).
    Balzarini J; Andersson E; Schols D; Proost P; Van Damme J; Svennerholm B; Horal P; Vahlne A
    Int J Biochem Cell Biol; 2004 Sep; 36(9):1848-59. PubMed ID: 15183349
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel dipeptide prodrugs of acyclovir for ocular herpes infections: Bioreversion, antiviral activity and transport across rabbit cornea.
    Anand B; Nashed Y; Mitra A
    Curr Eye Res; 2003; 26(3-4):151-63. PubMed ID: 12815543
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV.
    Namoto K; Sirockin F; Ostermann N; Gessier F; Flohr S; Sedrani R; Gerhartz B; Trappe J; Hassiepen U; Duttaroy A; Ferreira S; Sutton JM; Clark DE; Fenton G; Beswick M; Baeschlin DK
    Bioorg Med Chem Lett; 2014 Feb; 24(3):731-6. PubMed ID: 24439847
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.