BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 24192198)

  • 1. The glycogen phosphorylase inhibitor 2-(3-benzylamino-2-oxo-1,2-dihydropyridin-1-yl)-N-(3,4-dichlorobenzyl)acetamide.
    Popova I; Healy PC; Loughlin WA; Karis ND; Jenkins ID
    Acta Crystallogr C; 2013 Nov; 69(Pt 11):1408-10. PubMed ID: 24192198
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2-Oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors: Design, synthesis and structure-activity relationship study.
    Loughlin WA; Jenkins ID; Karis ND; Schweiker SS; Healy PC
    Eur J Med Chem; 2016 Mar; 111():1-14. PubMed ID: 26851835
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding.
    Alexacou KM; Hayes JM; Tiraidis C; Zographos SE; Leonidas DD; Chrysina ED; Archontis G; Oikonomakos NG; Paul JV; Varghese B; Loganathan D
    Proteins; 2008 May; 71(3):1307-23. PubMed ID: 18041758
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glycogen phosphorylase inhibitory effects of 2-oxo-1,2-dihydropyridin-3-yl amide derivatives.
    Karis ND; Loughlin WA; Jenkins ID; Healy PC
    Bioorg Med Chem; 2009 Jul; 17(13):4724-33. PubMed ID: 19443226
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Advances in glycogen phosphorylase inhibitor design.
    Oikonomakos NG; Somsák L
    Curr Opin Investig Drugs; 2008 Apr; 9(4):379-95. PubMed ID: 18393105
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol.
    Tsitsanou KE; Hayes JM; Keramioti M; Mamais M; Oikonomakos NG; Kato A; Leonidas DD; Zographos SE
    Food Chem Toxicol; 2013 Nov; 61():14-27. PubMed ID: 23279842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of new nanomolar inhibitors of GPa: Extension of 2-oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors.
    Loughlin WA; Jenkins ID; Karis ND; Healy PC
    Eur J Med Chem; 2017 Feb; 127():341-356. PubMed ID: 28076824
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.
    Chen J; Liu J; Zhang L; Wu G; Hua W; Wu X; Sun H
    Bioorg Med Chem Lett; 2006 Jun; 16(11):2915-9. PubMed ID: 16546381
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 2-Cyano-N-(4,6-dimethoxypyrimidin-2-yl)acetamide: complex sheets built from N-H...O and C-H...O hydrogen bonds.
    Gálvez JA; Quiroga J; Cobo J; Glidewell C
    Acta Crystallogr C; 2010 Oct; 66(Pt 10):o521-3. PubMed ID: 20921620
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A New Potent Inhibitor of Glycogen Phosphorylase Reveals the Basicity of the Catalytic Site.
    Mamais M; Degli Esposti A; Kouloumoundra V; Gustavsson T; Monti F; Venturini A; Chrysina ED; Markovitsi D; Gimisis T
    Chemistry; 2017 Jul; 23(37):8800-8805. PubMed ID: 28493496
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.
    Nagy V; Felföldi N; Kónya B; Praly JP; Docsa T; Gergely P; Chrysina ED; Tiraidis C; Kosmopoulou MN; Alexacou KM; Konstantakaki M; Leonidas DD; Zographos SE; Oikonomakos NG; Kozmon S; Tvaroška I; Somsák L
    Bioorg Med Chem; 2012 Mar; 20(5):1801-16. PubMed ID: 22325154
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-
    Fischer T; Koulas SM; Tsagkarakou AS; Kyriakis E; Stravodimos GA; Skamnaki VT; Liggri PGV; Zographos SE; Riedl R; Leonidas DD
    Molecules; 2019 Apr; 24(7):. PubMed ID: 30987252
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.
    Chen L; Li H; Liu J; Zhang L; Liu H; Jiang H
    Bioorg Med Chem; 2007 Nov; 15(21):6763-74. PubMed ID: 17719791
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of oleanolic acid dimers as inhibitors of glycogen phosphorylase.
    Cheng K; Liu J; Sun H; Xie J
    Chem Biodivers; 2010 Mar; 7(3):690-7. PubMed ID: 20232331
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Supramolecular structures in three thiouracil derivatives: 5,6-trimethylene-2-sulfanylidene-1,2-dihydropyrimidin-4(3H)-one, 2-(4-fluorobenzylsulfanyl)-5,6-trimethylenepyrimidin-4(3H)-one and methyl 2-{[2-(4-fluorobenzylsulfanyl)-5,6-trimethylenepyrimidin-4-yl]oxy}acetate.
    Zhou YJ; Lv J; Yu K; Ma JP; Guo DS
    Acta Crystallogr C Struct Chem; 2014 Apr; 70(Pt 4):416-20. PubMed ID: 24705060
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
    Oikonomakos NG; Tiraidis C; Leonidas DD; Zographos SE; Kristiansen M; Jessen CU; Nørskov-Lauritsen L; Agius L
    J Med Chem; 2006 Sep; 49(19):5687-701. PubMed ID: 16970395
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystallographic studies on N-azidoacetyl-beta-D-glucopyranosylamine, an inhibitor of glycogen phosphorylase: comparison with N-acetyl-beta-D-glucopyranosylamine.
    Petsalakis EI; Chrysina ED; Tiraidis C; Hadjiloi T; Leonidas DD; Oikonomakos NG; Aich U; Varghese B; Loganathan D
    Bioorg Med Chem; 2006 Aug; 14(15):5316-24. PubMed ID: 16616506
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 3-Cyano-6-hydroxy-4-methyl-2-pyridone: two new pseudopolymorphs and two cocrystals with products of an in situ nucleophilic aromatic substitution.
    Gerhardt V; Bolte M
    Acta Crystallogr C Struct Chem; 2015 Jan; 71(Pt 1):19-25. PubMed ID: 25567570
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
    Kantsadi AL; Bokor É; Kun S; Stravodimos GA; Chatzileontiadou DSM; Leonidas DD; Juhász-Tóth É; Szakács A; Batta G; Docsa T; Gergely P; Somsák L
    Eur J Med Chem; 2016 Nov; 123():737-745. PubMed ID: 27522507
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
    Watson KA; Chrysina ED; Tsitsanou KE; Zographos SE; Archontis G; Fleet GW; Oikonomakos NG
    Proteins; 2005 Dec; 61(4):966-83. PubMed ID: 16222658
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.