197 related articles for article (PubMed ID: 24194565)
1. OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.
Iusuf D; Ludwig M; Elbatsh A; van Esch A; van de Steeg E; Wagenaar E; van der Valk M; Lin F; van Tellingen O; Schinkel AH
Mol Cancer Ther; 2014 Feb; 13(2):492-503. PubMed ID: 24194565
[TBL] [Abstract][Full Text] [Related]
2. The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs: Insights from knockout and humanized mice.
Durmus S; van Hoppe S; Schinkel AH
Drug Resist Updat; 2016 Jul; 27():72-88. PubMed ID: 27449599
[TBL] [Abstract][Full Text] [Related]
3. In vivo disposition of doxorubicin is affected by mouse Oatp1a/1b and human OATP1A/1B transporters.
Durmus S; Naik J; Buil L; Wagenaar E; van Tellingen O; Schinkel AH
Int J Cancer; 2014 Oct; 135(7):1700-10. PubMed ID: 24554572
[TBL] [Abstract][Full Text] [Related]
4. Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.
Iusuf D; Hendrikx JJ; van Esch A; van de Steeg E; Wagenaar E; Rosing H; Beijnen JH; Schinkel AH
Int J Cancer; 2015 Jan; 136(1):225-33. PubMed ID: 24825069
[TBL] [Abstract][Full Text] [Related]
5. Influence of human OATP1B1, OATP1B3, and OATP1A2 on the pharmacokinetics of methotrexate and paclitaxel in humanized transgenic mice.
van de Steeg E; van Esch A; Wagenaar E; Kenworthy KE; Schinkel AH
Clin Cancer Res; 2013 Feb; 19(4):821-32. PubMed ID: 23243220
[TBL] [Abstract][Full Text] [Related]
6. Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.
Higgins JW; Bao JQ; Ke AB; Manro JR; Fallon JK; Smith PC; Zamek-Gliszczynski MJ
Drug Metab Dispos; 2014 Jan; 42(1):182-92. PubMed ID: 24194513
[TBL] [Abstract][Full Text] [Related]
7. Murine Oatp1a/1b uptake transporters control rosuvastatin systemic exposure without affecting its apparent liver exposure.
Iusuf D; van Esch A; Hobbs M; Taylor M; Kenworthy KE; van de Steeg E; Wagenaar E; Schinkel AH
Mol Pharmacol; 2013 May; 83(5):919-29. PubMed ID: 23429889
[TBL] [Abstract][Full Text] [Related]
8. Interplay of Ritonavir-Boosted Oral Cabazitaxel with the Organic Anion-Transporting Polypeptide (OATP) Uptake Transporters and Carboxylesterase 1 in Mice.
Loos NHC; Ferreira Martins ML; Rijmers J; de Jong D; Lebre MC; Tibben M; Beijnen JH; Schinkel AH
Mol Pharm; 2024 Apr; 21(4):1952-1964. PubMed ID: 38423793
[TBL] [Abstract][Full Text] [Related]
9. Organic anion-transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice.
Iusuf D; Sparidans RW; van Esch A; Hobbs M; Kenworthy KE; van de Steeg E; Wagenaar E; Beijnen JH; Schinkel AH
Mol Pharm; 2012 Sep; 9(9):2497-504. PubMed ID: 22812517
[TBL] [Abstract][Full Text] [Related]
10. Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.
Durmus S; Lozano-Mena G; van Esch A; Wagenaar E; van Tellingen O; Schinkel AH
Mol Pharm; 2015 Dec; 12(12):4259-69. PubMed ID: 26474710
[TBL] [Abstract][Full Text] [Related]
11. Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.
van de Steeg E; Wagenaar E; van der Kruijssen CM; Burggraaff JE; de Waart DR; Elferink RP; Kenworthy KE; Schinkel AH
J Clin Invest; 2010 Aug; 120(8):2942-52. PubMed ID: 20644253
[TBL] [Abstract][Full Text] [Related]
12. Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.
Lee HH; Leake BF; Kim RB; Ho RH
Mol Pharmacol; 2017 Jan; 91(1):14-24. PubMed ID: 27777271
[TBL] [Abstract][Full Text] [Related]
13. Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.
van de Steeg E; Stránecký V; Hartmannová H; Nosková L; Hřebíček M; Wagenaar E; van Esch A; de Waart DR; Oude Elferink RP; Kenworthy KE; Sticová E; al-Edreesi M; Knisely AS; Kmoch S; Jirsa M; Schinkel AH
J Clin Invest; 2012 Feb; 122(2):519-28. PubMed ID: 22232210
[TBL] [Abstract][Full Text] [Related]
14. Contribution of hepatic organic anion-transporting polypeptides to docetaxel uptake and clearance.
Lee HH; Leake BF; Teft W; Tirona RG; Kim RB; Ho RH
Mol Cancer Ther; 2015 Apr; 14(4):994-1003. PubMed ID: 25695959
[TBL] [Abstract][Full Text] [Related]
15. Human organic anion transporting polypeptide (OATP) 1B3 and mouse OATP1A/1B affect liver accumulation of Ochratoxin A in mice.
Wang J; Gan C; Qi X; Lebre MC; Schinkel AH
Toxicol Appl Pharmacol; 2020 Aug; 401():115072. PubMed ID: 32470353
[TBL] [Abstract][Full Text] [Related]
16. High impact of Oatp1a/1b transporters on in vivo disposition of the hydrophobic anticancer drug paclitaxel.
van de Steeg E; van Esch A; Wagenaar E; van der Kruijssen CM; van Tellingen O; Kenworthy KE; Schinkel AH
Clin Cancer Res; 2011 Jan; 17(2):294-301. PubMed ID: 21097690
[TBL] [Abstract][Full Text] [Related]
17. Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms.
Nozawa T; Minami H; Sugiura S; Tsuji A; Tamai I
Drug Metab Dispos; 2005 Mar; 33(3):434-9. PubMed ID: 15608127
[TBL] [Abstract][Full Text] [Related]
18. Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-transporting polypeptide 1B1 (SLCO1B1).
van de Steeg E; van der Kruijssen CM; Wagenaar E; Burggraaff JE; Mesman E; Kenworthy KE; Schinkel AH
Drug Metab Dispos; 2009 Feb; 37(2):277-81. PubMed ID: 19022939
[TBL] [Abstract][Full Text] [Related]
19. Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients.
Sai K; Saito Y; Tatewaki N; Hosokawa M; Kaniwa N; Nishimaki-Mogami T; Naito M; Sawada J; Shirao K; Hamaguchi T; Yamamoto N; Kunitoh H; Tamura T; Yamada Y; Ohe Y; Yoshida T; Minami H; Ohtsu A; Matsumura Y; Saijo N; Okuda H
Br J Clin Pharmacol; 2010 Aug; 70(2):222-33. PubMed ID: 20653675
[TBL] [Abstract][Full Text] [Related]
20. Direct inhibition and down-regulation by uremic plasma components of hepatic uptake transporter for SN-38, an active metabolite of irinotecan, in humans.
Fujita K; Sugiura T; Okumura H; Umeda S; Nakamichi N; Watanabe Y; Suzuki H; Sunakawa Y; Shimada K; Kawara K; Sasaki Y; Kato Y
Pharm Res; 2014 Jan; 31(1):204-15. PubMed ID: 23921491
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
