210 related articles for article (PubMed ID: 24196445)
1. Src kinase modulates the apoptotic p53 pathway by altering HIPK2 localization.
Polonio-Vallon T; Kirkpatrick J; Krijgsveld J; Hofmann TG
Cell Cycle; 2014; 13(1):115-25. PubMed ID: 24196445
[TBL] [Abstract][Full Text] [Related]
2. Zyxin is a critical regulator of the apoptotic HIPK2-p53 signaling axis.
Crone J; Glas C; Schultheiss K; Moehlenbrink J; Krieghoff-Henning E; Hofmann TG
Cancer Res; 2011 Mar; 71(6):2350-9. PubMed ID: 21248071
[TBL] [Abstract][Full Text] [Related]
3. The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage.
Reuven N; Adler J; Porat Z; Polonio-Vallon T; Hofmann TG; Shaul Y
J Biol Chem; 2015 Jul; 290(27):16478-88. PubMed ID: 25944899
[TBL] [Abstract][Full Text] [Related]
4. MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response.
Mancini F; Pieroni L; Monteleone V; Lucà R; Fici L; Luca E; Urbani A; Xiong S; Soddu S; Masetti R; Lozano G; Pontecorvi A; Moretti F
Oncogene; 2016 Jan; 35(2):228-40. PubMed ID: 25961923
[TBL] [Abstract][Full Text] [Related]
5. Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR.
Winter M; Sombroek D; Dauth I; Moehlenbrink J; Scheuermann K; Crone J; Hofmann TG
Nat Cell Biol; 2008 Jul; 10(7):812-24. PubMed ID: 18536714
[TBL] [Abstract][Full Text] [Related]
6. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.
D'Orazi G; Cecchinelli B; Bruno T; Manni I; Higashimoto Y; Saito S; Gostissa M; Coen S; Marchetti A; Del Sal G; Piaggio G; Fanciulli M; Appella E; Soddu S
Nat Cell Biol; 2002 Jan; 4(1):11-9. PubMed ID: 11780126
[TBL] [Abstract][Full Text] [Related]
7. Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis.
Di Stefano V; Rinaldo C; Sacchi A; Soddu S; D'Orazi G
Exp Cell Res; 2004 Feb; 293(2):311-20. PubMed ID: 14729469
[TBL] [Abstract][Full Text] [Related]
8. Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells.
Nardinocchi L; Puca R; Givol D; D'Orazi G
FEBS Lett; 2010 Oct; 584(19):4253-8. PubMed ID: 20849851
[TBL] [Abstract][Full Text] [Related]
9. HIPK2 modulates p53 activity towards pro-apoptotic transcription.
Puca R; Nardinocchi L; Sacchi A; Rechavi G; Givol D; D'Orazi G
Mol Cancer; 2009 Oct; 8():85. PubMed ID: 19828042
[TBL] [Abstract][Full Text] [Related]
10. HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations.
Di Stefano V; Mattiussi M; Sacchi A; D'Orazi G
FEBS Lett; 2005 Oct; 579(25):5473-80. PubMed ID: 16212962
[TBL] [Abstract][Full Text] [Related]
11. Hypoxia suppresses chemotherapeutic drug-induced p53 Serine 46 phosphorylation by triggering HIPK2 degradation.
Moehlenbrink J; Bitomsky N; Hofmann TG
Cancer Lett; 2010 Jun; 292(1):119-24. PubMed ID: 20018442
[TBL] [Abstract][Full Text] [Related]
12. Interplay between Mdm2 and HIPK2 in the DNA damage response.
Zhang XP; Liu F; Wang W
J R Soc Interface; 2014 Jul; 11(96):. PubMed ID: 24829283
[TBL] [Abstract][Full Text] [Related]
13. Cutaneous HPV23 E6 prevents p53 phosphorylation through interaction with HIPK2.
Muschik D; Braspenning-Wesch I; Stockfleth E; Rösl F; Hofmann TG; Nindl I
PLoS One; 2011; 6(11):e27655. PubMed ID: 22110707
[TBL] [Abstract][Full Text] [Related]
14. Role of the SUMO-interacting motif in HIPK2 targeting to the PML nuclear bodies and regulation of p53.
Sung KS; Lee YA; Kim ET; Lee SR; Ahn JH; Choi CY
Exp Cell Res; 2011 Apr; 317(7):1060-70. PubMed ID: 21192925
[TBL] [Abstract][Full Text] [Related]
15. The SIAH1-HIPK2-p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death.
He Y; Roos WP; Wu Q; Hofmann TG; Kaina B
Mol Cancer Res; 2019 May; 17(5):1129-1141. PubMed ID: 30796178
[TBL] [Abstract][Full Text] [Related]
16. Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2.
Hofmann TG; Möller A; Sirma H; Zentgraf H; Taya Y; Dröge W; Will H; Schmitz ML
Nat Cell Biol; 2002 Jan; 4(1):1-10. PubMed ID: 11740489
[TBL] [Abstract][Full Text] [Related]
17. Overexpression of HIPK2 circumvents the blockade of apoptosis in chemoresistant ovarian cancer cells.
Puca R; Nardinocchi L; Pistritto G; D'Orazi G
Gynecol Oncol; 2008 Jun; 109(3):403-10. PubMed ID: 18395248
[TBL] [Abstract][Full Text] [Related]
18. Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation.
Rui Y; Xu Z; Lin S; Li Q; Rui H; Luo W; Zhou HM; Cheung PY; Wu Z; Ye Z; Li P; Han J; Lin SC
EMBO J; 2004 Nov; 23(23):4583-94. PubMed ID: 15526030
[TBL] [Abstract][Full Text] [Related]
19. HIPK2-a therapeutical target to be (re)activated for tumor suppression: role in p53 activation and HIF-1α inhibition.
Nardinocchi L; Puca R; Givol D; D'Orazi G
Cell Cycle; 2010 Apr; 9(7):1270-5. PubMed ID: 20234185
[TBL] [Abstract][Full Text] [Related]
20. Homeodomain-interacting protein kinase 2 is the ionizing radiation-activated p53 serine 46 kinase and is regulated by ATM.
Dauth I; Krüger J; Hofmann TG
Cancer Res; 2007 Mar; 67(5):2274-9. PubMed ID: 17332358
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]