BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 24198241)

  • 1. The ATP-competitive mTOR inhibitor INK128 enhances in vitro and in vivo radiosensitivity of pancreatic carcinoma cells.
    Hayman TJ; Wahba A; Rath BH; Bae H; Kramp T; Shankavaram UT; Camphausen K; Tofilon PJ
    Clin Cancer Res; 2014 Jan; 20(1):110-9. PubMed ID: 24198241
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The novel mTORC1/2 dual inhibitor INK128 enhances radiosensitivity of breast cancer cell line MCF-7.
    Liu ZG; Tang J; Chen Z; Zhang H; Wang H; Yang J; Zhang H
    Int J Oncol; 2016 Sep; 49(3):1039-45. PubMed ID: 27574017
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The mTORC1/mTORC2 inhibitor AZD2014 enhances the radiosensitivity of glioblastoma stem-like cells.
    Kahn J; Hayman TJ; Jamal M; Rath BH; Kramp T; Camphausen K; Tofilon PJ
    Neuro Oncol; 2014 Jan; 16(1):29-37. PubMed ID: 24311635
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Radiation Enhancement of Head and Neck Squamous Cell Carcinoma by the Dual PI3K/mTOR Inhibitor PF-05212384.
    Leiker AJ; DeGraff W; Choudhuri R; Sowers AL; Thetford A; Cook JA; Van Waes C; Mitchell JB
    Clin Cancer Res; 2015 Jun; 21(12):2792-801. PubMed ID: 25724523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mTOR ATP-competitive inhibitor INK128 inhibits neuroblastoma growth via blocking mTORC signaling.
    Zhang H; Dou J; Yu Y; Zhao Y; Fan Y; Cheng J; Xu X; Liu W; Guan S; Chen Z; shi Y; Patel R; Vasudevan SA; Zage PE; Zhang H; Nuchtern JG; Kim ES; Fu S; Yang J
    Apoptosis; 2015 Jan; 20(1):50-62. PubMed ID: 25425103
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma.
    Mazan-Mamczarz K; Peroutka RJ; Steinhardt JJ; Gidoni M; Zhang Y; Lehrmann E; Landon AL; Dai B; Houng S; Muniandy PA; Efroni S; Becker KG; Gartenhaus RB
    Cell Commun Signal; 2015 Mar; 13():15. PubMed ID: 25849580
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma.
    Miyahara H; Yadavilli S; Natsumeda M; Rubens JA; Rodgers L; Kambhampati M; Taylor IC; Kaur H; Asnaghi L; Eberhart CG; Warren KE; Nazarian J; Raabe EH
    Cancer Lett; 2017 Aug; 400():110-116. PubMed ID: 28450157
    [TBL] [Abstract][Full Text] [Related]  

  • 8. AZD5438, an inhibitor of Cdk1, 2, and 9, enhances the radiosensitivity of non-small cell lung carcinoma cells.
    Raghavan P; Tumati V; Yu L; Chan N; Tomimatsu N; Burma S; Bristow RG; Saha D
    Int J Radiat Oncol Biol Phys; 2012 Nov; 84(4):e507-14. PubMed ID: 22795803
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of the Translation Initiation Factor eIF4A Enhances Tumor Cell Radiosensitivity.
    Lehman SL; Wechsler T; Schwartz K; Brown LE; Porco JA; Devine WG; Pelletier J; Shankavaram UT; Camphausen K; Tofilon PJ
    Mol Cancer Ther; 2022 Sep; 21(9):1406-1414. PubMed ID: 35732578
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer.
    Chen YH; Wei MF; Wang CW; Lee HW; Pan SL; Gao M; Kuo SH; Cheng AL; Teng CM
    Cancer Lett; 2015 Feb; 357(2):582-90. PubMed ID: 25497009
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Competitive but Not Allosteric mTOR Kinase Inhibition Enhances Tumor Cell Radiosensitivity.
    Hayman TJ; Kramp T; Kahn J; Jamal M; Camphausen K; Tofilon PJ
    Transl Oncol; 2013 Jun; 6(3):355-62. PubMed ID: 23730416
    [TBL] [Abstract][Full Text] [Related]  

  • 12. mTOR inhibitor INK128 attenuates dextran sodium sulfate-induced colitis by promotion of MDSCs on Treg cell expansion.
    Shi G; Li D; Ren J; Li X; Wang T; Dou H; Hou Y
    J Cell Physiol; 2019 Feb; 234(2):1618-1629. PubMed ID: 30132862
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Co-administration of the mTORC1/TORC2 inhibitor INK128 and the Bcl-2/Bcl-xL antagonist ABT-737 kills human myeloid leukemia cells through Mcl-1 down-regulation and AKT inactivation.
    Rahmani M; Aust MM; Hawkins E; Parker RE; Ross M; Kmieciak M; Reshko LB; Rizzo KA; Dumur CI; Ferreira-Gonzalez A; Grant S
    Haematologica; 2015 Dec; 100(12):1553-63. PubMed ID: 26452980
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The DNA-PK Inhibitor VX-984 Enhances the Radiosensitivity of Glioblastoma Cells Grown
    Timme CR; Rath BH; O'Neill JW; Camphausen K; Tofilon PJ
    Mol Cancer Ther; 2018 Jun; 17(6):1207-1216. PubMed ID: 29549168
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual PI3K/mTOR inhibitors, GSK2126458 and PKI-587, suppress tumor progression and increase radiosensitivity in nasopharyngeal carcinoma.
    Liu T; Sun Q; Li Q; Yang H; Zhang Y; Wang R; Lin X; Xiao D; Yuan Y; Chen L; Wang W
    Mol Cancer Ther; 2015 Feb; 14(2):429-39. PubMed ID: 25504751
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeted inhibition of mammalian target of rapamycin (mTOR) enhances radiosensitivity in pancreatic carcinoma cells.
    Dai ZJ; Gao J; Kang HF; Ma YG; Ma XB; Lu WF; Lin S; Ma HB; Wang XJ; Wu WY
    Drug Des Devel Ther; 2013; 7():149-59. PubMed ID: 23662044
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The second-generation mTOR kinase inhibitor INK128 exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW 264.7 cells.
    Pan H; Xu LH; Ouyang DY; Wang Y; Zha QB; Hou XF; He XH
    Inflammation; 2014 Jun; 37(3):756-65. PubMed ID: 24385238
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mTOR Kinase Inhibitor INK128 Blunts Migration of Cultured Retinal Pigment Epithelial Cells.
    Calton MA; Vollrath D
    Adv Exp Med Biol; 2016; 854():709-15. PubMed ID: 26427479
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice.
    Heredia A; Le N; Gartenhaus RB; Sausville E; Medina-Moreno S; Zapata JC; Davis C; Gallo RC; Redfield RR
    Proc Natl Acad Sci U S A; 2015 Jul; 112(30):9412-7. PubMed ID: 26170311
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer.
    Mrozek EM; Bajaj V; Guo Y; Malinowska IA; Zhang J; Kwiatkowski DJ
    PLoS One; 2021; 16(4):e0248380. PubMed ID: 33891611
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.