BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 24206264)

  • 1. Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes.
    Clerc P; Ge SX; Hwang H; Waddell J; Roelofs BA; Karbowski M; Sesaki H; Polster BM
    Br J Pharmacol; 2014 Apr; 171(8):1988-99. PubMed ID: 24206264
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rapid detection of an ABT-737-sensitive primed for death state in cells using microplate-based respirometry.
    Clerc P; Carey GB; Mehrabian Z; Wei M; Hwang H; Girnun GD; Chen H; Martin SS; Polster BM
    PLoS One; 2012; 7(8):e42487. PubMed ID: 22880001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A; Brady NR
    J Biol Chem; 2015 Sep; 290(36):22005-18. PubMed ID: 26134559
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak.
    Lindqvist LM; Heinlein M; Huang DC; Vaux DL
    Proc Natl Acad Sci U S A; 2014 Jun; 111(23):8512-7. PubMed ID: 24912196
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.
    Chen S; Dai Y; Harada H; Dent P; Grant S
    Cancer Res; 2007 Jan; 67(2):782-91. PubMed ID: 17234790
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BH3-only protein bid participates in the Bcl-2 network in healthy liver cells.
    Hikita H; Takehara T; Kodama T; Shimizu S; Hosui A; Miyagi T; Tatsumi T; Ishida H; Ohkawa K; Li W; Kanto T; Hiramatsu N; Hennighausen L; Yin XM; Hayashi N
    Hepatology; 2009 Dec; 50(6):1972-80. PubMed ID: 19839062
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress.
    Oettinghaus B; D'Alonzo D; Barbieri E; Restelli LM; Savoia C; Licci M; Tolnay M; Frank S; Scorrano L
    Biochim Biophys Acta; 2016 Aug; 1857(8):1267-1276. PubMed ID: 26997499
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J; Huang K; O'Neill KL; Pang X; Luo X
    Cell Death Dis; 2016 Jun; 7(6):e2266. PubMed ID: 27310874
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L).
    Lindenboim L; Blacher E; Borner C; Stein R
    Cell Death Differ; 2010 Feb; 17(2):346-59. PubMed ID: 19816507
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
    Rahmani M; Aust MM; Attkisson E; Williams DC; Ferreira-Gonzalez A; Grant S
    Cancer Res; 2013 Feb; 73(4):1340-51. PubMed ID: 23243017
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of phosphatidylinositol 3-kinase/AKT signaling by NVP-BKM120 promotes ABT-737-induced toxicity in a caspase-dependent manner through mitochondrial dysfunction and DNA damage response in established and primary cultured glioblastoma cells.
    Jane EP; Premkumar DR; Morales A; Foster KA; Pollack IF
    J Pharmacol Exp Ther; 2014 Jul; 350(1):22-35. PubMed ID: 24741074
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.
    van Delft MF; Wei AH; Mason KD; Vandenberg CJ; Chen L; Czabotar PE; Willis SN; Scott CL; Day CL; Cory S; Adams JM; Roberts AW; Huang DC
    Cancer Cell; 2006 Nov; 10(5):389-99. PubMed ID: 17097561
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent.
    Choi S; Singh SV
    Cancer Res; 2005 Mar; 65(5):2035-43. PubMed ID: 15753404
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737.
    Sutton VR; Sedelies K; Dewson G; Christensen ME; Bird PI; Johnstone RW; Kluck RM; Trapani JA; Waterhouse NJ
    Cell Death Dis; 2012 Jul; 3(7):e344. PubMed ID: 22764103
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species.
    Bordt EA; Clerc P; Roelofs BA; Saladino AJ; Tretter L; Adam-Vizi V; Cherok E; Khalil A; Yadava N; Ge SX; Francis TC; Kennedy NW; Picton LK; Kumar T; Uppuluri S; Miller AM; Itoh K; Karbowski M; Sesaki H; Hill RB; Polster BM
    Dev Cell; 2017 Mar; 40(6):583-594.e6. PubMed ID: 28350990
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets.
    Kodama T; Takehara T; Hikita H; Shimizu S; Shigekawa M; Li W; Miyagi T; Hosui A; Tatsumi T; Ishida H; Kanto T; Hiramatsu N; Yin XM; Hayashi N
    J Biol Chem; 2011 Apr; 286(16):13905-13. PubMed ID: 21367852
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells.
    Huang S; Sinicrope FA
    Cancer Res; 2008 Apr; 68(8):2944-51. PubMed ID: 18413764
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapy.
    Yamaguchi R; Janssen E; Perkins G; Ellisman M; Kitada S; Reed JC
    PLoS One; 2011; 6(9):e24102. PubMed ID: 21949692
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Different forms of cell death induced by putative BCL2 inhibitors.
    Vogler M; Weber K; Dinsdale D; Schmitz I; Schulze-Osthoff K; Dyer MJ; Cohen GM
    Cell Death Differ; 2009 Jul; 16(7):1030-9. PubMed ID: 19390557
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K; Srinivasula SM; Alnemri ES; Thompson CB; Korsmeyer SJ; Bryant JL; Srivastava RK
    Cancer Res; 2003 Apr; 63(7):1712-21. PubMed ID: 12670926
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.