These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 24211022)

  • 1. Discovery of a potent respiratory syncytial virus RNA polymerase inhibitor.
    Xiong H; Foulk M; Aschenbrenner L; Fan J; Tiong-Yip CL; Johnson KD; Moustakas D; Fleming PR; Brown DG; Zhang M; Ferguson D; Wu D; Yu Q
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6789-93. PubMed ID: 24211022
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of novel benzothienoazepine derivatives as potent inhibitors of respiratory syncytial virus.
    Fordyce EAF; Brookes DW; Lise-Ciana C; Coates MS; Hunt SF; Ito K; King-Underwood J; Onions ST; Parra GF; Rapeport G; Sherbukhin V; Stockwell JA; Strong P; Thomas JC; Murray J
    Bioorg Med Chem Lett; 2017 May; 27(10):2201-2206. PubMed ID: 28372911
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of 4'-chloromethyl-2'-deoxy-3',5'-di-O-isobutyryl-2'-fluorocytidine (ALS-8176), a first-in-class RSV polymerase inhibitor for treatment of human respiratory syncytial virus infection.
    Wang G; Deval J; Hong J; Dyatkina N; Prhavc M; Taylor J; Fung A; Jin Z; Stevens SK; Serebryany V; Liu J; Zhang Q; Tam Y; Chanda SM; Smith DB; Symons JA; Blatt LM; Beigelman L
    J Med Chem; 2015 Feb; 58(4):1862-78. PubMed ID: 25667954
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of β-D-2'-deoxy-2'-α-fluoro-4'-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases.
    Clarke MO; Mackman R; Byun D; Hui H; Barauskas O; Birkus G; Chun BK; Doerffler E; Feng J; Karki K; Lee G; Perron M; Siegel D; Swaminathan S; Lee W
    Bioorg Med Chem Lett; 2015 Jun; 25(12):2484-7. PubMed ID: 25978965
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Respiratory Syncytial Virus Inhibitor AZ-27 Differentially Inhibits Different Polymerase Activities at the Promoter.
    Noton SL; Nagendra K; Dunn EF; Mawhorter ME; Yu Q; Fearns R
    J Virol; 2015 Aug; 89(15):7786-98. PubMed ID: 25995255
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substrate/inhibition studies of bacteriophage T7 RNA polymerase with the 5'-triphosphate derivative of a ring-expanded ('fat') nucleoside possessing potent antiviral and anticancer activities.
    Bretner M; Beckett TD; Sood RK; Baldisseri DM; Hosmane RS
    Bioorg Med Chem; 1999 Dec; 7(12):2931-6. PubMed ID: 10658598
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Direct Inhibition of Cellular Fatty Acid Synthase Impairs Replication of Respiratory Syncytial Virus and Other Respiratory Viruses.
    Ohol YM; Wang Z; Kemble G; Duke G
    PLoS One; 2015; 10(12):e0144648. PubMed ID: 26659560
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The fight against the influenza A virus H1N1: synthesis, molecular modeling, and biological evaluation of benzofurazan derivatives as viral RNA polymerase inhibitors.
    Pagano M; Castagnolo D; Bernardini M; Fallacara AL; Laurenzana I; Deodato D; Kessler U; Pilger B; Stergiou L; Strunze S; Tintori C; Botta M
    ChemMedChem; 2014 Jan; 9(1):129-50. PubMed ID: 24285596
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase.
    Liuzzi M; Mason SW; Cartier M; Lawetz C; McCollum RS; Dansereau N; Bolger G; Lapeyre N; Gaudette Y; Lagacé L; Massariol MJ; Dô F; Whitehead P; Lamarre L; Scouten E; Bordeleau J; Landry S; Rancourt J; Fazal G; Simoneau B
    J Virol; 2005 Oct; 79(20):13105-15. PubMed ID: 16189012
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of Non-Nucleoside Inhibitors of the Respiratory Syncytial Virus Polymerase Complex.
    Jiménez-Somarribas A; Mao S; Yoon JJ; Weisshaar M; Cox RM; Marengo JR; Mitchell DG; Morehouse ZP; Yan D; Solis I; Liotta DC; Natchus MG; Plemper RK
    J Med Chem; 2017 Mar; 60(6):2305-2325. PubMed ID: 28245119
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of pyrimidine nucleoside monophosphate prodrugs targeted against influenza virus.
    Meneghesso S; Vanderlinden E; Stevaert A; McGuigan C; Balzarini J; Naesens L
    Antiviral Res; 2012 Apr; 94(1):35-43. PubMed ID: 22306172
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two novel fusion inhibitors of human respiratory syncytial virus.
    Lundin A; Bergström T; Bendrioua L; Kann N; Adamiak B; Trybala E
    Antiviral Res; 2010 Dec; 88(3):317-24. PubMed ID: 20965215
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery and synthesis of novel benzofurazan derivatives as inhibitors of influenza A virus.
    Kessler U; Castagnolo D; Pagano M; Deodato D; Bernardini M; Pilger B; Ranadheera C; Botta M
    Bioorg Med Chem Lett; 2013 Oct; 23(20):5575-7. PubMed ID: 24012120
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of 2'-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase.
    Parrish JP; Lee SK; Boojamra CG; Hui H; Babusis D; Brown B; Shih IH; Feng JY; Ray AS; Mackman RL
    Bioorg Med Chem Lett; 2013 Jun; 23(11):3354-7. PubMed ID: 23639543
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Drug candidates and model systems in respiratory syncytial virus antiviral drug discovery.
    Heylen E; Neyts J; Jochmans D
    Biochem Pharmacol; 2017 Mar; 127():1-12. PubMed ID: 27659812
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New antiviral approaches for respiratory syncytial virus and other mononegaviruses: Inhibiting the RNA polymerase.
    Fearns R; Deval J
    Antiviral Res; 2016 Oct; 134():63-76. PubMed ID: 27575793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir.
    Tchesnokov EP; Feng JY; Porter DP; Götte M
    Viruses; 2019 Apr; 11(4):. PubMed ID: 30987343
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate.
    Deval J; Hong J; Wang G; Taylor J; Smith LK; Fung A; Stevens SK; Liu H; Jin Z; Dyatkina N; Prhavc M; Stoycheva AD; Serebryany V; Liu J; Smith DB; Tam Y; Zhang Q; Moore ML; Fearns R; Chanda SM; Blatt LM; Symons JA; Beigelman L
    PLoS Pathog; 2015 Jun; 11(6):e1004995. PubMed ID: 26098424
    [TBL] [Abstract][Full Text] [Related]  

  • 19. YM-53403, a unique anti-respiratory syncytial virus agent with a novel mechanism of action.
    Sudo K; Miyazaki Y; Kojima N; Kobayashi M; Suzuki H; Shintani M; Shimizu Y
    Antiviral Res; 2005 Feb; 65(2):125-31. PubMed ID: 15708639
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rational design of polymerase inhibitors as antiviral drugs.
    Oberg B
    Antiviral Res; 2006 Sep; 71(2-3):90-5. PubMed ID: 16820225
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.