190 related articles for article (PubMed ID: 24213570)
1. Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis.
Tan M; Li H; Sun Y
Oncogene; 2014 Oct; 33(44):5211-20. PubMed ID: 24213570
[TBL] [Abstract][Full Text] [Related]
2. Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axis.
Tan M; Xu J; Siddiqui J; Feng F; Sun Y
Mol Cancer; 2016 Dec; 15(1):81. PubMed ID: 27955654
[TBL] [Abstract][Full Text] [Related]
3. Inactivation of SAG E3 ubiquitin ligase blocks embryonic stem cell differentiation and sensitizes leukemia cells to retinoid acid.
Tan M; Li Y; Yang R; Xi N; Sun Y
PLoS One; 2011; 6(11):e27726. PubMed ID: 22110742
[TBL] [Abstract][Full Text] [Related]
4. Suppression of tumor angiogenesis by targeting the protein neddylation pathway.
Yao WT; Wu JF; Yu GY; Wang R; Wang K; Li LH; Chen P; Jiang YN; Cheng H; Lee HW; Yu J; Qi H; Yu XJ; Wang P; Chu YW; Yang M; Hua ZC; Ying HQ; Hoffman RM; Jeong LS; Jia LJ
Cell Death Dis; 2014 Feb; 5(2):e1059. PubMed ID: 24525735
[TBL] [Abstract][Full Text] [Related]
5. Inactivation of Sag/Rbx2/Roc2 e3 ubiquitin ligase triggers senescence and inhibits kras-induced immortalization.
Tan M; Li H; Sun Y
Neoplasia; 2015 Jan; 17(1):114-23. PubMed ID: 25622904
[TBL] [Abstract][Full Text] [Related]
6. SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation.
Tan M; Zhao Y; Kim SJ; Liu M; Jia L; Saunders TL; Zhu Y; Sun Y
Dev Cell; 2011 Dec; 21(6):1062-76. PubMed ID: 22118770
[TBL] [Abstract][Full Text] [Related]
7. Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
Lan H; Tang Z; Jin H; Sun Y
Sci Rep; 2016 Apr; 6():24218. PubMed ID: 27063292
[TBL] [Abstract][Full Text] [Related]
8. Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells.
Luo Z; Pan Y; Jeong LS; Liu J; Jia L
Autophagy; 2012 Nov; 8(11):1677-9. PubMed ID: 22874562
[TBL] [Abstract][Full Text] [Related]
9. Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis.
Li H; Tan M; Jia L; Wei D; Zhao Y; Chen G; Xu J; Zhao L; Thomas D; Beer DG; Sun Y
J Clin Invest; 2014 Feb; 124(2):835-46. PubMed ID: 24430184
[TBL] [Abstract][Full Text] [Related]
10. Functional characterization of SAG/RBX2/ROC2/RNF7, an antioxidant protein and an E3 ubiquitin ligase.
Sun Y; Li H
Protein Cell; 2013 Feb; 4(2):103-16. PubMed ID: 23136067
[TBL] [Abstract][Full Text] [Related]
11. Induction of p21-dependent senescence by an NAE inhibitor, MLN4924, as a mechanism of growth suppression.
Jia L; Li H; Sun Y
Neoplasia; 2011 Jun; 13(6):561-9. PubMed ID: 21677879
[TBL] [Abstract][Full Text] [Related]
12. SAG/Rbx2-Dependent Neddylation Regulates T-Cell Responses.
Mathewson ND; Fujiwara H; Wu SR; Toubai T; Oravecz-Wilson K; Sun Y; Rossi C; Zajac C; Sun Y; Reddy P
Am J Pathol; 2016 Oct; 186(10):2679-91. PubMed ID: 27543965
[TBL] [Abstract][Full Text] [Related]
13. Overactivated neddylation pathway as a therapeutic target in lung cancer.
Li L; Wang M; Yu G; Chen P; Li H; Wei D; Zhu J; Xie L; Jia H; Shi J; Li C; Yao W; Wang Y; Gao Q; Jeong LS; Lee HW; Yu J; Hu F; Mei J; Wang P; Chu Y; Qi H; Yang M; Dong Z; Sun Y; Hoffman RM; Jia L
J Natl Cancer Inst; 2014 Jun; 106(6):dju083. PubMed ID: 24853380
[TBL] [Abstract][Full Text] [Related]
14. Sag/Rbx2 Partial Inactivation Sensitizes Mice to Radiation and Radiation-Induced Tumorigenesis1.
Sun Y; Li H; Tan M; Sun Y
Radiat Res; 2023 Mar; 199(3):273-282. PubMed ID: 36745565
[TBL] [Abstract][Full Text] [Related]
15. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis.
Xie CM; Wei D; Zhao L; Marchetto S; Mei L; Borg JP; Sun Y
J Cell Biol; 2015 Jun; 209(5):721-37. PubMed ID: 26056141
[TBL] [Abstract][Full Text] [Related]
16. Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells.
Wang Y; Luo Z; Pan Y; Wang W; Zhou X; Jeong LS; Chu Y; Liu J; Jia L
Cancer Biol Ther; 2015; 16(3):420-9. PubMed ID: 25782162
[TBL] [Abstract][Full Text] [Related]
17. Validation of SAG/RBX2/ROC2 E3 ubiquitin ligase as an anticancer and radiosensitizing target.
Jia L; Yang J; Hao X; Zheng M; He H; Xiong X; Xu L; Sun Y
Clin Cancer Res; 2010 Feb; 16(3):814-24. PubMed ID: 20103673
[TBL] [Abstract][Full Text] [Related]
18. Ubiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancer.
Pan WW; Zhou JJ; Yu C; Xu Y; Guo LJ; Zhang HY; Zhou D; Song FZ; Fan HY
J Biol Chem; 2013 Oct; 288(41):29680-91. PubMed ID: 23995842
[TBL] [Abstract][Full Text] [Related]
19. Promotion of S-phase entry and cell growth under serum starvation by SAG/ROC2/Rbx2/Hrt2, an E3 ubiquitin ligase component: association with inhibition of p27 accumulation.
Duan H; Tsvetkov LM; Liu Y; Song Y; Swaroop M; Wen R; Kung HF; Zhang H; Sun Y
Mol Carcinog; 2001 Jan; 30(1):37-46. PubMed ID: 11255262
[TBL] [Abstract][Full Text] [Related]
20. SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-O-tetradecanoylphorbol-13-acetate-induced neoplastic transformation.
Gu Q; Tan M; Sun Y
Cancer Res; 2007 Apr; 67(8):3616-25. PubMed ID: 17440073
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]