144 related articles for article (PubMed ID: 24217025)
1. The E280A presenilin mutation reduces voltage-gated sodium channel levels in neuronal cells.
Kim DY; Wertz MH; Gautam V; D'Avanzo C; Bhattacharyya R; Kovacs DM
Neurodegener Dis; 2014; 13(2-3):64-68. PubMed ID: 24217025
[TBL] [Abstract][Full Text] [Related]
2. Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease.
Corbett BF; Leiser SC; Ling HP; Nagy R; Breysse N; Zhang X; Hazra A; Brown JT; Randall AD; Wood A; Pangalos MN; Reinhart PH; Chin J
J Neurosci; 2013 Apr; 33(16):7020-6. PubMed ID: 23595759
[TBL] [Abstract][Full Text] [Related]
3. Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration.
Kim DY; Ingano LA; Carey BW; Pettingell WH; Kovacs DM
J Biol Chem; 2005 Jun; 280(24):23251-61. PubMed ID: 15833746
[TBL] [Abstract][Full Text] [Related]
4. BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels.
Sachse CC; Kim YH; Agsten M; Huth T; Alzheimer C; Kovacs DM; Kim DY
FASEB J; 2013 Jun; 27(6):2458-67. PubMed ID: 23504710
[TBL] [Abstract][Full Text] [Related]
5. Navβ2 knockdown improves cognition in APP/PS1 mice by partially inhibiting seizures and APP amyloid processing.
Hu T; Xiao Z; Mao R; Chen B; Lu MN; Tong J; Mei R; Li SS; Xiao ZC; Zhang LF; Xiyang YB
Oncotarget; 2017 Nov; 8(59):99284-99295. PubMed ID: 29245901
[TBL] [Abstract][Full Text] [Related]
6. Presenilin/γ-secretase regulates neurexin processing at synapses.
Saura CA; Servián-Morilla E; Scholl FG
PLoS One; 2011 Apr; 6(4):e19430. PubMed ID: 21559374
[TBL] [Abstract][Full Text] [Related]
7. Three-amino acid spacing of presenilin endoproteolysis suggests a general stepwise cleavage of gamma-secretase-mediated intramembrane proteolysis.
Fukumori A; Fluhrer R; Steiner H; Haass C
J Neurosci; 2010 Jun; 30(23):7853-62. PubMed ID: 20534834
[TBL] [Abstract][Full Text] [Related]
8. Neuroprotection induced by Navβ2‑knockdown in APP/PS1 transgenic neurons is associated with NEP regulation.
Hu T; Li SS; Lu MN; Zhang L; Chen B; Mao R; Mei R; Tan YX; Li S; Xiyang YB
Mol Med Rep; 2019 Aug; 20(2):2002-2011. PubMed ID: 31257483
[TBL] [Abstract][Full Text] [Related]
9. Alzheimer's disease-linked mutations in presenilin-1 result in a drastic loss of activity in purified γ-secretase complexes.
Cacquevel M; Aeschbach L; Houacine J; Fraering PC
PLoS One; 2012; 7(4):e35133. PubMed ID: 22529981
[TBL] [Abstract][Full Text] [Related]
10. Familial Alzheimer's disease mutations in presenilins: effects on endoplasmic reticulum calcium homeostasis and correlation with clinical phenotypes.
Nelson O; Supnet C; Liu H; Bezprozvanny I
J Alzheimers Dis; 2010; 21(3):781-93. PubMed ID: 20634584
[TBL] [Abstract][Full Text] [Related]
11. Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit.
Gersbacher MT; Kim DY; Bhattacharyya R; Kovacs DM
Mol Neurodegener; 2010 Dec; 5():61. PubMed ID: 21182789
[TBL] [Abstract][Full Text] [Related]
12. The presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells.
Woodruff G; Young JE; Martinez FJ; Buen F; Gore A; Kinaga J; Li Z; Yuan SH; Zhang K; Goldstein LS
Cell Rep; 2013 Nov; 5(4):974-85. PubMed ID: 24239350
[TBL] [Abstract][Full Text] [Related]
13. Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry.
Tong BC; Lee CS; Cheng WH; Lai KO; Foskett JK; Cheung KH
Sci Signal; 2016 Sep; 9(444):ra89. PubMed ID: 27601731
[TBL] [Abstract][Full Text] [Related]
14. Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons.
Cheung KH; Mei L; Mak DO; Hayashi I; Iwatsubo T; Kang DE; Foskett JK
Sci Signal; 2010 Mar; 3(114):ra22. PubMed ID: 20332427
[TBL] [Abstract][Full Text] [Related]
15. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
Zatti G; Burgo A; Giacomello M; Barbiero L; Ghidoni R; Sinigaglia G; Florean C; Bagnoli S; Binetti G; Sorbi S; Pizzo P; Fasolato C
Cell Calcium; 2006 Jun; 39(6):539-50. PubMed ID: 16620965
[TBL] [Abstract][Full Text] [Related]
16. Generation of Abeta38 and Abeta42 is independently and differentially affected by familial Alzheimer disease-associated presenilin mutations and gamma-secretase modulation.
Page RM; Baumann K; Tomioka M; Pérez-Revuelta BI; Fukumori A; Jacobsen H; Flohr A; Luebbers T; Ozmen L; Steiner H; Haass C
J Biol Chem; 2008 Jan; 283(2):677-83. PubMed ID: 17962197
[TBL] [Abstract][Full Text] [Related]
17. Familial Alzheimer's disease presenilin 1 mutations cause alterations in the conformation of presenilin and interactions with amyloid precursor protein.
Berezovska O; Lleo A; Herl LD; Frosch MP; Stern EA; Bacskai BJ; Hyman BT
J Neurosci; 2005 Mar; 25(11):3009-17. PubMed ID: 15772361
[TBL] [Abstract][Full Text] [Related]
18. A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations.
Marambaud P; Wen PH; Dutt A; Shioi J; Takashima A; Siman R; Robakis NK
Cell; 2003 Sep; 114(5):635-45. PubMed ID: 13678586
[TBL] [Abstract][Full Text] [Related]
19. Major carboxyl terminal fragments generated by γ-secretase processing of the Alzheimer amyloid precursor are 50 and 51 amino acids long.
Pinnix I; Ghiso JA; Pappolla MA; Sambamurti K
Am J Geriatr Psychiatry; 2013 May; 21(5):474-83. PubMed ID: 23570890
[TBL] [Abstract][Full Text] [Related]
20. Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1).
Kuzuya A; Uemura K; Kitagawa N; Aoyagi N; Kihara T; Ninomiya H; Ishiura S; Takahashi R; Shimohama S
J Neurosci Res; 2007 Jan; 85(1):153-65. PubMed ID: 17075903
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]