264 related articles for article (PubMed ID: 24218150)
1. Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes.
Sueyoshi T; Li L; Wang H; Moore R; Kodavanti PR; Lehmler HJ; Negishi M; Birnbaum LS
Toxicol Sci; 2014 Feb; 137(2):292-302. PubMed ID: 24218150
[TBL] [Abstract][Full Text] [Related]
2. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
3. Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors.
Paul KB; Thompson JT; Simmons SO; Vanden Heuvel JP; Crofton KM
Toxicol In Vitro; 2013 Oct; 27(7):2049-60. PubMed ID: 23899473
[TBL] [Abstract][Full Text] [Related]
4. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
[TBL] [Abstract][Full Text] [Related]
5. Toxaphene-induced mouse liver tumorigenesis is mediated by the constitutive androstane receptor.
Wang Z; Li X; Wu Q; Lamb JC; Klaunig JE
J Appl Toxicol; 2017 Aug; 37(8):967-975. PubMed ID: 28218408
[TBL] [Abstract][Full Text] [Related]
6. The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators.
Pacyniak EK; Cheng X; Cunningham ML; Crofton K; Klaassen CD; Guo GL
Toxicol Sci; 2007 May; 97(1):94-102. PubMed ID: 17324954
[TBL] [Abstract][Full Text] [Related]
7. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
Hoffart E; Ghebreghiorghis L; Nussler AK; Thasler WE; Weiss TS; Schwab M; Burk O
Br J Pharmacol; 2012 Mar; 165(5):1595-608. PubMed ID: 21913896
[TBL] [Abstract][Full Text] [Related]
8. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
Kanno Y; Tanuma N; Yazawa S; Zhao S; Inaba M; Nakamura S; Nemoto K; Inouye Y
Drug Metab Dispos; 2016 Aug; 44(8):1158-63. PubMed ID: 27197997
[TBL] [Abstract][Full Text] [Related]
9. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
[TBL] [Abstract][Full Text] [Related]
10. Differential activation of pregnane X receptor and constitutive androstane receptor by buprenorphine in primary human hepatocytes and HepG2 cells.
Li L; Hassan HE; Tolson AH; Ferguson SS; Eddington ND; Wang H
J Pharmacol Exp Ther; 2010 Dec; 335(3):562-71. PubMed ID: 20829393
[TBL] [Abstract][Full Text] [Related]
11. Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.
Ohbuchi M; Yoshinari K; Kaneko H; Matsumoto S; Inoue A; Kawamura A; Usui T; Yamazoe Y
Antimicrob Agents Chemother; 2013 Mar; 57(3):1332-8. PubMed ID: 23274663
[TBL] [Abstract][Full Text] [Related]
12. Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes.
Gährs M; Roos R; Andersson PL; Schrenk D
Toxicol Appl Pharmacol; 2013 Oct; 272(1):77-85. PubMed ID: 23770461
[TBL] [Abstract][Full Text] [Related]
13. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
14. Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene.
Krausova L; Stejskalova L; Wang H; Vrzal R; Dvorak Z; Mani S; Pavek P
Biochem Pharmacol; 2011 Dec; 82(11):1771-80. PubMed ID: 21920351
[TBL] [Abstract][Full Text] [Related]
15. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
[TBL] [Abstract][Full Text] [Related]
16. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
Li L; Stanton JD; Tolson AH; Luo Y; Wang H
Pharm Res; 2009 Apr; 26(4):872-82. PubMed ID: 19034627
[TBL] [Abstract][Full Text] [Related]
17. Selective phthalate activation of naturally occurring human constitutive androstane receptor splice variants and the pregnane X receptor.
DeKeyser JG; Laurenzana EM; Peterson EC; Chen T; Omiecinski CJ
Toxicol Sci; 2011 Apr; 120(2):381-91. PubMed ID: 21227907
[TBL] [Abstract][Full Text] [Related]
18. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
[TBL] [Abstract][Full Text] [Related]
19. Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.
Tamasi V; Juvan P; Beer M; Rozman D; Meyer UA
Mol Pharm; 2009; 6(5):1573-81. PubMed ID: 19708687
[TBL] [Abstract][Full Text] [Related]
20. Interactions of sesquiterpenes zederone and germacrone with the human cytochrome P450 system.
Pimkaew P; Küblbeck J; Petsalo A; Jukka J; Suksamrarn A; Juvonen R; Auriola S; Piyachaturawat P; Honkakoski P
Toxicol In Vitro; 2013 Sep; 27(6):2005-12. PubMed ID: 23850985
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
