BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 24225203)

  • 1. Mitochondrial targeting of α-tocopheryl succinate enhances its anti-mesothelioma efficacy.
    Kovarova J; Bajzikova M; Vondrusova M; Stursa J; Goodwin J; Nguyen M; Zobalova R; Pesdar EA; Truksa J; Tomasetti M; Dong LF; Neuzil J
    Redox Rep; 2014 Jan; 19(1):16-25. PubMed ID: 24225203
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II.
    Dong LF; Jameson VJ; Tilly D; Cerny J; Mahdavian E; Marín-Hernández A; Hernández-Esquivel L; Rodríguez-Enríquez S; Stursa J; Witting PK; Stantic B; Rohlena J; Truksa J; Kluckova K; Dyason JC; Ledvina M; Salvatore BA; Moreno-Sánchez R; Coster MJ; Ralph SJ; Smith RA; Neuzil J
    J Biol Chem; 2011 Feb; 286(5):3717-28. PubMed ID: 21059645
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing.
    Rohlena J; Dong LF; Kluckova K; Zobalova R; Goodwin J; Tilly D; Stursa J; Pecinova A; Philimonenko A; Hozak P; Banerjee J; Ledvina M; Sen CK; Houstek J; Coster MJ; Neuzil J
    Antioxid Redox Signal; 2011 Dec; 15(12):2923-35. PubMed ID: 21902599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis.
    Truksa J; Dong LF; Rohlena J; Stursa J; Vondrusova M; Goodwin J; Nguyen M; Kluckova K; Rychtarcikova Z; Lettlova S; Spacilova J; Stapelberg M; Zoratti M; Neuzil J
    Antioxid Redox Signal; 2015 Apr; 22(11):883-900. PubMed ID: 25578105
    [TBL] [Abstract][Full Text] [Related]  

  • 5. (+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo.
    dos Santos GA; Abreu e Lima RS; Pestana CR; Lima AS; Scheucher PS; Thomé CH; Gimenes-Teixeira HL; Santana-Lemos BA; Lucena-Araujo AR; Rodrigues FP; Nasr R; Uyemura SA; Falcão RP; de Thé H; Pandolfi PP; Curti C; Rego EM
    Leukemia; 2012 Mar; 26(3):451-60. PubMed ID: 21869839
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular mechanism for the selective impairment of cancer mitochondrial function by a mitochondrially targeted vitamin E analogue.
    Rodríguez-Enríquez S; Hernández-Esquivel L; Marín-Hernández A; Dong LF; Akporiaye ET; Neuzil J; Ralph SJ; Moreno-Sánchez R
    Biochim Biophys Acta; 2012 Sep; 1817(9):1597-607. PubMed ID: 22627082
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II.
    Dong LF; Freeman R; Liu J; Zobalova R; Marin-Hernandez A; Stantic M; Rohlena J; Valis K; Rodriguez-Enriquez S; Butcher B; Goodwin J; Brunk UT; Witting PK; Moreno-Sanchez R; Scheffler IE; Ralph SJ; Neuzil J
    Clin Cancer Res; 2009 Mar; 15(5):1593-600. PubMed ID: 19223492
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tocopheramine succinate and tocopheryl succinate: mechanism of mitochondrial inhibition and superoxide radical production.
    Gruber J; Staniek K; Krewenka C; Moldzio R; Patel A; Böhmdorfer S; Rosenau T; Gille L
    Bioorg Med Chem; 2014 Jan; 22(2):684-91. PubMed ID: 24393721
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner.
    Yan B; Stantic M; Zobalova R; Bezawork-Geleta A; Stapelberg M; Stursa J; Prokopova K; Dong L; Neuzil J
    BMC Cancer; 2015 May; 15():401. PubMed ID: 25967547
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy.
    Dong LF; Jameson VJ; Tilly D; Prochazka L; Rohlena J; Valis K; Truksa J; Zobalova R; Mahdavian E; Kluckova K; Stantic M; Stursa J; Freeman R; Witting PK; Norberg E; Goodwin J; Salvatore BA; Novotna J; Turanek J; Ledvina M; Hozak P; Zhivotovsky B; Coster MJ; Ralph SJ; Smith RA; Neuzil J
    Free Radic Biol Med; 2011 Jun; 50(11):1546-55. PubMed ID: 21402148
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondrial targeting overcomes ABCA1-dependent resistance of lung carcinoma to α-tocopheryl succinate.
    Prochazka L; Koudelka S; Dong LF; Stursa J; Goodwin J; Neca J; Slavik J; Ciganek M; Masek J; Kluckova K; Nguyen M; Turanek J; Neuzil J
    Apoptosis; 2013 Mar; 18(3):286-99. PubMed ID: 23299931
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alpha-tocopheryl succinate inhibits malignant mesothelioma by disrupting the fibroblast growth factor autocrine loop: mechanism and the role of oxidative stress.
    Stapelberg M; Gellert N; Swettenham E; Tomasetti M; Witting PK; Procopio A; Neuzil J
    J Biol Chem; 2005 Jul; 280(27):25369-76. PubMed ID: 15878867
    [TBL] [Abstract][Full Text] [Related]  

  • 13. VCPA, a novel synthetic derivative of α-tocopheryl succinate, sensitizes human gastric cancer to doxorubicin-induced apoptosis via ROS-dependent mitochondrial dysfunction.
    Wu H; Liu S; Gong J; Liu J; Zhang Q; Leng X; Zhang N; Li Y
    Cancer Lett; 2017 May; 393():22-32. PubMed ID: 28216375
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alpha-Tocopheryl succinate: toxicity and lack of anti-tumour activity in immuno-competent mice.
    Ireland DJ; Kissick HT; Beilharz MW
    Food Chem Toxicol; 2008 Feb; 46(2):508-12. PubMed ID: 17923224
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Indoleamine-2,3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans.
    Stapelberg M; Zobalova R; Nguyen MN; Walker T; Stantic M; Goodwin J; Pasdar EA; Thai T; Prokopova K; Yan B; Hall S; de Pennington N; Thomas SR; Grant G; Stursa J; Bajzikova M; Meedeniya AC; Truksa J; Ralph SJ; Ansorge O; Dong LF; Neuzil J
    Free Radic Biol Med; 2014 Feb; 67():41-50. PubMed ID: 24145120
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Co-delivery nanocarriers targeting folate receptor and encapsulating 2-deoxyglucose and α-tocopheryl succinate enhance anti-tumor effect in vivo.
    Lei X; Li K; Liu Y; Wang ZY; Ruan BJ; Wang L; Xiang A; Wu D; Lu Z
    Int J Nanomedicine; 2017; 12():5701-5715. PubMed ID: 28848348
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of Mitochondrial Cell Death and Reversal of Anticancer Drug Resistance via Nanocarriers Composed of a Triphenylphosphonium Derivative of Tocopheryl Polyethylene Glycol Succinate.
    Singh Y; Viswanadham KKDR; Pawar VK; Meher J; Jajoriya AK; Omer A; Jaiswal S; Dewangan J; Bora HK; Singh P; Rath SK; Lal J; Mishra DP; Chourasia MK
    Mol Pharm; 2019 Sep; 16(9):3744-3759. PubMed ID: 31441308
    [TBL] [Abstract][Full Text] [Related]  

  • 18. α-Tocopheryloxyacetic acid is superior to α-tocopheryl succinate in suppressing HER2-high breast carcinomas due to its higher stability.
    Dong LF; Grant G; Massa H; Zobalova R; Akporiaye E; Neuzil J
    Int J Cancer; 2012 Sep; 131(5):1052-8. PubMed ID: 22038845
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tocopherol-associated protein-1 accelerates apoptosis induced by alpha-tocopheryl succinate in mesothelioma cells.
    Neuzil J; Dong LF; Wang XF; Zingg JM
    Biochem Biophys Res Commun; 2006 May; 343(4):1113-7. PubMed ID: 16579965
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alpha-tocopheryl succinate inhibits autophagic survival of prostate cancer cells induced by vitamin K3 and ascorbate to trigger cell death.
    Tomasetti M; Nocchi L; Neuzil J; Goodwin J; Nguyen M; Dong L; Manzella N; Staffolani S; Milanese C; Garrone B; Alleva R; Borghi B; Santarelli L; Guerrieri R
    PLoS One; 2012; 7(12):e52263. PubMed ID: 23272231
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.