277 related articles for article (PubMed ID: 24225533)
1. Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis.
Annunziata I; Patterson A; Helton D; Hu H; Moshiach S; Gomero E; Nixon R; d'Azzo A
Nat Commun; 2013; 4():2734. PubMed ID: 24225533
[TBL] [Abstract][Full Text] [Related]
2. Therapeutic Potential of Neu1 in Alzheimer's Disease Via the Immune System.
Khan A; Das S; Sergi C
Am J Alzheimers Dis Other Demen; 2021; 36():1533317521996147. PubMed ID: 33719595
[TBL] [Abstract][Full Text] [Related]
3. Neuraminidase 1 is a negative regulator of lysosomal exocytosis.
Yogalingam G; Bonten EJ; van de Vlekkert D; Hu H; Moshiach S; Connell SA; d'Azzo A
Dev Cell; 2008 Jul; 15(1):74-86. PubMed ID: 18606142
[TBL] [Abstract][Full Text] [Related]
4. Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease.
Lefort R; Pozueta J; Shelanski M
J Neurosci; 2012 Aug; 32(31):10674-85. PubMed ID: 22855816
[TBL] [Abstract][Full Text] [Related]
5. Lysosomal sialidase NEU1, its intracellular properties, deficiency, and use as a therapeutic agent.
Itoh K; Tsukimoto J
Glycoconj J; 2023 Dec; 40(6):611-619. PubMed ID: 38147151
[TBL] [Abstract][Full Text] [Related]
6. TFEB-mediated Enhancement of the Autophagy-lysosomal Pathway Dually Modulates the Process of Amyloid β-Protein Generation in Neurons.
Yamamoto F; Taniguchi K; Mamada N; Tamaoka A; Kametani F; Lakshmana MK; Araki W
Neuroscience; 2019 Mar; 402():11-22. PubMed ID: 30677488
[TBL] [Abstract][Full Text] [Related]
7. Intermittent enzyme replacement therapy with recombinant human β-galactosidase prevents neuraminidase 1 deficiency.
Luu AR; Wong C; Agrawal V; Wise N; Handyside B; Lo MJ; Pacheco G; Felix JB; Giaramita A; d'Azzo A; Vincelette J; Bullens S; Bunting S; Christianson TM; Hague CM; LeBowitz JH; Yogalingam G
J Biol Chem; 2020 Sep; 295(39):13556-13569. PubMed ID: 32727849
[TBL] [Abstract][Full Text] [Related]
8. Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation.
Caglayan S; Takagi-Niidome S; Liao F; Carlo AS; Schmidt V; Burgert T; Kitago Y; Füchtbauer EM; Füchtbauer A; Holtzman DM; Takagi J; Willnow TE
Sci Transl Med; 2014 Feb; 6(223):223ra20. PubMed ID: 24523320
[TBL] [Abstract][Full Text] [Related]
9. Involvement of receptor tyrosine kinase Tyro3 in amyloidogenic APP processing and β-amyloid deposition in Alzheimer's disease models.
Zheng Y; Wang Q; Xiao B; Lu Q; Wang Y; Wang X
PLoS One; 2012; 7(6):e39035. PubMed ID: 22701746
[TBL] [Abstract][Full Text] [Related]
10. Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia.
Bao J; Zheng L; Zhang Q; Li X; Zhang X; Li Z; Bai X; Zhang Z; Huo W; Zhao X; Shang S; Wang Q; Zhang C; Ji J
Protein Cell; 2016 Jun; 7(6):417-33. PubMed ID: 27209302
[TBL] [Abstract][Full Text] [Related]
11. Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.
Yang DS; Stavrides P; Mohan PS; Kaushik S; Kumar A; Ohno M; Schmidt SD; Wesson D; Bandyopadhyay U; Jiang Y; Pawlik M; Peterhoff CM; Yang AJ; Wilson DA; St George-Hyslop P; Westaway D; Mathews PM; Levy E; Cuervo AM; Nixon RA
Brain; 2011 Jan; 134(Pt 1):258-77. PubMed ID: 21186265
[TBL] [Abstract][Full Text] [Related]
12. Intracellular amyloid-β accumulation in calcium-binding protein-deficient neurons leads to amyloid-β plaque formation in animal model of Alzheimer's disease.
Moon M; Hong HS; Nam DW; Baik SH; Song H; Kook SY; Kim YS; Lee J; Mook-Jung I
J Alzheimers Dis; 2012; 29(3):615-28. PubMed ID: 22269161
[TBL] [Abstract][Full Text] [Related]
13. Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis.
van de Vlekkert D; Demmers J; Nguyen XX; Campos Y; Machado E; Annunziata I; Hu H; Gomero E; Qiu X; Bongiovanni A; Feghali-Bostwick CA; d'Azzo A
Sci Adv; 2019 Jul; 5(7):eaav3270. PubMed ID: 31328155
[TBL] [Abstract][Full Text] [Related]
14. Dynamic presenilin 1 and synaptotagmin 1 interaction modulates exocytosis and amyloid β production.
Zoltowska KM; Maesako M; Lushnikova I; Takeda S; Keller LJ; Skibo G; Hyman BT; Berezovska O
Mol Neurodegener; 2017 Feb; 12(1):15. PubMed ID: 28193235
[TBL] [Abstract][Full Text] [Related]
15. The Role of Lysosomes in a Broad Disease-Modifying Approach Evaluated across Transgenic Mouse Models of Alzheimer's Disease and Parkinson's Disease and Models of Mild Cognitive Impairment.
Hwang J; Estick CM; Ikonne US; Butler D; Pait MC; Elliott LH; Ruiz S; Smith K; Rentschler KM; Mundell C; Almeida MF; Stumbling Bear N; Locklear JP; Abumohsen Y; Ivey CM; Farizatto KLG; Bahr BA
Int J Mol Sci; 2019 Sep; 20(18):. PubMed ID: 31505809
[TBL] [Abstract][Full Text] [Related]
16. A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models.
Song JX; Malampati S; Zeng Y; Durairajan SSK; Yang CB; Tong BC; Iyaswamy A; Shang WB; Sreenivasmurthy SG; Zhu Z; Cheung KH; Lu JH; Tang C; Xu N; Li M
Aging Cell; 2020 Feb; 19(2):e13069. PubMed ID: 31858697
[TBL] [Abstract][Full Text] [Related]
17. Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus.
Torres M; Jimenez S; Sanchez-Varo R; Navarro V; Trujillo-Estrada L; Sanchez-Mejias E; Carmona I; Davila JC; Vizuete M; Gutierrez A; Vitorica J
Mol Neurodegener; 2012 Nov; 7():59. PubMed ID: 23173743
[TBL] [Abstract][Full Text] [Related]
18. Alzheimer's disease.
De-Paula VJ; Radanovic M; Diniz BS; Forlenza OV
Subcell Biochem; 2012; 65():329-52. PubMed ID: 23225010
[TBL] [Abstract][Full Text] [Related]
19. Amyloid β peptide promotes lysosomal degradation of clusterin via sortilin in hippocampal primary neurons.
Wang Y; Qin X; Paudel HK
Neurobiol Dis; 2017 Jul; 103():78-88. PubMed ID: 28396259
[TBL] [Abstract][Full Text] [Related]
20. Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-β levels in brain.
Henderson BW; Gentry EG; Rush T; Troncoso JC; Thambisetty M; Montine TJ; Herskowitz JH
J Neurochem; 2016 Aug; 138(4):525-31. PubMed ID: 27246255
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]