BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 24252946)

  • 1. Metformin represses drug-induced expression of CYP2B6 by modulating the constitutive androstane receptor signaling.
    Yang H; Garzel B; Heyward S; Moeller T; Shapiro P; Wang H
    Mol Pharmacol; 2014 Feb; 85(2):249-60. PubMed ID: 24252946
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3).
    Laurenzana EM; Chen T; Kannuswamy M; Sell BE; Strom SC; Li Y; Omiecinski CJ
    Mol Pharmacol; 2012 Nov; 82(5):918-28. PubMed ID: 22896671
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.
    Maglich JM; Parks DJ; Moore LB; Collins JL; Goodwin B; Billin AN; Stoltz CA; Kliewer SA; Lambert MH; Willson TM; Moore JT
    J Biol Chem; 2003 May; 278(19):17277-83. PubMed ID: 12611900
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation.
    Pascussi JM; Gerbal-Chaloin S; Fabre JM; Maurel P; Vilarem MJ
    Mol Pharmacol; 2000 Dec; 58(6):1441-50. PubMed ID: 11093784
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
    Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
    J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p38 Mitogen-activated protein kinase regulates nuclear receptor CAR that activates the CYP2B6 gene.
    Saito K; Moore R; Negishi M
    Drug Metab Dispos; 2013 Jun; 41(6):1170-3. PubMed ID: 23539296
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene.
    Krausova L; Stejskalova L; Wang H; Vrzal R; Dvorak Z; Mani S; Pavek P
    Biochem Pharmacol; 2011 Dec; 82(11):1771-80. PubMed ID: 21920351
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
    Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
    J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
    [TBL] [Abstract][Full Text] [Related]  

  • 9. AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line.
    Rencurel F; Stenhouse A; Hawley SA; Friedberg T; Hardie DG; Sutherland C; Wolf CR
    J Biol Chem; 2005 Feb; 280(6):4367-73. PubMed ID: 15572372
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ATF5 is a highly abundant liver-enriched transcription factor that cooperates with constitutive androstane receptor in the transactivation of CYP2B6: implications in hepatic stress responses.
    Pascual M; Gómez-Lechón MJ; Castell JV; Jover R
    Drug Metab Dispos; 2008 Jun; 36(6):1063-72. PubMed ID: 18332083
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3).
    Auerbach SS; Stoner MA; Su S; Omiecinski CJ
    Mol Pharmacol; 2005 Nov; 68(5):1239-53. PubMed ID: 16099843
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3).
    Breuker C; Moreau A; Lakhal L; Tamasi V; Parmentier Y; Meyer U; Maurel P; Lumbroso S; Vilarem MJ; Pascussi JM
    Endocrinology; 2010 Apr; 151(4):1653-61. PubMed ID: 20185760
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of gender-dependent CYP2A expression in pigs: involvement of androgens and CAR.
    Gillberg M; Skaanild MT; Friis C
    Basic Clin Pharmacol Toxicol; 2006 May; 98(5):480-7. PubMed ID: 16635107
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of the Constitutive Androstane Receptor Increases the Therapeutic Index of CHOP in Lymphoma Treatment.
    Hedrich WD; Xiao J; Heyward S; Zhang Y; Zhang J; Baer MR; Hassan HE; Wang H
    Mol Cancer Ther; 2016 Mar; 15(3):392-401. PubMed ID: 26823489
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of CYP2B6 and CYP3A4 expression by 1-aminobenzotriazole (ABT) in human hepatocytes.
    Yang K; Koh KH; Jeong H
    Drug Metab Lett; 2010 Aug; 4(3):129-33. PubMed ID: 20642445
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes.
    Koike C; Moore R; Negishi M
    Mol Pharmacol; 2007 May; 71(5):1217-21. PubMed ID: 17314319
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin.
    Wang H; Faucette S; Moore R; Sueyoshi T; Negishi M; LeCluyse E
    J Biol Chem; 2004 Jul; 279(28):29295-301. PubMed ID: 15123723
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor.
    Li L; Chen T; Stanton JD; Sueyoshi T; Negishi M; Wang H
    Mol Pharmacol; 2008 Aug; 74(2):443-53. PubMed ID: 18492798
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.