BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 24256368)

  • 1. Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence.
    Di Leva FS; Zizza P; Cingolani C; D'Angelo C; Pagano B; Amato J; Salvati E; Sissi C; Pinato O; Marinelli L; Cavalli A; Cosconati S; Novellino E; Randazzo A; Biroccio A
    J Med Chem; 2013 Dec; 56(23):9646-54. PubMed ID: 24256368
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
    Musumeci D; Amato J; Zizza P; Platella C; Cosconati S; Cingolani C; Biroccio A; Novellino E; Randazzo A; Giancola C; Pagano B; Montesarchio D
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1341-1352. PubMed ID: 28130159
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of novel 4,5-bis(dialkylaminoalkyl)-substituted acridines as potent telomeric G-quadruplex ligands.
    Laronze-Cochard M; Kim YM; Brassart B; Riou JF; Laronze JY; Sapi J
    Eur J Med Chem; 2009 Oct; 44(10):3880-8. PubMed ID: 19467742
    [TBL] [Abstract][Full Text] [Related]  

  • 4. C-11 diamino cryptolepine derivatives NSC748392, NSC748393, and NSC748394: anticancer profile and G-quadruplex stabilization.
    Lavrado J; Reszka AP; Moreira R; Neidle S; Paulo A
    Bioorg Med Chem Lett; 2010 Dec; 20(23):7042-5. PubMed ID: 20952194
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands.
    Collie GW; Promontorio R; Hampel SM; Micco M; Neidle S; Parkinson GN
    J Am Chem Soc; 2012 Feb; 134(5):2723-31. PubMed ID: 22280460
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death.
    Cosconati S; Rizzo A; Trotta R; Pagano B; Iachettini S; De Tito S; Lauri I; Fotticchia I; Giustiniano M; Marinelli L; Giancola C; Novellino E; Biroccio A; Randazzo A
    J Med Chem; 2012 Nov; 55(22):9785-92. PubMed ID: 23057850
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Platinum(II) phenanthroimidazoles for targeting telomeric G-quadruplexes.
    Castor KJ; Mancini J; Fakhoury J; Weill N; Kieltyka R; Englebienne P; Avakyan N; Mittermaier A; Autexier C; Moitessier N; Sleiman HF
    ChemMedChem; 2012 Jan; 7(1):85-94. PubMed ID: 22052801
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Looking for efficient G-quadruplex ligands: evidence for selective stabilizing properties and telomere damage by drug-like molecules.
    Pagano B; Amato J; Iaccarino N; Cingolani C; Zizza P; Biroccio A; Novellino E; Randazzo A
    ChemMedChem; 2015 Apr; 10(4):640-9. PubMed ID: 25694275
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis of 4,5-diazafluorene derivatives and their anticancer activity via targeting telomeric DNA G-quadruplex.
    Zhou K; Liu J; Xiong X; Cheng M; Hu X; Narva S; Zhao X; Wu Y; Zhang W
    Eur J Med Chem; 2019 Sep; 178():484-499. PubMed ID: 31202994
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of G-quadruplexes with nonintercalating duplex-DNA minor groove binding ligands.
    Jain AK; Bhattacharya S
    Bioconjug Chem; 2011 Dec; 22(12):2355-68. PubMed ID: 22074555
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization.
    Rocca R; Moraca F; Costa G; Nadai M; Scalabrin M; Talarico C; Distinto S; Maccioni E; Ortuso F; Artese A; Alcaro S; Richter SN
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1329-1340. PubMed ID: 28025082
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes.
    Sparapani S; Haider SM; Doria F; Gunaratnam M; Neidle S
    J Am Chem Soc; 2010 Sep; 132(35):12263-72. PubMed ID: 20718414
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Homogeneous selecting of a quadruplex-binding ligand-based gold nanoparticle fluorescence resonance energy transfer assay.
    Jin Y; Li H; Bai J
    Anal Chem; 2009 Jul; 81(14):5709-15. PubMed ID: 19527045
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.
    Moore MJ; Schultes CM; Cuesta J; Cuenca F; Gunaratnam M; Tanious FA; Wilson WD; Neidle S
    J Med Chem; 2006 Jan; 49(2):582-99. PubMed ID: 16420044
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of selective ligands for telomeric RNA G-quadruplexes (TERRA) through 19F-NMR based fragment screening.
    Garavís M; López-Méndez B; Somoza A; Oyarzabal J; Dalvit C; Villasante A; Campos-Olivas R; González C
    ACS Chem Biol; 2014 Jul; 9(7):1559-66. PubMed ID: 24837572
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting of Telomeric Repeat-Containing RNA G-Quadruplexes: From Screening to Biophysical and Biological Characterization of a New Hit Compound.
    Marzano S; Pagano B; Iaccarino N; Di Porzio A; De Tito S; Vertecchi E; Salvati E; Randazzo A; Amato J
    Int J Mol Sci; 2021 Sep; 22(19):. PubMed ID: 34638655
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Linking of Antitumor trans NHC-Pt(II) Complexes to G-Quadruplex DNA Ligand for Telomeric Targeting.
    Betzer JF; Nuter F; Chtchigrovsky M; Hamon F; Kellermann G; Ali S; Calméjane MA; Roque S; Poupon J; Cresteil T; Teulade-Fichou MP; Marinetti A; Bombard S
    Bioconjug Chem; 2016 Jun; 27(6):1456-70. PubMed ID: 27115175
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?
    Amato J; Pagano A; Cosconati S; Amendola G; Fotticchia I; Iaccarino N; Marinello J; De Magis A; Capranico G; Novellino E; Pagano B; Randazzo A
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1271-1280. PubMed ID: 27836755
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hybrid ligand-alkylating agents targeting telomeric G-quadruplex structures.
    Doria F; Nadai M; Folini M; Di Antonio M; Germani L; Percivalle C; Sissi C; Zaffaroni N; Alcaro S; Artese A; Richter SN; Freccero M
    Org Biomol Chem; 2012 Apr; 10(14):2798-806. PubMed ID: 22367401
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Recent advances in targeting the telomeric G-quadruplex DNA sequence with small molecules as a strategy for anticancer therapies.
    Islam MK; Jackson PJ; Rahman KM; Thurston DE
    Future Med Chem; 2016 Jul; 8(11):1259-90. PubMed ID: 27442231
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.