101 related articles for article (PubMed ID: 2425957)
1. Incorporation of 5-fluorodeoxycytidine and metabolites into nucleic acids of human MCF-7 breast carcinoma cells.
Kaysen J; Spriggs D; Kufe D
Cancer Res; 1986 Sep; 46(9):4534-8. PubMed ID: 2425957
[TBL] [Abstract][Full Text] [Related]
2. Tumor-selective metabolism of 5-fluoro-2'-deoxycytidine coadministered with tetrahydrouridine compared to 5-fluorouracil in mice bearing Lewis lung carcinoma.
Boothman DA; Briggle TV; Greer S
Cancer Res; 1987 May; 47(9):2354-62. PubMed ID: 2952263
[TBL] [Abstract][Full Text] [Related]
3. Protective, tumor-selective dual pathway activation of 5-fluoro-2'-deoxycytidine provided by tetrahydrouridine in mice bearing mammary adenocarcinoma-755.
Boothman DA; Briggle TV; Greer S
Cancer Res; 1987 May; 47(9):2344-53. PubMed ID: 2436761
[TBL] [Abstract][Full Text] [Related]
4. Use of 5-fluorodeoxycytidine and tetrahydrouridine to exploit high levels of deoxycytidylate deaminase in tumors to achieve DNA- and target-directed therapies.
Mekras JA; Boothman DA; Perez LM; Greer S
Cancer Res; 1984 Jun; 44(6):2551-60. PubMed ID: 6539164
[TBL] [Abstract][Full Text] [Related]
5. Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU).
Beumer JH; Parise RA; Newman EM; Doroshow JH; Synold TW; Lenz HJ; Egorin MJ
Cancer Chemother Pharmacol; 2008 Jul; 62(2):363-8. PubMed ID: 17899082
[TBL] [Abstract][Full Text] [Related]
6. 5-Fluorouracil incorporation in DNA of human breast carcinoma cells.
Major PP; Egan E; Herrick D; Kufe DW
Cancer Res; 1982 Aug; 42(8):3005-9. PubMed ID: 6212116
[TBL] [Abstract][Full Text] [Related]
7. Effect of methotrexate on incorporation and excision of 5-fluorouracil residues in human breast carcinoma DNA.
Herrick DJ; Major PP; Kufe DW
Cancer Res; 1982 Dec; 42(12):5015-7. PubMed ID: 7139606
[TBL] [Abstract][Full Text] [Related]
8. The role of fluorinated pyrimidine analogues in the induction of the in vitro expression of the fragile X chromosome.
Vandamme B; Liebaers I; Hens L; Bernheim JL; Roobol C
Hum Genet; 1988 Aug; 79(4):341-6. PubMed ID: 2970425
[TBL] [Abstract][Full Text] [Related]
9. Use of 5-trifluoromethyldeoxycytidine and tetrahydrouridine to circumvent catabolism and exploit high levels of cytidine deaminase in tumors to achieve DNA- and target-directed therapies.
Mekras JA; Boothman DA; Greer SB
Cancer Res; 1985 Nov; 45(11 Pt 1):5270-80. PubMed ID: 2932216
[TBL] [Abstract][Full Text] [Related]
10. Metabolism and mechanism of action of 5-fluorodeoxycytidine.
Newman EM; Santi DV
Proc Natl Acad Sci U S A; 1982 Nov; 79(21):6419-23. PubMed ID: 6959127
[TBL] [Abstract][Full Text] [Related]
11. Pharmacokinetics, metabolism, and oral bioavailability of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine in mice.
Beumer JH; Eiseman JL; Parise RA; Joseph E; Holleran JL; Covey JM; Egorin MJ
Clin Cancer Res; 2006 Dec; 12(24):7483-91. PubMed ID: 17138702
[TBL] [Abstract][Full Text] [Related]
12. Evaluation of 5-[
Yu HM; Chiu CH; Chen WT; Wu CH; Lin PY; Huang YY; Chen JH; Tzen KY; Shiue CY; Lin WJ
Appl Radiat Isot; 2019 Jun; 148():152-159. PubMed ID: 30959352
[TBL] [Abstract][Full Text] [Related]
13. Oral and intravenous pharmacokinetics of 5-fluoro-2'-deoxycytidine and THU in cynomolgus monkeys and humans.
Holleran JL; Beumer JH; McCormick DL; Johnson WD; Newman EM; Doroshow JH; Kummar S; Covey JM; Davis M; Eiseman JL
Cancer Chemother Pharmacol; 2015 Oct; 76(4):803-11. PubMed ID: 26321472
[TBL] [Abstract][Full Text] [Related]
14. Effect of 5-fluorouracil on RNA metabolism in Novikoff hepatoma cells.
Cory JG; Breland JC; Carter GL
Cancer Res; 1979 Dec; 39(12):4905-13. PubMed ID: 498116
[TBL] [Abstract][Full Text] [Related]
15. LC-MS/MS assay for the quantitation of FdCyd and its metabolites FdUrd and FU in human plasma.
Holleran JL; Eiseman JL; Parise RA; Kummar S; Beumer JH
J Pharm Biomed Anal; 2016 Sep; 129():359-366. PubMed ID: 27454087
[TBL] [Abstract][Full Text] [Related]
16. Therapeutic efficacy of fluoropyrimidines depends on the duration of thymidylate synthase inhibition in the murine colon 26-B carcinoma tumor model.
van Laar JA; van der Wilt CL; Rustum YM; Noordhuis P; Smid K; Pinedo HM; Peters GJ
Clin Cancer Res; 1996 Aug; 2(8):1327-33. PubMed ID: 9816304
[TBL] [Abstract][Full Text] [Related]
17. Reversal of deamination-related cytotoxicity of 5-methyl-2'-deoxycytidine by tetrahydrouridine in human leukemia cells.
Jekunen A; Vilpo JA
J Natl Cancer Inst; 1984 Nov; 73(5):1087-91. PubMed ID: 6593484
[TBL] [Abstract][Full Text] [Related]
18. Effect of L-histidinol on the metabolism of 5-fluorouracil in the BALB/c x DBA/8 F1 murine tumor system.
Sawyer RC; Stolfi RL; Martin DS
Cancer Res; 1988 Dec; 48(23):6664-8. PubMed ID: 2460227
[TBL] [Abstract][Full Text] [Related]
19. Stability of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in combination.
Guo D; Myrdal PB; Karlage KL; O'Connell SP; Wissinger TJ; Tabibi SE; Yalkowsky SH
AAPS PharmSciTech; 2010 Mar; 11(1):247-52. PubMed ID: 20151336
[TBL] [Abstract][Full Text] [Related]
20. Fluorodeoxyuridine-mediated modulation of iododeoxyuridine incorporation and radiosensitization in human colon cancer cells in vitro and in vivo.
Lawrence TS; Davis MA; McKeever PE; Maybaum J; Stetson PL; Normolle DP; Ensminger WD
Cancer Res; 1991 Aug; 51(15):3900-5. PubMed ID: 1830239
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]