BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 24266532)

  • 1. Mutation of nonessential cysteines shows that the NF-κB essential modulator forms a constitutive noncovalent dimer that binds IκB kinase-β with high affinity.
    Cote SM; Gilmore TD; Shaffer R; Weber U; Bollam R; Golden MS; Glover K; Herscovitch M; Ennis T; Allen KN; Whitty A
    Biochemistry; 2013 Dec; 52(51):9141-54. PubMed ID: 24266532
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO).
    Zhou L; Yeo AT; Ballarano C; Weber U; Allen KN; Gilmore TD; Whitty A
    Biochemistry; 2014 Dec; 53(50):7929-44. PubMed ID: 25400026
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.
    Solt LA; Madge LA; May MJ
    J Biol Chem; 2009 Oct; 284(40):27596-608. PubMed ID: 19666475
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347.
    Herscovitch M; Comb W; Ennis T; Coleman K; Yong S; Armstead B; Kalaitzidis D; Chandani S; Gilmore TD
    Biochem Biophys Res Commun; 2008 Feb; 367(1):103-8. PubMed ID: 18164680
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta.
    Solt LA; Madge LA; Orange JS; May MJ
    J Biol Chem; 2007 Mar; 282(12):8724-33. PubMed ID: 17244613
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity.
    Palkowitsch L; Leidner J; Ghosh S; Marienfeld RB
    J Biol Chem; 2008 Jan; 283(1):76-86. PubMed ID: 17977820
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Covalent modification of the NF-κB essential modulator (NEMO) by a chemical compound can regulate its ubiquitin binding properties in vitro.
    Hooper C; Jackson SS; Coughlin EE; Coon JJ; Miyamoto S
    J Biol Chem; 2014 Nov; 289(48):33161-74. PubMed ID: 25296760
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex.
    Fontan E; Traincard F; Levy SG; Yamaoka S; Véron M; Agou F
    FEBS J; 2007 May; 274(10):2540-51. PubMed ID: 17419723
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dimerization of the I kappa B kinase-binding domain of NEMO is required for tumor necrosis factor alpha-induced NF-kappa B activity.
    Marienfeld RB; Palkowitsch L; Ghosh S
    Mol Cell Biol; 2006 Dec; 26(24):9209-19. PubMed ID: 17000764
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NEMO oligomerization and its ubiquitin-binding properties.
    Ivins FJ; Montgomery MG; Smith SJ; Morris-Davies AC; Taylor IA; Rittinger K
    Biochem J; 2009 Jun; 421(2):243-51. PubMed ID: 19422324
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation.
    Zhang J; Clark K; Lawrence T; Peggie MW; Cohen P
    Biochem J; 2014 Aug; 461(3):531-7. PubMed ID: 24911653
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages.
    De Falco F; Di Giovanni C; Cerchia C; De Stefano D; Capuozzo A; Irace C; Iuvone T; Santamaria R; Carnuccio R; Lavecchia A
    Biochem Pharmacol; 2016 Mar; 104():83-94. PubMed ID: 26776306
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera's key metabolite withaferin A.
    Grover A; Shandilya A; Punetha A; Bisaria VS; Sundar D
    BMC Genomics; 2010 Dec; 11 Suppl 4(Suppl 4):S25. PubMed ID: 21143809
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome.
    Ngadjeua F; Chiaravalli J; Traincard F; Raynal B; Fontan E; Agou F
    J Biol Chem; 2013 Nov; 288(47):33722-33737. PubMed ID: 24100029
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding.
    Grubisha O; Kaminska M; Duquerroy S; Fontan E; Cordier F; Haouz A; Raynal B; Chiaravalli J; Delepierre M; Israël A; Véron M; Agou F
    J Mol Biol; 2010 Jan; 395(1):89-104. PubMed ID: 19854204
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].
    Wu CJ; Conze DB; Li T; Srinivasula SM; Ashwell JD
    Nat Cell Biol; 2006 Apr; 8(4):398-406. PubMed ID: 16547522
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structurally plastic NEMO and oligomerization prone IKK2 subunits define the behavior of human IKK2:NEMO complexes in solution.
    Ko MS; Biswas T; Mulero MC; Bobkov AA; Ghosh G; Huxford T
    Biochim Biophys Acta Proteins Proteom; 2020 Dec; 1868(12):140526. PubMed ID: 32853772
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-affinity interaction between IKKbeta and NEMO.
    Lo YC; Maddineni U; Chung JY; Rich RL; Myszka DG; Wu H
    Biochemistry; 2008 Mar; 47(10):3109-16. PubMed ID: 18266324
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NEMO ensures signaling specificity of the pleiotropic IKKβ by directing its kinase activity toward IκBα.
    Schröfelbauer B; Polley S; Behar M; Ghosh G; Hoffmann A
    Mol Cell; 2012 Jul; 47(1):111-21. PubMed ID: 22633953
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.
    Adli M; Merkhofer E; Cogswell P; Baldwin AS
    PLoS One; 2010 Feb; 5(2):e9428. PubMed ID: 20195534
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.