BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

371 related articles for article (PubMed ID: 24269967)

  • 1. Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage.
    Nakamura H; Etrych T; Chytil P; Ohkubo M; Fang J; Ulbrich K; Maeda H
    J Control Release; 2014 Jan; 174():81-7. PubMed ID: 24269967
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice.
    Nakamura H; Koziolová E; Etrych T; Chytil P; Fang J; Ulbrich K; Maeda H
    Eur J Pharm Biopharm; 2015 Feb; 90():90-6. PubMed ID: 25460144
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pronounced Cellular Uptake of Pirarubicin versus That of Other Anthracyclines: Comparison of HPMA Copolymer Conjugates of Pirarubicin and Doxorubicin.
    Nakamura H; Koziolová E; Chytil P; Tsukigawa K; Fang J; Haratake M; Ulbrich K; Etrych T; Maeda H
    Mol Pharm; 2016 Dec; 13(12):4106-4115. PubMed ID: 27934482
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intratumoral Distribution and pH-Dependent Drug Release of High Molecular Weight HPMA Copolymer Drug Conjugates Strongly Depend on Specific Tumor Substructure and Microenvironment.
    Noack AK; Lucas H; Chytil P; Etrych T; Mäder K; Mueller T
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32825790
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance.
    Braunová A; Kostka L; Sivák L; Cuchalová L; Hvězdová Z; Laga R; Filippov S; Černoch P; Pechar M; Janoušková O; Šírová M; Etrych T
    J Control Release; 2017 Jan; 245():41-51. PubMed ID: 27871991
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HPMA copolymer conjugate with pirarubicin: In vitro and ex vivo stability and drug release study.
    Islam W; Fang J; Etrych T; Chytil P; Ulbrich K; Sakoguchi A; Kusakabe K; Maeda H
    Int J Pharm; 2018 Jan; 536(1):108-115. PubMed ID: 29133205
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Superior Penetration and Cytotoxicity of HPMA Copolymer Conjugates of Pirarubicin in Tumor Cell Spheroid.
    Nakamura H; Koziolová E; Chytil P; Etrych T; Haratake M; Maeda H
    Mol Pharm; 2019 Aug; 16(8):3452-3459. PubMed ID: 31294568
    [No Abstract]   [Full Text] [Related]  

  • 8. Tumor targeting by pH-sensitive, biodegradable, cross-linked N-(2-hydroxypropyl) methacrylamide copolymer micelles.
    Zhou Z; Li L; Yang Y; Xu X; Huang Y
    Biomaterials; 2014 Aug; 35(24):6622-35. PubMed ID: 24814427
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and therapeutic effect of styrene-maleic acid copolymer-conjugated pirarubicin.
    Tsukigawa K; Liao L; Nakamura H; Fang J; Greish K; Otagiri M; Maeda H
    Cancer Sci; 2015 Mar; 106(3):270-8. PubMed ID: 25529761
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of the pharmacological and biological properties of HPMA copolymer-pirarubicin conjugates: A single-chain copolymer conjugate and its biodegradable tandem-diblock copolymer conjugate.
    Etrych T; Tsukigawa K; Nakamura H; Chytil P; Fang J; Ulbrich K; Otagiri M; Maeda H
    Eur J Pharm Sci; 2017 Aug; 106():10-19. PubMed ID: 28528285
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Development of Tumor-targeting Antitumor Agents Based on Polymer Effect].
    Nakamura H
    Yakugaku Zasshi; 2020; 140(10):1243-1249. PubMed ID: 32999203
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel.
    Šírová M; Strohalm J; Chytil P; Lidický O; Tomala J; Říhová B; Etrych T
    J Control Release; 2017 Jan; 246():1-11. PubMed ID: 27940304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Missile-Type Tumor-Targeting Polymer Drug, P-THP, Seeks Tumors via Three Different Steps Based on the EPR Effect].
    Maeda H; Fang J; Ulbrich K; Etrych T; Nakamura H
    Gan To Kagaku Ryoho; 2016 May; 43(5):549-57. PubMed ID: 27210083
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Biodistribution of N-(2-hydroxypropyl) methacrylamide copolymer-bound mitoxantrone in mice bearing Ehrlich solid tumor].
    Huang Y; Zhang Z; Liu W
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi; 2004 Dec; 21(6):930-4. PubMed ID: 15646335
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours.
    Etrych T; Subr V; Laga R; Ríhová B; Ulbrich K
    Eur J Pharm Sci; 2014 Jul; 58():1-12. PubMed ID: 24632485
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Selective tumor-accumulation of HPMA copolymer-mitoxantrone conjugates].
    Huang Y; Zhang ZR
    Yao Xue Xue Bao; 2004 May; 39(5):374-9. PubMed ID: 15338883
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synergistic enhancement of anticancer therapeutic efficacy of HPMA copolymer doxorubicin conjugates via combination of ligand modification and stimuli-response srategies.
    Li L; Zhou M; Huang Y
    Int J Pharm; 2018 Jan; 536(1):450-458. PubMed ID: 29237570
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.
    Tomalova B; Sirova M; Rossmann P; Pola R; Strohalm J; Chytil P; Cerny V; Tomala J; Kabesova M; Rihova B; Ulbrich K; Etrych T; Kovar M
    J Control Release; 2016 Feb; 223():1-10. PubMed ID: 26708020
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The same drug but a different mechanism of action: comparison of free doxorubicin with two different N-(2-hydroxypropyl)methacrylamide copolymer-bound doxorubicin conjugates in EL-4 cancer cell line.
    Kovár L; Strohalm J; Chytil P; Mrkvan T; Kovár M; Hovorka O; Ulbrich K; Ríhová B
    Bioconjug Chem; 2007; 18(3):894-902. PubMed ID: 17402705
    [TBL] [Abstract][Full Text] [Related]  

  • 20. pH-Responsive Polymer Conjugate of Pirarubicin With Styrene Maleic Acid Copolymer as a Potential Therapeutic for Ovarian Cancer.
    Liu L; Sun J; Yin H; Fang J; Jin X
    J Pharm Sci; 2016 May; 105(5):1595-1602. PubMed ID: 27020984
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.