These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
284 related articles for article (PubMed ID: 24282292)
1. Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation. Crick SL; Ruff KM; Garai K; Frieden C; Pappu RV Proc Natl Acad Sci U S A; 2013 Dec; 110(50):20075-80. PubMed ID: 24282292 [TBL] [Abstract][Full Text] [Related]
2. Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin. Caron NS; Desmond CR; Xia J; Truant R Proc Natl Acad Sci U S A; 2013 Sep; 110(36):14610-5. PubMed ID: 23898200 [TBL] [Abstract][Full Text] [Related]
3. A coarse-grained model for polyglutamine aggregation modulated by amphipathic flanking sequences. Ruff KM; Khan SJ; Pappu RV Biophys J; 2014 Sep; 107(5):1226-1235. PubMed ID: 25185558 [TBL] [Abstract][Full Text] [Related]
4. Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers. Posey AE; Ruff KM; Harmon TS; Crick SL; Li A; Diamond MI; Pappu RV J Biol Chem; 2018 Mar; 293(10):3734-3746. PubMed ID: 29358329 [TBL] [Abstract][Full Text] [Related]
5. A series of N-terminal epitope tagged Hdh knock-in alleles expressing normal and mutant huntingtin: their application to understanding the effect of increasing the length of normal Huntingtin's polyglutamine stretch on CAG140 mouse model pathogenesis. Zheng S; Ghitani N; Blackburn JS; Liu JP; Zeitlin SO Mol Brain; 2012 Aug; 5():28. PubMed ID: 22892315 [TBL] [Abstract][Full Text] [Related]
6. Inhibition of huntingtin aggregation by its N-terminal 17-residue peptide and its analogs. Belwal VK; Vijayakumar A; Chaudhary N Arch Biochem Biophys; 2021 Nov; 712():109033. PubMed ID: 34534539 [TBL] [Abstract][Full Text] [Related]
7. Structure and Dynamics of the Huntingtin Exon-1 N-Terminus: A Solution NMR Perspective. Baias M; Smith PE; Shen K; Joachimiak LA; Żerko S; Koźmiński W; Frydman J; Frydman L J Am Chem Soc; 2017 Jan; 139(3):1168-1176. PubMed ID: 28085263 [TBL] [Abstract][Full Text] [Related]
8. Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein. Nucifora LG; Burke KA; Feng X; Arbez N; Zhu S; Miller J; Yang G; Ratovitski T; Delannoy M; Muchowski PJ; Finkbeiner S; Legleiter J; Ross CA; Poirier MA J Biol Chem; 2012 May; 287(19):16017-28. PubMed ID: 22433867 [TBL] [Abstract][Full Text] [Related]
9. F-actin binding regions on the androgen receptor and huntingtin increase aggregation and alter aggregate characteristics. Angeli S; Shao J; Diamond MI PLoS One; 2010 Feb; 5(2):e9053. PubMed ID: 20140226 [TBL] [Abstract][Full Text] [Related]
10. Chaperone protein HYPK interacts with the first 17 amino acid region of Huntingtin and modulates mutant HTT-mediated aggregation and cytotoxicity. Choudhury KR; Bhattacharyya NP Biochem Biophys Res Commun; 2015 Jan; 456(1):66-73. PubMed ID: 25446099 [TBL] [Abstract][Full Text] [Related]
11. The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms. Pandey NK; Isas JM; Rawat A; Lee RV; Langen J; Pandey P; Langen R J Biol Chem; 2018 Feb; 293(7):2597-2605. PubMed ID: 29282287 [TBL] [Abstract][Full Text] [Related]
13. Does N-terminal huntingtin function as a 'holdase' for inhibiting cellular protein aggregation? Sethi R; Tripathi N; Pallapati AR; Gaikar A; Bharatam PV; Roy I FEBS J; 2018 May; 285(10):1791-1811. PubMed ID: 29630769 [TBL] [Abstract][Full Text] [Related]
14. An N-terminal nuclear export signal regulates trafficking and aggregation of Huntingtin (Htt) protein exon 1. Zheng Z; Li A; Holmes BB; Marasa JC; Diamond MI J Biol Chem; 2013 Mar; 288(9):6063-71. PubMed ID: 23319588 [TBL] [Abstract][Full Text] [Related]