159 related articles for article (PubMed ID: 24286145)
1. Generation of a patient-derived chordoma xenograft and characterization of the phosphoproteome in a recurrent chordoma.
Davies JM; Robinson AE; Cowdrey C; Mummaneni PV; Ducker GS; Shokat KM; Bollen A; Hann B; Phillips JJ
J Neurosurg; 2014 Feb; 120(2):331-6. PubMed ID: 24286145
[TBL] [Abstract][Full Text] [Related]
2. Characterization of a Clival Chordoma Xenograft Model Reveals Tumor Genomic Instability.
Diaz RJ; Luck A; Bondoc A; Golbourn B; Picard D; Remke M; Loukides J; Sabha N; Smith C; Cusimano MD; Rutka JT
Am J Pathol; 2018 Dec; 188(12):2902-2911. PubMed ID: 30248342
[TBL] [Abstract][Full Text] [Related]
3. Molecular characterization of chordoma xenografts generated from a novel primary chordoma cell source and two chordoma cell lines.
Karikari IO; Gilchrist CL; Jing L; Alcorta DA; Chen J; Richardson WJ; Gabr MA; Bell RD; Kelley MJ; Bagley CA; Setton LA
J Neurosurg Spine; 2014 Sep; 21(3):386-93. PubMed ID: 24905390
[TBL] [Abstract][Full Text] [Related]
4. Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition.
Zhang H; Cohen AL; Krishnakumar S; Wapnir IL; Veeriah S; Deng G; Coram MA; Piskun CM; Longacre TA; Herrler M; Frimannsson DO; Telli ML; Dirbas FM; Matin AC; Dairkee SH; Larijani B; Glinsky GV; Bild AH; Jeffrey SS
Breast Cancer Res; 2014 Apr; 16(2):R36. PubMed ID: 24708766
[TBL] [Abstract][Full Text] [Related]
5. Combination of PI3K/mTOR inhibition demonstrates efficacy in human chordoma.
Schwab J; Antonescu C; Boland P; Healey J; Rosenberg A; Nielsen P; Iafrate J; Delaney T; Yoon S; Choy E; Harmon D; Raskin K; Yang C; Mankin H; Springfield D; Hornicek F; Duan Z
Anticancer Res; 2009 Jun; 29(6):1867-71. PubMed ID: 19528441
[TBL] [Abstract][Full Text] [Related]
6. Establishment and characterization of a primary human chordoma xenograft model.
Siu IM; Salmasi V; Orr BA; Zhao Q; Binder ZA; Tran C; Ishii M; Riggins GJ; Hann CL; Gallia GL
J Neurosurg; 2012 Apr; 116(4):801-9. PubMed ID: 22283186
[TBL] [Abstract][Full Text] [Related]
7. Chemotherapy of skull base chordoma tailored on responsiveness of patient-derived tumor cells to rapamycin.
Ricci-Vitiani L; Runci D; D'Alessandris QG; Cenci T; Martini M; Bianchi F; Maira G; Stancato L; De Maria R; Larocca LM; Pallini R
Neoplasia; 2013 Jul; 15(7):773-82. PubMed ID: 23814489
[TBL] [Abstract][Full Text] [Related]
8. Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.
Zhang S; Song X; Cao D; Xu Z; Fan B; Che L; Hu J; Chen B; Dong M; Pilo MG; Cigliano A; Evert K; Ribback S; Dombrowski F; Pascale RM; Cossu A; Vidili G; Porcu A; Simile MM; Pes GM; Giannelli G; Gordan J; Wei L; Evert M; Cong W; Calvisi DF; Chen X
J Hepatol; 2017 Dec; 67(6):1194-1203. PubMed ID: 28733220
[TBL] [Abstract][Full Text] [Related]
9. Assessing the efficacy of targeting the phosphatidylinositol 3-kinase/AKT/mTOR signaling pathway in endometrial cancer.
Bradford LS; Rauh-Hain A; Clark RM; Groeneweg JW; Zhang L; Borger D; Zukerberg LR; Growdon WB; Foster R; Rueda BR
Gynecol Oncol; 2014 May; 133(2):346-52. PubMed ID: 24561032
[TBL] [Abstract][Full Text] [Related]
10. Potential therapeutic targets for chordoma: PI3K/AKT/TSC1/TSC2/mTOR pathway.
Presneau N; Shalaby A; Idowu B; Gikas P; Cannon SR; Gout I; Diss T; Tirabosco R; Flanagan AM
Br J Cancer; 2009 May; 100(9):1406-14. PubMed ID: 19401700
[TBL] [Abstract][Full Text] [Related]
11. Mefloquine effectively targets gastric cancer cells through phosphatase-dependent inhibition of PI3K/Akt/mTOR signaling pathway.
Liu Y; Chen S; Xue R; Zhao J; Di M
Biochem Biophys Res Commun; 2016 Feb; 470(2):350-355. PubMed ID: 26780727
[TBL] [Abstract][Full Text] [Related]
12. A novel chordoma xenograft allows in vivo drug testing and reveals the importance of NF-κB signaling in chordoma biology.
Trucco MM; Awad O; Wilky BA; Goldstein SD; Huang R; Walker RL; Shah P; Katuri V; Gul N; Zhu YJ; McCarthy EF; Paz-Priel I; Meltzer PS; Austin CP; Xia M; Loeb DM
PLoS One; 2013; 8(11):e79950. PubMed ID: 24223206
[TBL] [Abstract][Full Text] [Related]
13. Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers.
Coussy F; El Botty R; Lavigne M; Gu C; Fuhrmann L; Briaux A; de Koning L; Dahmani A; Montaudon E; Morisset L; Huguet L; Sourd L; Painsec P; Chateau-Joubert S; Larcher T; Vacher S; Melaabi S; Salomon AV; Marangoni E; Bieche I
J Hematol Oncol; 2020 Feb; 13(1):13. PubMed ID: 32087759
[TBL] [Abstract][Full Text] [Related]
14. Synergistic anticancer efficacy of MEK inhibition and dual PI3K/mTOR inhibition in castration-resistant prostate cancer.
Park H; Kim Y; Sul JW; Jeong IG; Yi HJ; Ahn JB; Kang JS; Yun J; Hwang JJ; Kim CS
Prostate; 2015 Nov; 75(15):1747-59. PubMed ID: 26250606
[TBL] [Abstract][Full Text] [Related]
15. Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation.
Fang DD; Zhang CC; Gu Y; Jani JP; Cao J; Tsaparikos K; Yuan J; Thiel M; Jackson-Fisher A; Zong Q; Lappin PB; Hayashi T; Schwab RB; Wong A; John-Baptiste A; Bagrodia S; Los G; Bender S; Christensen J; Vanarsdale T
PLoS One; 2013; 8(6):e67258. PubMed ID: 23826249
[TBL] [Abstract][Full Text] [Related]
16. Erlotinib inhibits growth of a patient-derived chordoma xenograft.
Siu IM; Ruzevick J; Zhao Q; Connis N; Jiao Y; Bettegowda C; Xia X; Burger PC; Hann CL; Gallia GL
PLoS One; 2013; 8(11):e78895. PubMed ID: 24260133
[TBL] [Abstract][Full Text] [Related]
17. Y-box binding protein-1 promotes tumorigenesis and progression via the epidermal growth factor receptor/AKT pathway in spinal chordoma.
Liang C; Ma Y; Yong L; Yang C; Wang P; Liu X; Zhu B; Zhou H; Liu X; Liu Z
Cancer Sci; 2019 Jan; 110(1):166-179. PubMed ID: 30426615
[TBL] [Abstract][Full Text] [Related]
18. Targeting PI3K-AKT-mTOR by LY3023414 inhibits human skin squamous cell carcinoma cell growth in vitro and in vivo.
Zou Y; Ge M; Wang X
Biochem Biophys Res Commun; 2017 Aug; 490(2):385-392. PubMed ID: 28623128
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas.
Migliardi G; Sassi F; Torti D; Galimi F; Zanella ER; Buscarino M; Ribero D; Muratore A; Massucco P; Pisacane A; Risio M; Capussotti L; Marsoni S; Di Nicolantonio F; Bardelli A; Comoglio PM; Trusolino L; Bertotti A
Clin Cancer Res; 2012 May; 18(9):2515-25. PubMed ID: 22392911
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of Prostate Cancer DU-145 Cells Proliferation by
Li X; Tang Y; Yu F; Sun Y; Huang F; Chen Y; Yang Z; Ding G
Mar Drugs; 2018 Sep; 16(9):. PubMed ID: 30208576
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
