BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 24286211)

  • 1. Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1.
    Vilaça R; Silva E; Nadais A; Teixeira V; Matmati N; Gaifem J; Hannun YA; Sá Miranda MC; Costa V
    Mol Microbiol; 2014 Feb; 91(3):438-51. PubMed ID: 24286211
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in a yeast model of Niemann-Pick type C1.
    Vilaça R; Barros I; Matmati N; Silva E; Martins T; Teixeira V; Hannun YA; Costa V
    Biochim Biophys Acta Mol Basis Dis; 2018 Jan; 1864(1):79-88. PubMed ID: 28988886
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution.
    Malathi K; Higaki K; Tinkelenberg AH; Balderes DA; Almanzar-Paramio D; Wilcox LJ; Erdeniz N; Redican F; Padamsee M; Liu Y; Khan S; Alcantara F; Carstea ED; Morris JA; Sturley SL
    J Cell Biol; 2004 Feb; 164(4):547-56. PubMed ID: 14970192
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pkh1p-Ypk1p and Pkh1p-Sch9p Pathways Are Activated by Acetic Acid to Induce a Mitochondrial-Dependent Regulated Cell Death.
    Rego A; Mendes F; Costa V; Chaves SR; Côrte-Real M
    Oxid Med Cell Longev; 2020; 2020():7095078. PubMed ID: 32318242
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ncr1p, the yeast ortholog of mammalian Niemann Pick C1 protein, is dispensable for endocytic transport.
    Zhang S; Ren J; Li H; Zhang Q; Armstrong JS; Munn AL; Yang H
    Traffic; 2004 Dec; 5(12):1017-30. PubMed ID: 15522102
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sphingolipid/Pkh1/2-TORC1/Sch9 Signaling Regulates Ribosome Biogenesis in Tunicamycin-Induced Stress Response in Yeast.
    Yabuki Y; Ikeda A; Araki M; Kajiwara K; Mizuta K; Funato K
    Genetics; 2019 May; 212(1):175-186. PubMed ID: 30824472
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells.
    Barbosa AD; Osório H; Sims KJ; Almeida T; Alves M; Bielawski J; Amorim MA; Moradas-Ferreira P; Hannun YA; Costa V
    Mol Microbiol; 2011 Jul; 81(2):515-27. PubMed ID: 21707788
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A yeast model system for functional analysis of the Niemann-Pick type C protein 1 homolog, Ncr1p.
    Berger AC; Hanson PK; Wylie Nichols J; Corbett AH
    Traffic; 2005 Oct; 6(10):907-17. PubMed ID: 16138904
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Yeast lacking the amphiphysin family protein Rvs167 is sensitive to disruptions in sphingolipid levels.
    Toume M; Tani M
    FEBS J; 2016 Aug; 283(15):2911-28. PubMed ID: 27312128
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lipid Signaling via Pkh1/2 Regulates Fungal CO2 Sensing through the Kinase Sch9.
    Pohlers S; Martin R; Krüger T; Hellwig D; Hänel F; Kniemeyer O; Saluz HP; Van Dijck P; Ernst JF; Brakhage A; Mühlschlegel FA; Kurzai O
    mBio; 2017 Jan; 8(1):. PubMed ID: 28143980
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acetic acid induces Sch9p-dependent translocation of Isc1p from the endoplasmic reticulum into mitochondria.
    Rego A; Cooper KF; Snider J; Hannun YA; Costa V; Côrte-Real M; Chaves SR
    Biochim Biophys Acta Mol Cell Biol Lipids; 2018 Jun; 1863(6):576-583. PubMed ID: 29496584
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An "exacerbate-reverse" strategy in yeast identifies histone deacetylase inhibition as a correction for cholesterol and sphingolipid transport defects in human Niemann-Pick type C disease.
    Munkacsi AB; Chen FW; Brinkman MA; Higaki K; Gutiérrez GD; Chaudhari J; Layer JV; Tong A; Bard M; Boone C; Ioannou YA; Sturley SL
    J Biol Chem; 2011 Jul; 286(27):23842-51. PubMed ID: 21489983
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial reactive oxygen species-mediated cytotoxicity of intracellularly accumulated dihydrosphingosine in the yeast Saccharomyces cerevisiae.
    Arita N; Sakamoto R; Tani M
    FEBS J; 2020 Aug; 287(16):3427-3448. PubMed ID: 31944552
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.
    Newton J; Hait NC; Maceyka M; Colaco A; Maczis M; Wassif CA; Cougnoux A; Porter FD; Milstien S; Platt N; Platt FM; Spiegel S
    FASEB J; 2017 Apr; 31(4):1719-1730. PubMed ID: 28082351
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.
    Swinnen E; Wilms T; Idkowiak-Baldys J; Smets B; De Snijder P; Accardo S; Ghillebert R; Thevissen K; Cammue B; De Vos D; Bielawski J; Hannun YA; Winderickx J
    Mol Biol Cell; 2014 Jan; 25(1):196-211. PubMed ID: 24196832
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation in Saccharomyces cerevisiae.
    Swinnen E; Ghillebert R; Wilms T; Winderickx J
    FEMS Yeast Res; 2014 Feb; 14(1):17-32. PubMed ID: 24102693
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Iron Limitation Restores Autophagy and Increases Lifespan in the Yeast Model of Niemann-Pick Type C1.
    Martins TS; Costa RS; Vilaça R; Lemos C; Teixeira V; Pereira C; Costa V
    Int J Mol Sci; 2023 Mar; 24(7):. PubMed ID: 37047194
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sng1 associates with Nce102 to regulate the yeast Pkh-Ypk signalling module in response to sphingolipid status.
    García-Marqués S; Randez-Gil F; Dupont S; Garre E; Prieto JA
    Biochim Biophys Acta; 2016 Jun; 1863(6 Pt A):1319-33. PubMed ID: 27033517
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Down-regulating sphingolipid synthesis increases yeast lifespan.
    Huang X; Liu J; Dickson RC
    PLoS Genet; 2012 Feb; 8(2):e1002493. PubMed ID: 22319457
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density.
    Pan Y; Shadel GS
    Aging (Albany NY); 2009 Jan; 1(1):131-45. PubMed ID: 20157595
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.