BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 24307199)

  • 1. Regulation of death induction and chemosensitizing action of 3-bromopyruvate in myeloid leukemia cells: energy depletion, oxidative stress, and protein kinase activity modulation.
    Calviño E; Estañ MC; Sánchez-Martín C; Brea R; de Blas E; Boyano-Adánez Mdel C; Rial E; Aller P
    J Pharmacol Exp Ther; 2014 Feb; 348(2):324-35. PubMed ID: 24307199
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways.
    Estañ MC; Calviño E; de Blas E; Boyano-Adánez Mdel C; Mena ML; Gómez-Gómez M; Rial E; Aller P
    Biochem Pharmacol; 2012 Dec; 84(12):1604-16. PubMed ID: 23041229
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.
    Sánchez Y; Simón GP; Calviño E; de Blas E; Aller P
    J Pharmacol Exp Ther; 2010 Oct; 335(1):114-23. PubMed ID: 20605902
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
    Ou YC; Yang CR; Cheng CL; Raung SL; Hung YY; Chen CJ
    Eur J Pharmacol; 2007 Jun; 563(1-3):49-60. PubMed ID: 17341418
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation.
    Calviño E; Estañ MC; Simón GP; Sancho P; Boyano-Adánez Mdel C; de Blas E; Bréard J; Aller P
    Biochem Pharmacol; 2011 Dec; 82(11):1619-29. PubMed ID: 21889928
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
    Rahmani M; Reese E; Dai Y; Bauer C; Payne SG; Dent P; Spiegel S; Grant S
    Cancer Res; 2005 Mar; 65(6):2422-32. PubMed ID: 15781658
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Farnesyltransferase inhibitors interact synergistically with the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of SEK1/JNK.
    Dai Y; Rahmani M; Pei XY; Khanna P; Han SI; Mitchell C; Dent P; Grant S
    Blood; 2005 Feb; 105(4):1706-16. PubMed ID: 15494423
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of sorafenib on energy metabolism in breast cancer cells: role of AMPK-mTORC1 signaling.
    Fumarola C; Caffarra C; La Monica S; Galetti M; Alfieri RR; Cavazzoni A; Galvani E; Generali D; Petronini PG; Bonelli MA
    Breast Cancer Res Treat; 2013 Aug; 141(1):67-78. PubMed ID: 23963659
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib--the role of extracellular signal-regulated kinase counteraction.
    Manov I; Pollak Y; Broneshter R; Iancu TC
    FEBS J; 2011 Sep; 278(18):3494-507. PubMed ID: 21790999
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment.
    Filomeni G; Cardaci S; Da Costa Ferreira AM; Rotilio G; Ciriolo MR
    Biochem J; 2011 Aug; 437(3):443-53. PubMed ID: 21548882
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways.
    Amrán D; Sánchez Y; Fernández C; Ramos AM; de Blas E; Bréard J; Calle C; Aller P
    Biochim Biophys Acta; 2007 Nov; 1773(11):1653-63. PubMed ID: 17673311
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of AMPK signalling by doxorubicin: at the crossroads of the cardiac responses to energetic, oxidative, and genotoxic stress.
    Gratia S; Kay L; Potenza L; Seffouh A; Novel-Chaté V; Schnebelen C; Sestili P; Schlattner U; Tokarska-Schlattner M
    Cardiovasc Res; 2012 Aug; 95(3):290-9. PubMed ID: 22461523
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Apoptotic efficacy of etomoxir in human acute myeloid leukemia cells. Cooperation with arsenic trioxide and glycolytic inhibitors, and regulation by oxidative stress and protein kinase activities.
    Estañ MC; Calviño E; Calvo S; Guillén-Guío B; Boyano-Adánez Mdel C; de Blas E; Rial E; Aller P
    PLoS One; 2014; 9(12):e115250. PubMed ID: 25506699
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK).
    Sánchez Y; Amrán D; Fernández C; de Blas E; Aller P
    Int J Cancer; 2008 Sep; 123(5):1205-14. PubMed ID: 18546268
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
    Ramos AM; Fernandez C; Amrán D; Esteban D; de Blas E; Palacios MA; Aller P
    J Cell Physiol; 2006 Dec; 209(3):1006-15. PubMed ID: 16972261
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4) Protein kinase modulation and reactive oxygen species generation.
    Sánchez Y; Amrán D; de Blas E; Aller P
    Biochem Pharmacol; 2009 Feb; 77(3):384-96. PubMed ID: 19038232
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 5'-AMP-activated protein kinase attenuates adriamycin-induced oxidative podocyte injury through thioredoxin-mediated suppression of the apoptosis signal-regulating kinase 1-P38 signaling pathway.
    Gao K; Chi Y; Sun W; Takeda M; Yao J
    Mol Pharmacol; 2014 Mar; 85(3):460-71. PubMed ID: 24378334
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.
    Wlodarski P; Kasprzycka M; Liu X; Marzec M; Robertson ES; Slupianek A; Wasik MA
    Cancer Res; 2005 Sep; 65(17):7800-8. PubMed ID: 16140948
    [TBL] [Abstract][Full Text] [Related]  

  • 19. AMP-activated protein kinase couples 3-bromopyruvate-induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins.
    Bodur C; Karakas B; Timucin AC; Tezil T; Basaga H
    Mol Carcinog; 2016 Nov; 55(11):1584-1597. PubMed ID: 26373689
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Signal transduction pathways in Burkitt's lymphoma cell lines BL41 and DG75 with different sensitivity to doxorubicin.
    Shlapatska LM; Berdova GG; Kovalevska LM; Kulyk GI; Klein G; Sidorenko SP; Chekhun VF
    Exp Oncol; 2004 Sep; 26(3):210-6. PubMed ID: 15494689
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.