These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 24323786)

  • 1. Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2.
    Schroeder CI; Rash LD; Vila-Farrés X; Rosengren KJ; Mobli M; King GF; Alewood PF; Craik DJ; Durek T
    Angew Chem Int Ed Engl; 2014 Jan; 53(4):1017-20. PubMed ID: 24323786
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
    Mourier G; Salinas M; Kessler P; Stura EA; Leblanc M; Tepshi L; Besson T; Diochot S; Baron A; Douguet D; Lingueglia E; Servent D
    J Biol Chem; 2016 Feb; 291(6):2616-29. PubMed ID: 26680001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat acid-sensing ion channel 1a.
    Salinas M; Kessler P; Douguet D; Sarraf D; Tonali N; Thai R; Servent D; Lingueglia E
    Neuropharmacology; 2021 Mar; 185():108453. PubMed ID: 33450275
    [TBL] [Abstract][Full Text] [Related]  

  • 4. One-pot hydrazide-based native chemical ligation for efficient chemical synthesis and structure determination of toxin Mambalgin-1.
    Pan M; He Y; Wen M; Wu F; Sun D; Li S; Zhang L; Li Y; Tian C
    Chem Commun (Camb); 2014 Jun; 50(44):5837-9. PubMed ID: 24619065
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Binding site and inhibitory mechanism of the mambalgin-2 pain-relieving peptide on acid-sensing ion channel 1a.
    Salinas M; Besson T; Delettre Q; Diochot S; Boulakirba S; Douguet D; Lingueglia E
    J Biol Chem; 2014 May; 289(19):13363-73. PubMed ID: 24695733
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Total synthesis of mambalgin-1/2/3 by two-segment hydrazide-based native chemical ligation.
    Lan H; Wu K; Zheng Y; Pan M; Huang YC; Gao S; Zheng QY; Zheng JS; Li YM; Xiao B; Liu L
    J Pept Sci; 2016 May; 22(5):320-6. PubMed ID: 26991634
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Revealing molecular determinants governing mambalgin-3 pharmacology at acid-sensing ion channel 1 variants.
    Cristofori-Armstrong B; Budusan E; Smith JJ; Reynaud S; Voll K; Chassagnon IR; Durek T; Rash LD
    Cell Mol Life Sci; 2024 Jun; 81(1):266. PubMed ID: 38880807
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Black mamba venom peptides target acid-sensing ion channels to abolish pain.
    Diochot S; Baron A; Salinas M; Douguet D; Scarzello S; Dabert-Gay AS; Debayle D; Friend V; Alloui A; Lazdunski M; Lingueglia E
    Nature; 2012 Oct; 490(7421):552-5. PubMed ID: 23034652
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological modulation of Acid-Sensing Ion Channels 1a and 3 by amiloride and 2-guanidine-4-methylquinazoline (GMQ).
    Besson T; Lingueglia E; Salinas M
    Neuropharmacology; 2017 Oct; 125():429-440. PubMed ID: 28802647
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery and molecular interaction studies of a highly stable, tarantula peptide modulator of acid-sensing ion channel 1.
    Er SY; Cristofori-Armstrong B; Escoubas P; Rash LD
    Neuropharmacology; 2017 Dec; 127():185-195. PubMed ID: 28327374
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cryo-EM structure of the ASIC1a-mambalgin-1 complex reveals that the peptide toxin mambalgin-1 inhibits acid-sensing ion channels through an unusual allosteric effect.
    Sun D; Yu Y; Xue X; Pan M; Wen M; Li S; Qu Q; Li X; Zhang L; Li X; Liu L; Yang M; Tian C
    Cell Discov; 2018; 4():27. PubMed ID: 29872539
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: Importance of interactions at the channel subunit interface and potential for engineering selective analogues.
    Cristofori-Armstrong B; Saez NJ; Chassagnon IR; King GF; Rash LD
    Biochem Pharmacol; 2019 May; 163():381-390. PubMed ID: 30849303
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Site-specific fluorescence spectrum detection and characterization of hASIC1a channels upon toxin mambalgin-1 binding in live mammalian cells.
    Wen M; Guo X; Sun P; Xiao L; Li J; Xiong Y; Bao J; Xue T; Zhang L; Tian C
    Chem Commun (Camb); 2015 May; 51(38):8153-6. PubMed ID: 25873388
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1.
    Sun D; Liu S; Li S; Zhang M; Yang F; Wen M; Shi P; Wang T; Pan M; Chang S; Zhang X; Zhang L; Tian C; Liu L
    Elife; 2020 Sep; 9():. PubMed ID: 32915133
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mambalgins, the Venom-origin Peptides as a Potentially Novel Group of Analgesics: Mini Review.
    Brzezicki MA; Zakowicz PT
    CNS Neurol Disord Drug Targets; 2018; 17(2):87-97. PubMed ID: 29268691
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of Action of the Peptide Toxins Targeting Human and Rodent Acid-Sensing Ion Channels and Relevance to Their In Vivo Analgesic Effects.
    Verkest C; Salinas M; Diochot S; Deval E; Lingueglia E; Baron A
    Toxins (Basel); 2022 Oct; 14(10):. PubMed ID: 36287977
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Venom toxins in the exploration of molecular, physiological and pathophysiological functions of acid-sensing ion channels.
    Baron A; Diochot S; Salinas M; Deval E; Noël J; Lingueglia E
    Toxicon; 2013 Dec; 75():187-204. PubMed ID: 23624383
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Taking a bite out of pain: snake venom can be both a curse and a cure when targeting acid sensing ion channels (ASICs) in the pain pathway.
    Bladen C
    Channels (Austin); 2013; 7(2):69-70. PubMed ID: 23449234
    [No Abstract]   [Full Text] [Related]  

  • 19. Mambalgin-3 potentiates human acid-sensing ion channel 1b under mild to moderate acidosis: Implications as an analgesic lead.
    Cristofori-Armstrong B; Budusan E; Rash LD
    Proc Natl Acad Sci U S A; 2021 Feb; 118(8):. PubMed ID: 33602819
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional and pharmacological characterization of two different ASIC1a/2a heteromers reveals their sensitivity to the spider toxin PcTx1.
    Joeres N; Augustinowski K; Neuhof A; Assmann M; Gründer S
    Sci Rep; 2016 Jun; 6():27647. PubMed ID: 27277303
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.