BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 24329001)

  • 21. Resveratrol enhances the sensitivity of FL118 in triple-negative breast cancer cell lines via suppressing epithelial to mesenchymal transition.
    Yar Saglam AS; Kayhan H; Alp E; Onen HI
    Mol Biol Rep; 2021 Jan; 48(1):475-489. PubMed ID: 33389483
    [TBL] [Abstract][Full Text] [Related]  

  • 22. ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth.
    Ward GA; Lewis EJ; Ahn JS; Johnson CN; Lyons JF; Martins V; Munck JM; Rich SJ; Smyth T; Thompson NT; Williams PA; Wilsher NE; Wallis NG; Chessari G
    Mol Cancer Ther; 2018 Jul; 17(7):1381-1391. PubMed ID: 29695633
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-XL and survivin.
    Momeny M; Zakidizaji M; Ghasemi R; Dehpour AR; Rahimi-Balaei M; Abdolazimi Y; Ghavamzadeh A; Alimoghaddam K; Ghaffari SH
    Med Oncol; 2010 Sep; 27(3):833-42. PubMed ID: 19763917
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Nonpeptidic and potent small-molecule inhibitors of cIAP-1/2 and XIAP proteins.
    Sun H; Lu J; Liu L; Yi H; Qiu S; Yang CY; Deschamps JR; Wang S
    J Med Chem; 2010 Sep; 53(17):6361-7. PubMed ID: 20684551
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex.
    Arora V; Cheung HH; Plenchette S; Micali OC; Liston P; Korneluk RG
    J Biol Chem; 2007 Sep; 282(36):26202-9. PubMed ID: 17613533
    [TBL] [Abstract][Full Text] [Related]  

  • 26. FL118, a novel survivin inhibitor, wins the battle against drug-resistant and metastatic lung cancers through inhibition of cancer stem cell-like properties.
    Wang J; Liu Z; Zhang D; Liu R; Lin Q; Liu J; Yang Z; Ma Q; Sun D; Zhou X; Jiang G
    Am J Transl Res; 2017; 9(8):3676-3686. PubMed ID: 28861158
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Simultaneous determination of FL118 and W34 in rat Blood by LC-MS/MS: Application to pharmacokinetic studies.
    Feng K; Zhang J; Zhang Y; Jiang T; Lv Z; Yu M
    Biomed Chromatogr; 2020 Nov; 34(11):e4944. PubMed ID: 32639034
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Hydroxycamptothecin induces apoptosis and inhibits tumor growth in colon cancer by the downregulation of survivin and XIAP expression.
    Fei B; Chi AL; Weng Y
    World J Surg Oncol; 2013 May; 11():120. PubMed ID: 23721525
    [TBL] [Abstract][Full Text] [Related]  

  • 29. p53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression of XIAP expression.
    Kim SH; Singh SV
    Cancer Prev Res (Phila); 2010 Jun; 3(6):718-26. PubMed ID: 20484174
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors.
    Wang J; Li W
    J Pharmacol Exp Ther; 2014 May; 349(2):319-29. PubMed ID: 24623800
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design, synthesis, and biological evaluation of novel 7-substituted 10,11-methylenedioxy-camptothecin derivatives against drug-resistant small-cell lung cancer in vitro and in vivo.
    Zhang G; Yin R; Dai X; Wu G; Qi X; Yu R; Li J; Jiang T
    Eur J Med Chem; 2022 Nov; 241():114610. PubMed ID: 35932565
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Studies on indolizines. Evaluation of their biological properties as microtubule-interacting agents and as melanoma targeting compounds.
    Ghinet A; Abuhaie CM; Gautret P; Rigo B; Dubois J; Farce A; Belei D; Bîcu E
    Eur J Med Chem; 2015 Jan; 89():115-27. PubMed ID: 25462232
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Topotecan triggers apoptosis in p53-deficient cells by forcing degradation of XIAP and survivin thereby activating caspase-3-mediated Bid cleavage.
    Tomicic MT; Christmann M; Kaina B
    J Pharmacol Exp Ther; 2010 Jan; 332(1):316-25. PubMed ID: 19812371
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Potent and selective small-molecule inhibitors of cIAP1/2 proteins reveal that the binding of Smac mimetics to XIAP BIR3 is not required for their effective induction of cell death in tumor cells.
    Sun H; Lu J; Liu L; Yang CY; Wang S
    ACS Chem Biol; 2014 Apr; 9(4):994-1002. PubMed ID: 24521431
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma.
    Holthof LC; van der Horst HJ; van Hal-van Veen SE; Ruiter RWJ; Li F; Buijze M; Andersen MN; Yuan H; de Bruijn J; van de Donk NWCJ; Lokhorst HM; Zweegman S; Groen RWJ; Mutis T
    Haematologica; 2020; 105(2):e80-e83. PubMed ID: 31123033
    [No Abstract]   [Full Text] [Related]  

  • 36. Melatonin overcomes apoptosis resistance in human hepatocellular carcinoma by targeting survivin and XIAP.
    Fan L; Sun G; Ma T; Zhong F; Wei W
    J Pineal Res; 2013 Sep; 55(2):174-83. PubMed ID: 23679681
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis, characterization and biological evaluation of anti-cancer indolizine derivatives via inhibiting β-catenin activity and activating p53.
    Moon SH; Jung Y; Kim SH; Kim I
    Bioorg Med Chem Lett; 2016 Jan; 26(1):110-3. PubMed ID: 26608553
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Lentivirus-mediated shRNA targeting XIAP and survivin inhibit SW1990 pancreatic cancer cell proliferation in vitro and in vivo.
    Jiang C; Tan T; Yi XP; Shen H; Li YX
    Mol Med Rep; 2011; 4(4):667-74. PubMed ID: 21479361
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.
    Donnell AF; Michoud C; Rupert KC; Han X; Aguilar D; Frank KB; Fretland AJ; Gao L; Goggin B; Hogg JH; Hong K; Janson CA; Kester RF; Kong N; Le K; Li S; Liang W; Lombardo LJ; Lou Y; Lukacs CM; Mischke S; Moliterni JA; Polonskaia A; Schutt AD; Solis DS; Specian A; Taylor RT; Weisel M; Remiszewski SW
    J Med Chem; 2013 Oct; 56(20):7772-87. PubMed ID: 24083782
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Ciglitazone induces caspase-independent apoptosis through down-regulation of XIAP and survivin in human glioma cells.
    Kang DW; Choi CH; Park JY; Kang SK; Kim YK
    Neurochem Res; 2008 Mar; 33(3):551-61. PubMed ID: 17940898
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.