80 related articles for article (PubMed ID: 24336137)
1. Improving the assessment of heart toxicity for all new drugs through translational regulatory science.
Johannesen L; Vicente J; Gray RA; Galeotti L; Loring Z; Garnett CE; Florian J; Ugander M; Stockbridge N; Strauss DG
Clin Pharmacol Ther; 2014 May; 95(5):501-8. PubMed ID: 24336137
[TBL] [Abstract][Full Text] [Related]
2. Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block.
Vicente J; Johannesen L; Hosseini M; Mason JW; Sager PT; Pueyo E; Strauss DG
PLoS One; 2016; 11(12):e0163619. PubMed ID: 28036334
[TBL] [Abstract][Full Text] [Related]
3. Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Mirams GR; Cui Y; Sher A; Fink M; Cooper J; Heath BM; McMahon NC; Gavaghan DJ; Noble D
Cardiovasc Res; 2011 Jul; 91(1):53-61. PubMed ID: 21300721
[TBL] [Abstract][Full Text] [Related]
4. Stereoselective Inhibition of the hERG1 Potassium Channel.
Grilo LS; Carrupt PA; Abriel H
Front Pharmacol; 2010; 1():137. PubMed ID: 21833176
[TBL] [Abstract][Full Text] [Related]
5. Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil.
Johannesen L; Vicente J; Mason JW; Sanabria C; Waite-Labott K; Hong M; Guo P; Lin J; Sørensen JS; Galeotti L; Florian J; Ugander M; Stockbridge N; Strauss DG
Clin Pharmacol Ther; 2014 Nov; 96(5):549-58. PubMed ID: 25054430
[TBL] [Abstract][Full Text] [Related]
6. Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trial.
Johannesen L; Vicente J; Mason JW; Erato C; Sanabria C; Waite-Labott K; Hong M; Lin J; Guo P; Mutlib A; Wang J; Crumb WJ; Blinova K; Chan D; Stohlman J; Florian J; Ugander M; Stockbridge N; Strauss DG
Clin Pharmacol Ther; 2016 Feb; 99(2):214-23. PubMed ID: 26259627
[TBL] [Abstract][Full Text] [Related]
7. Comprehensive T wave morphology assessment in a randomized clinical study of dofetilide, quinidine, ranolazine, and verapamil.
Vicente J; Johannesen L; Mason JW; Crumb WJ; Pueyo E; Stockbridge N; Strauss DG
J Am Heart Assoc; 2015 Apr; 4(4):. PubMed ID: 25870186
[TBL] [Abstract][Full Text] [Related]
8. New science, drug regulation, and emergent public health issues: The work of FDA's division of applied regulatory science.
Chiu K; Racz R; Burkhart K; Florian J; Ford K; Iveth Garcia M; Geiger RM; Howard KE; Hyland PL; Ismaiel OA; Kruhlak NL; Li Z; Matta MK; Prentice KW; Shah A; Stavitskaya L; Volpe DA; Weaver JL; Wu WW; Rouse R; Strauss DG
Front Med (Lausanne); 2022; 9():1109541. PubMed ID: 36743666
[TBL] [Abstract][Full Text] [Related]
9. Human Induced Pluripotent Stem Cell as a Disease Modeling and Drug Development Platform-A Cardiac Perspective.
Bekhite MM; Schulze PC
Cells; 2021 Dec; 10(12):. PubMed ID: 34943991
[TBL] [Abstract][Full Text] [Related]
10. Concentration-QT modelling of the novel DHFR inhibitor P218 in healthy male volunteers.
Täubel J; Lorch U; Ferber G; Spencer CS; Freier A; Coates S; El Gaaloul M; Donini C; Chughlay MF; Chalon S
Br J Clin Pharmacol; 2022 Jan; 88(1):128-137. PubMed ID: 34075612
[TBL] [Abstract][Full Text] [Related]
11. Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter.
Mendzelevski B; Spencer CS; Freier A; Camilleri D; Graff C; Täubel J
Ann Noninvasive Electrocardiol; 2021 Sep; 26(5):e12851. PubMed ID: 33949017
[TBL] [Abstract][Full Text] [Related]
12. Intense bitterness of molecules: Machine learning for expediting drug discovery.
Margulis E; Dagan-Wiener A; Ives RS; Jaffari S; Siems K; Niv MY
Comput Struct Biotechnol J; 2021; 19():568-576. PubMed ID: 33510862
[TBL] [Abstract][Full Text] [Related]
13. Translational Models and Tools to Reduce Clinical Trials and Improve Regulatory Decision Making for QTc and Proarrhythmia Risk (ICH E14/S7B Updates).
Strauss DG; Wu WW; Li Z; Koerner J; Garnett C
Clin Pharmacol Ther; 2021 Feb; 109(2):319-333. PubMed ID: 33332579
[TBL] [Abstract][Full Text] [Related]
14. The association between body temperature and electrocardiographic parameters in normothermic healthy volunteers.
Fienieg B; Hassing GJ; van der Wall HEC; van Westen GJP; Kemme MJB; Adiyaman A; Elvan A; Burggraaf J; Gal P
Pacing Clin Electrophysiol; 2021 Jan; 44(1):44-53. PubMed ID: 33179782
[TBL] [Abstract][Full Text] [Related]
15. Transdermal Testosterone Attenuates Drug-Induced Lengthening of Both Early and Late Ventricular Repolarization in Older Men.
Tomaselli Muensterman E; Jaynes HA; Sowinski KM; Overholser BR; Shen C; Kovacs RJ; Tisdale JE
Clin Pharmacol Ther; 2021 Jun; 109(6):1499-1504. PubMed ID: 33020898
[TBL] [Abstract][Full Text] [Related]
16. Discovery of Vixotrigine: A Novel Use-Dependent Sodium Channel Blocker for the Treatment of Trigeminal Neuralgia.
Witty DR; Alvaro G; Derjean D; Giblin GMP; Gunn K; Large C; Macpherson DT; Morisset V; Owen D; Palmer J; Rugiero F; Tate S; Hinckley CA; Naik H
ACS Med Chem Lett; 2020 Sep; 11(9):1678-1687. PubMed ID: 32945812
[TBL] [Abstract][Full Text] [Related]
17. Effects of the Fluoroquinolones Moxifloxacin and Levofloxacin on the QT Subintervals: Sex Differences in Ventricular Repolarization.
Täubel J; Prasad K; Rosano G; Ferber G; Wibberley H; Cole ST; Van Langenhoven L; Fernandes S; Djumanov D; Sugiyama A
J Clin Pharmacol; 2020 Mar; 60(3):400-408. PubMed ID: 31637733
[TBL] [Abstract][Full Text] [Related]
18. Heart Rate Correction of the J-to-Tpeak Interval.
Hnatkova K; Vicente J; Johannesen L; Garnett C; Strauss DG; Stockbridge N; Malik M
Sci Rep; 2019 Oct; 9(1):15060. PubMed ID: 31636317
[TBL] [Abstract][Full Text] [Related]
19. Three-Dimensional Heart Model-Based Screening of Proarrhythmic Potential by
Hwang M; Han S; Park MC; Leem CH; Shim EB; Yim DS
Front Physiol; 2019; 10():1139. PubMed ID: 31551815
[TBL] [Abstract][Full Text] [Related]
20.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
[Next] [New Search]