These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

339 related articles for article (PubMed ID: 24337568)

  • 1. Organization of the mitochondrial apoptotic BAK pore: oligomerization of the BAK homodimers.
    Aluvila S; Mandal T; Hustedt E; Fajer P; Choe JY; Oh KJ
    J Biol Chem; 2014 Jan; 289(5):2537-51. PubMed ID: 24337568
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3-BH3 contact interface in BAK homo-oligomers.
    Oh KJ; Singh P; Lee K; Foss K; Lee S; Park M; Lee S; Aluvila S; Park M; Singh P; Kim RS; Symersky J; Walters DE
    J Biol Chem; 2010 Sep; 285(37):28924-37. PubMed ID: 20605789
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane.
    Westphal D; Dewson G; Menard M; Frederick P; Iyer S; Bartolo R; Gibson L; Czabotar PE; Smith BJ; Adams JM; Kluck RM
    Proc Natl Acad Sci U S A; 2014 Sep; 111(39):E4076-85. PubMed ID: 25228770
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Assembly of Bak homodimers into higher order homooligomers in the mitochondrial apoptotic pore.
    Mandal T; Shin S; Aluvila S; Chen HC; Grieve C; Choe JY; Cheng EH; Hustedt EJ; Oh KJ
    Sci Rep; 2016 Aug; 6():30763. PubMed ID: 27488021
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis.
    Ma S; Hockings C; Anwari K; Kratina T; Fennell S; Lazarou M; Ryan MT; Kluck RM; Dewson G
    J Biol Chem; 2013 Sep; 288(36):26027-26038. PubMed ID: 23893415
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis.
    Dewson G; Kluck RM
    J Cell Sci; 2009 Aug; 122(Pt 16):2801-8. PubMed ID: 19795525
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains.
    Iyer S; Bell F; Westphal D; Anwari K; Gulbis J; Smith BJ; Dewson G; Kluck RM
    Cell Death Differ; 2015 Oct; 22(10):1665-75. PubMed ID: 25744027
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove.
    Li MX; Tan IKL; Ma SB; Hockings C; Kratina T; Dengler MA; Alsop AE; Kluck RM; Dewson G
    Proc Natl Acad Sci U S A; 2017 Jul; 114(29):7629-7634. PubMed ID: 28673969
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct activation of full-length proapoptotic BAK.
    Leshchiner ES; Braun CR; Bird GH; Walensky LD
    Proc Natl Acad Sci U S A; 2013 Mar; 110(11):E986-95. PubMed ID: 23404709
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes.
    Zhang Z; Subramaniam S; Kale J; Liao C; Huang B; Brahmbhatt H; Condon SG; Lapolla SM; Hays FA; Ding J; He F; Zhang XC; Li J; Senes A; Andrews DW; Lin J
    EMBO J; 2016 Jan; 35(2):208-36. PubMed ID: 26702098
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the α1-α2 loop in BAK activation.
    Robin AY; Miller MS; Iyer S; Shi MX; Wardak AZ; Lio D; Smith NA; Smith BJ; Birkinshaw RW; Czabotar PE; Kluck RM; Colman PM
    Cell Death Differ; 2022 Sep; 29(9):1757-1768. PubMed ID: 35279694
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Assembly of the mitochondrial apoptosis-induced channel, MAC.
    Martinez-Caballero S; Dejean LM; Kinnally MS; Oh KJ; Mannella CA; Kinnally KW
    J Biol Chem; 2009 May; 284(18):12235-45. PubMed ID: 19261612
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The multidomain proapoptotic molecules Bax and Bak are directly activated by heat.
    Pagliari LJ; Kuwana T; Bonzon C; Newmeyer DD; Tu S; Beere HM; Green DR
    Proc Natl Acad Sci U S A; 2005 Dec; 102(50):17975-80. PubMed ID: 16330765
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies.
    Iyer S; Anwari K; Alsop AE; Yuen WS; Huang DC; Carroll J; Smith NA; Smith BJ; Dewson G; Kluck RM
    Nat Commun; 2016 May; 7():11734. PubMed ID: 27217060
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bax dimerizes via a symmetric BH3:groove interface during apoptosis.
    Dewson G; Ma S; Frederick P; Hockings C; Tan I; Kratina T; Kluck RM
    Cell Death Differ; 2012 Apr; 19(4):661-70. PubMed ID: 22015607
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Death upon a kiss: mitochondrial outer membrane composition and organelle communication govern sensitivity to BAK/BAX-dependent apoptosis.
    Renault TT; Chipuk JE
    Chem Biol; 2014 Jan; 21(1):114-23. PubMed ID: 24269152
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bak core and latch domains separate during activation, and freed core domains form symmetric homodimers.
    Brouwer JM; Westphal D; Dewson G; Robin AY; Uren RT; Bartolo R; Thompson GV; Colman PM; Kluck RM; Czabotar PE
    Mol Cell; 2014 Sep; 55(6):938-946. PubMed ID: 25175025
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Topology of active, membrane-embedded Bax in the context of a toroidal pore.
    Bleicken S; Assafa TE; Stegmueller C; Wittig A; Garcia-Saez AJ; Bordignon E
    Cell Death Differ; 2018 Nov; 25(10):1717-1731. PubMed ID: 30185826
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection.
    Niu X; Brahmbhatt H; Mergenthaler P; Zhang Z; Sang J; Daude M; Ehlert FGR; Diederich WE; Wong E; Zhu W; Pogmore J; Nandy JP; Satyanarayana M; Jimmidi RK; Arya P; Leber B; Lin J; Culmsee C; Yi J; Andrews DW
    Cell Chem Biol; 2017 Apr; 24(4):493-506.e5. PubMed ID: 28392146
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pore formation by dimeric Bak and Bax: an unusual pore?
    Uren RT; Iyer S; Kluck RM
    Philos Trans R Soc Lond B Biol Sci; 2017 Aug; 372(1726):. PubMed ID: 28630157
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.