BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 24344235)

  • 1. Novel neutralizing hedgehog antibody MEDI-5304 exhibits antitumor activity by inhibiting paracrine hedgehog signaling.
    Michaud NR; Wang Y; McEachern KA; Jordan JJ; Mazzola AM; Hernandez A; Jalla S; Chesebrough JW; Hynes MJ; Belmonte MA; Wang L; Kang JS; Jovanovic J; Laing N; Jenkins DW; Hurt E; Liang M; Frantz C; Hollingsworth RE; Simeone DM; Blakey DC; Bedian V
    Mol Cancer Ther; 2014 Feb; 13(2):386-98. PubMed ID: 24344235
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sonic hedgehog paracrine signaling activates stromal cells to promote perineural invasion in pancreatic cancer.
    Li X; Wang Z; Ma Q; Xu Q; Liu H; Duan W; Lei J; Ma J; Wang X; Lv S; Han L; Li W; Guo J; Guo K; Zhang D; Wu E; Xie K
    Clin Cancer Res; 2014 Aug; 20(16):4326-38. PubMed ID: 24947933
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aberrations and therapeutics involving the developmental pathway Hedgehog in pancreatic cancer.
    Kelleher FC; McDermott R
    Vitam Horm; 2012; 88():355-78. PubMed ID: 22391312
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway.
    Li SH; Fu J; Watkins DN; Srivastava RK; Shankar S
    Mol Cell Biochem; 2013 Jan; 373(1-2):217-27. PubMed ID: 23129257
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth.
    Sharma N; Nanta R; Sharma J; Gunewardena S; Singh KP; Shankar S; Srivastava RK
    Oncotarget; 2015 Oct; 6(31):32039-60. PubMed ID: 26451606
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling.
    Ibuki N; Ghaffari M; Pandey M; Iu I; Fazli L; Kashiwagi M; Tojo H; Nakanishi O; Gleave ME; Cox ME
    Int J Cancer; 2013 Oct; 133(8):1955-66. PubMed ID: 23564295
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of platelet-derived growth factor receptor α by MEDI-575 reduces tumor growth and stromal fibroblast content in a model of non-small cell lung cancer.
    Laing N; McDermott B; Wen S; Yang D; Lawson D; Collins M; Reimer C; Hall PA; Andersén H; Snaith M; Wang X; Bedian V; Cao ZA; Blakey D
    Mol Pharmacol; 2013 Jun; 83(6):1247-56. PubMed ID: 23558446
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sanguinarine inhibits pancreatic cancer stem cell characteristics by inducing oxidative stress and suppressing sonic hedgehog-Gli-Nanog pathway.
    Ma Y; Yu W; Shrivastava A; Alemi F; Lankachandra K; Srivastava RK; Shankar S
    Carcinogenesis; 2017 Oct; 38(10):1047-1056. PubMed ID: 28968696
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer.
    Hwang RF; Moore TT; Hattersley MM; Scarpitti M; Yang B; Devereaux E; Ramachandran V; Arumugam T; Ji B; Logsdon CD; Brown JL; Godin R
    Mol Cancer Res; 2012 Sep; 10(9):1147-57. PubMed ID: 22859707
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual IGF-I/II-neutralizing antibody MEDI-573 potently inhibits IGF signaling and tumor growth.
    Gao J; Chesebrough JW; Cartlidge SA; Ricketts SA; Incognito L; Veldman-Jones M; Blakey DC; Tabrizi M; Jallal B; Trail PA; Coats S; Bosslet K; Chang YS
    Cancer Res; 2011 Feb; 71(3):1029-40. PubMed ID: 21245093
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sonic-hedgehog pathway inhibition normalizes desmoplastic tumor microenvironment to improve chemo- and nanotherapy.
    Mpekris F; Papageorgis P; Polydorou C; Voutouri C; Kalli M; Pirentis AP; Stylianopoulos T
    J Control Release; 2017 Sep; 261():105-112. PubMed ID: 28662901
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Therapeutic inhibition of Hedgehog-GLI signaling in cancer: epithelial, stromal, or stem cell targets?
    Ruiz i Altaba A
    Cancer Cell; 2008 Oct; 14(4):281-3. PubMed ID: 18835029
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
    Song L; Chen X; Wang P; Gao S; Qu C; Liu L
    Acta Biochim Biophys Sin (Shanghai); 2018 Jun; 50(6):586-596. PubMed ID: 29697746
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer.
    Bailey JM; Mohr AM; Hollingsworth MA
    Oncogene; 2009 Oct; 28(40):3513-25. PubMed ID: 19633682
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.
    Feldmann G; Fendrich V; McGovern K; Bedja D; Bisht S; Alvarez H; Koorstra JB; Habbe N; Karikari C; Mullendore M; Gabrielson KL; Sharma R; Matsui W; Maitra A
    Mol Cancer Ther; 2008 Sep; 7(9):2725-35. PubMed ID: 18790753
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice.
    Büller NV; Rosekrans SL; Metcalfe C; Heijmans J; van Dop WA; Fessler E; Jansen M; Ahn C; Vermeulen JL; Westendorp BF; Robanus-Maandag EC; Offerhaus GJ; Medema JP; D'Haens GR; Wildenberg ME; de Sauvage FJ; Muncan V; van den Brink GR
    Gastroenterology; 2015 Jan; 148(1):170-180.e6. PubMed ID: 25307863
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Berberine inhibits colorectal tumor growth by suppressing SHH secretion.
    Shen ZQ; Wang J; Tan WF; Huang TM
    Acta Pharmacol Sin; 2021 Jul; 42(7):1190-1194. PubMed ID: 32958873
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition.
    Kangwan N; Kim YJ; Han YM; Jeong M; Park JM; Go EJ; Hahm KB
    Oncotarget; 2016 Feb; 7(7):7667-82. PubMed ID: 26716648
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.
    Oberst MD; Fuhrmann S; Mulgrew K; Amann M; Cheng L; Lutterbuese P; Richman L; Coats S; Baeuerle PA; Hammond SA
    MAbs; 2014; 6(6):1571-84. PubMed ID: 25484061
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rationale for inhibition of the hedgehog pathway paracrine loop in pancreatic adenocarcinoma.
    Dimou A; Syrigos K; Saif MW
    JOP; 2011 Jan; 12(1):1-5. PubMed ID: 21206093
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.