174 related articles for article (PubMed ID: 24345794)
1. Evaluation of the use of Classical Nucleation Theory for predicting intestinal crystalline precipitation of two weakly basic BSC class II drugs.
Carlert S; Lennernäs H; Abrahamsson B
Eur J Pharm Sci; 2014 Mar; 53():17-27. PubMed ID: 24345794
[TBL] [Abstract][Full Text] [Related]
2. In vivo dog intestinal precipitation of mebendazole: a basic BCS class II drug.
Carlert S; Akesson P; Jerndal G; Lindfors L; Lennernäs H; Abrahamsson B
Mol Pharm; 2012 Oct; 9(10):2903-11. PubMed ID: 22954025
[TBL] [Abstract][Full Text] [Related]
3. Predicting intestinal precipitation--a case example for a basic BCS class II drug.
Carlert S; Pålsson A; Hanisch G; von Corswant C; Nilsson C; Lindfors L; Lennernäs H; Abrahamsson B
Pharm Res; 2010 Oct; 27(10):2119-30. PubMed ID: 20717839
[TBL] [Abstract][Full Text] [Related]
4. In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: application of the mechanistic absorption model GI-Sim.
Sjögren E; Westergren J; Grant I; Hanisch G; Lindfors L; Lennernäs H; Abrahamsson B; Tannergren C
Eur J Pharm Sci; 2013 Jul; 49(4):679-98. PubMed ID: 23727464
[TBL] [Abstract][Full Text] [Related]
5. Precipitation in the small intestine may play a more important role in the in vivo performance of poorly soluble weak bases in the fasted state: case example nelfinavir.
Shono Y; Jantratid E; Dressman JB
Eur J Pharm Biopharm; 2011 Oct; 79(2):349-56. PubMed ID: 21527341
[TBL] [Abstract][Full Text] [Related]
6. A simulation of oral absorption using classical nucleation theory.
Sugano K
Int J Pharm; 2009 Aug; 378(1-2):142-5. PubMed ID: 19501145
[TBL] [Abstract][Full Text] [Related]
7. Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer model tests coupled with a physiologically based pharmacokinetic model.
Wagner C; Jantratid E; Kesisoglou F; Vertzoni M; Reppas C; B Dressman J
Eur J Pharm Biopharm; 2012 Sep; 82(1):127-38. PubMed ID: 22652546
[TBL] [Abstract][Full Text] [Related]
8. Prediction of the precipitation profiles of weak base drugs in the small intestine using a simplified transfer ("dumping") model coupled with in silico modeling and simulation approach.
Kambayashi A; Yasuji T; Dressman JB
Eur J Pharm Biopharm; 2016 Jun; 103():95-103. PubMed ID: 27012902
[TBL] [Abstract][Full Text] [Related]
9. An in vitro methodology for forecasting luminal concentrations and precipitation of highly permeable lipophilic weak bases in the fasted upper small intestine.
Psachoulias D; Vertzoni M; Butler J; Busby D; Symillides M; Dressman J; Reppas C
Pharm Res; 2012 Dec; 29(12):3486-98. PubMed ID: 22890986
[TBL] [Abstract][Full Text] [Related]
10. In Vitro, in Silico, and in Vivo Assessments of Intestinal Precipitation and Its Impact on Bioavailability of a BCS Class 2 Basic Compound.
Kou D; Zhang C; Yiu H; Ng T; Lubach JW; Janson M; Mao C; Durk M; Chinn L; Winter H; Wigman L; Yehl P
Mol Pharm; 2018 Apr; 15(4):1607-1617. PubMed ID: 29522347
[TBL] [Abstract][Full Text] [Related]
11. Predicting the precipitation of poorly soluble weak bases upon entry in the small intestine.
Kostewicz ES; Wunderlich M; Brauns U; Becker R; Bock T; Dressman JB
J Pharm Pharmacol; 2004 Jan; 56(1):43-51. PubMed ID: 14980000
[TBL] [Abstract][Full Text] [Related]
12. Prediction of the human oral bioavailability by using in vitro and in silico drug related parameters in a physiologically based absorption model.
Paixão P; Gouveia LF; Morais JA
Int J Pharm; 2012 Jun; 429(1-2):84-98. PubMed ID: 22449410
[TBL] [Abstract][Full Text] [Related]
13. Effects of structural modifications on the intestinal permeability of angiotensin II receptor antagonists and the correlation of in vitro, in situ, and in vivo absorption.
Ribadeneira MD; Aungst BJ; Eyermann CJ; Huang SM
Pharm Res; 1996 Feb; 13(2):227-33. PubMed ID: 8932441
[TBL] [Abstract][Full Text] [Related]
14. Analysis of the enhanced oral bioavailability of fenofibrate lipid formulations in fasted humans using an in vitro-in silico-in vivo approach.
Fei Y; Kostewicz ES; Sheu MT; Dressman JB
Eur J Pharm Biopharm; 2013 Nov; 85(3 Pt B):1274-84. PubMed ID: 23500116
[TBL] [Abstract][Full Text] [Related]
15. In vitro-in vivo correlation of the effect of supersaturation on the intestinal absorption of BCS Class 2 drugs.
Higashino H; Hasegawa T; Yamamoto M; Matsui R; Masaoka Y; Kataoka M; Sakuma S; Yamashita S
Mol Pharm; 2014 Mar; 11(3):746-54. PubMed ID: 24460473
[TBL] [Abstract][Full Text] [Related]
16. Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs.
Patel S; Zhu W; Xia B; Sharma N; Hermans A; Ehrick JD; Kesisoglou F; Pennington J
J Pharm Sci; 2019 Jan; 108(1):574-583. PubMed ID: 30395833
[TBL] [Abstract][Full Text] [Related]
17. Quantitative analysis of the effect of supersaturation on in vivo drug absorption.
Takano R; Takata N; Saito R; Furumoto K; Higo S; Hayashi Y; Machida M; Aso Y; Yamashita S
Mol Pharm; 2010 Oct; 7(5):1431-40. PubMed ID: 20704264
[TBL] [Abstract][Full Text] [Related]
18. A strategy for preclinical formulation development using GastroPlus as pharmacokinetic simulation tool and a statistical screening design applied to a dog study.
Kuentz M; Nick S; Parrott N; Röthlisberger D
Eur J Pharm Sci; 2006 Jan; 27(1):91-9. PubMed ID: 16219449
[TBL] [Abstract][Full Text] [Related]
19. Prediction of human pharmacokinetics--gastrointestinal absorption.
Fagerholm U
J Pharm Pharmacol; 2007 Jul; 59(7):905-16. PubMed ID: 17637184
[TBL] [Abstract][Full Text] [Related]
20. Dissolution media simulating the proximal canine gastrointestinal tract in the fasted state.
Arndt M; Chokshi H; Tang K; Parrott NJ; Reppas C; Dressman JB
Eur J Pharm Biopharm; 2013 Aug; 84(3):633-41. PubMed ID: 23434923
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]