232 related articles for article (PubMed ID: 24349418)
21. Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes.
Matsa E; Dixon JE; Medway C; Georgiou O; Patel MJ; Morgan K; Kemp PJ; Staniforth A; Mellor I; Denning C
Eur Heart J; 2014 Apr; 35(16):1078-87. PubMed ID: 23470493
[TBL] [Abstract][Full Text] [Related]
22. Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome.
Yazawa M; Hsueh B; Jia X; Pasca AM; Bernstein JA; Hallmayer J; Dolmetsch RE
Nature; 2011 Mar; 471(7337):230-4. PubMed ID: 21307850
[TBL] [Abstract][Full Text] [Related]
23. alpha-1-syntrophin mutation and the long-QT syndrome: a disease of sodium channel disruption.
Wu G; Ai T; Kim JJ; Mohapatra B; Xi Y; Li Z; Abbasi S; Purevjav E; Samani K; Ackerman MJ; Qi M; Moss AJ; Shimizu W; Towbin JA; Cheng J; Vatta M
Circ Arrhythm Electrophysiol; 2008 Aug; 1(3):193-201. PubMed ID: 19684871
[TBL] [Abstract][Full Text] [Related]
24. Modeling long QT syndromes using induced pluripotent stem cells: current progress and future challenges.
Friedrichs S; Malan D; Sasse P
Trends Cardiovasc Med; 2013 May; 23(4):91-8. PubMed ID: 23266156
[TBL] [Abstract][Full Text] [Related]
25. [Molecular genetics in the hereditary form of long QT syndrome].
Georgijević Milić L
Med Pregl; 2000; 53(1-2):51-4. PubMed ID: 10953551
[TBL] [Abstract][Full Text] [Related]
26. Allele-specific ablation rescues electrophysiological abnormalities in a human iPS cell model of long-QT syndrome with a CALM2 mutation.
Yamamoto Y; Makiyama T; Harita T; Sasaki K; Wuriyanghai Y; Hayano M; Nishiuchi S; Kohjitani H; Hirose S; Chen J; Yokoi F; Ishikawa T; Ohno S; Chonabayashi K; Motomura H; Yoshida Y; Horie M; Makita N; Kimura T
Hum Mol Genet; 2017 May; 26(9):1670-1677. PubMed ID: 28335032
[TBL] [Abstract][Full Text] [Related]
27. Patient-independent human induced pluripotent stem cell model: A new tool for rapid determination of genetic variant pathogenicity in long QT syndrome.
Chavali NV; Kryshtal DO; Parikh SS; Wang L; Glazer AM; Blackwell DJ; Kroncke BM; Shoemaker MB; Knollmann BC
Heart Rhythm; 2019 Nov; 16(11):1686-1695. PubMed ID: 31004778
[TBL] [Abstract][Full Text] [Related]
28. Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome.
Vatta M; Ackerman MJ; Ye B; Makielski JC; Ughanze EE; Taylor EW; Tester DJ; Balijepalli RC; Foell JD; Li Z; Kamp TJ; Towbin JA
Circulation; 2006 Nov; 114(20):2104-12. PubMed ID: 17060380
[TBL] [Abstract][Full Text] [Related]
29. Characterization of human cardiac Na+ channel mutations in the congenital long QT syndrome.
Wang DW; Yazawa K; George AL; Bennett PB
Proc Natl Acad Sci U S A; 1996 Nov; 93(23):13200-5. PubMed ID: 8917568
[TBL] [Abstract][Full Text] [Related]
30. A heterozygous deletion mutation in the cardiac sodium channel gene SCN5A with loss- and gain-of-function characteristics manifests as isolated conduction disease, without signs of Brugada or long QT syndrome.
Zumhagen S; Veldkamp MW; Stallmeyer B; Baartscheer A; Eckardt L; Paul M; Remme CA; Bhuiyan ZA; Bezzina CR; Schulze-Bahr E
PLoS One; 2013; 8(6):e67963. PubMed ID: 23840796
[TBL] [Abstract][Full Text] [Related]
31. Digenic inheritance novel mutations in SCN5a and SNTA1 increase late I(Na) contributing to LQT syndrome.
Hu RM; Tan BH; Orland KM; Valdivia CR; Peterson A; Pu J; Makielski JC
Am J Physiol Heart Circ Physiol; 2013 Apr; 304(7):H994-H1001. PubMed ID: 23376825
[TBL] [Abstract][Full Text] [Related]
32. Cardiac sodium channel mutation associated with epinephrine-induced QT prolongation and sinus node dysfunction.
Chen J; Makiyama T; Wuriyanghai Y; Ohno S; Sasaki K; Hayano M; Harita T; Nishiuchi S; Yuta Yamamoto ; Ueyama T; Shimizu A; Horie M; Kimura T
Heart Rhythm; 2016 Jan; 13(1):289-98. PubMed ID: 26282245
[TBL] [Abstract][Full Text] [Related]
33. The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT.
Mechakra A; Vincent Y; Chevalier P; Millat G; Ficker E; Jastrzebski M; Poulin H; Pouliot V; Chahine M; Christé G
Gene; 2014 Feb; 536(2):348-56. PubMed ID: 24334129
[TBL] [Abstract][Full Text] [Related]
34. The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity.
Song W; Xiao Y; Chen H; Ashpole NM; Piekarz AD; Ma P; Hudmon A; Cummins TR; Shou W
J Physiol; 2012 Oct; 590(20):5123-39. PubMed ID: 22826127
[TBL] [Abstract][Full Text] [Related]
35. Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells.
Jehle J; Ficker E; Wan X; Deschenes I; Kisselbach J; Wiedmann F; Staudacher I; Schmidt C; Schweizer PA; Becker R; Katus HA; Thomas D
Br J Pharmacol; 2013 Mar; 168(5):1215-29. PubMed ID: 23061993
[TBL] [Abstract][Full Text] [Related]
36. A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells.
Sala L; Yu Z; Ward-van Oostwaard D; van Veldhoven JP; Moretti A; Laugwitz KL; Mummery CL; IJzerman AP; Bellin M
EMBO Mol Med; 2016 Sep; 8(9):1065-81. PubMed ID: 27470144
[TBL] [Abstract][Full Text] [Related]
37. Human embryonic stem cell derived cardiac myocytes detect hERG-mediated repolarization effects, but not Nav1.5 induced depolarization delay.
Qu Y; Gao B; Fang M; Vargas HM
J Pharmacol Toxicol Methods; 2013; 68(1):74-81. PubMed ID: 23518063
[TBL] [Abstract][Full Text] [Related]
38. Molecular biology and cellular mechanisms of Brugada and long QT syndromes in infants and young children.
Antzelevitch C
J Electrocardiol; 2001; 34 Suppl():177-81. PubMed ID: 11781953
[TBL] [Abstract][Full Text] [Related]
39. Pathogenic mechanism and gene correction for LQTS-causing double mutations in KCNQ1 using a pluripotent stem cell model.
Wang Z; Wang L; Liu W; Hu D; Gao Y; Ge Q; Liu X; Li L; Wang Y; Wang S; Li C
Stem Cell Res; 2019 Jul; 38():101483. PubMed ID: 31226583
[TBL] [Abstract][Full Text] [Related]
40. Characterization of a Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Model for the Study of Variant Pathogenicity: Validation of a
Gélinas R; El Khoury N; Chaix MA; Beauchamp C; Alikashani A; Ethier N; Boucher G; Villeneuve L; Robb L; Latour F; Mondesert B; Rivard L; Goyette P; Talajic M; Fiset C; Rioux JD
Circ Cardiovasc Genet; 2017 Oct; 10(5):. PubMed ID: 29021306
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]