BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 24349440)

  • 1. Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling.
    Peng WC; de Lau W; Madoori PK; Forneris F; Granneman JC; Clevers H; Gros P
    PLoS One; 2013; 8(12):e83110. PubMed ID: 24349440
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The structural basis of R-spondin recognition by LGR5 and RNF43.
    Chen PH; Chen X; Lin Z; Fang D; He X
    Genes Dev; 2013 Jun; 27(12):1345-50. PubMed ID: 23756651
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin.
    Zebisch M; Xu Y; Krastev C; MacDonald BT; Chen M; Gilbert RJ; He X; Jones EY
    Nat Commun; 2013; 4():2787. PubMed ID: 24225776
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.
    Hao HX; Xie Y; Zhang Y; Charlat O; Oster E; Avello M; Lei H; Mickanin C; Liu D; Ruffner H; Mao X; Ma Q; Zamponi R; Bouwmeester T; Finan PM; Kirschner MW; Porter JA; Serluca FC; Cong F
    Nature; 2012 Apr; 485(7397):195-200. PubMed ID: 22575959
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reconstitution of R-spondin:LGR4:ZNRF3 adult stem cell growth factor signaling complexes with recombinant proteins produced in Escherichia coli.
    Moad HE; Pioszak AA
    Biochemistry; 2013 Oct; 52(41):7295-304. PubMed ID: 24050775
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of R-spondin 2 in complex with the ectodomains of its receptors LGR5 and ZNRF3.
    Zebisch M; Jones EY
    J Struct Biol; 2015 Aug; 191(2):149-55. PubMed ID: 26123262
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Engineering high-potency R-spondin adult stem cell growth factors.
    Warner ML; Bell T; Pioszak AA
    Mol Pharmacol; 2015; 87(3):410-20. PubMed ID: 25504990
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin.
    Xie Y; Zamponi R; Charlat O; Ramones M; Swalley S; Jiang X; Rivera D; Tschantz W; Lu B; Quinn L; Dimitri C; Parker J; Jeffery D; Wilcox SK; Watrobka M; LeMotte P; Granda B; Porter JA; Myer VE; Loew A; Cong F
    EMBO Rep; 2013 Dec; 14(12):1120-6. PubMed ID: 24165923
    [TBL] [Abstract][Full Text] [Related]  

  • 9. USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling.
    Giebel N; de Jaime-Soguero A; García Del Arco A; Landry JJM; Tietje M; Villacorta L; Benes V; Fernández-Sáiz V; Acebrón SP
    EMBO Rep; 2021 May; 22(5):e51415. PubMed ID: 33786993
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands.
    Toh Y; Wu L; Park S; Wang A; Tu J; Yu W; Zuo M; Carmon KS; Liu QJ
    Sci Rep; 2023 Jul; 13(1):10796. PubMed ID: 37402772
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dishevelled promotes Wnt receptor degradation through recruitment of ZNRF3/RNF43 E3 ubiquitin ligases.
    Jiang X; Charlat O; Zamponi R; Yang Y; Cong F
    Mol Cell; 2015 May; 58(3):522-33. PubMed ID: 25891077
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.
    Park S; Cui J; Yu W; Wu L; Carmon KS; Liu QJ
    J Biol Chem; 2018 Jun; 293(25):9759-9769. PubMed ID: 29752411
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength.
    de Lau W; Peng WC; Gros P; Clevers H
    Genes Dev; 2014 Feb; 28(4):305-16. PubMed ID: 24532711
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.
    Koo BK; Spit M; Jordens I; Low TY; Stange DE; van de Wetering M; van Es JH; Mohammed S; Heck AJ; Maurice MM; Clevers H
    Nature; 2012 Aug; 488(7413):665-9. PubMed ID: 22895187
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.
    Szenker-Ravi E; Altunoglu U; Leushacke M; Bosso-Lefèvre C; Khatoo M; Thi Tran H; Naert T; Noelanders R; Hajamohideen A; Beneteau C; de Sousa SB; Karaman B; Latypova X; Başaran S; Yücel EB; Tan TT; Vlaminck L; Nayak SS; Shukla A; Girisha KM; Le Caignec C; Soshnikova N; Uyguner ZO; Vleminckx K; Barker N; Kayserili H; Reversade B
    Nature; 2018 May; 557(7706):564-569. PubMed ID: 29769720
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.
    Peng WC; de Lau W; Forneris F; Granneman JC; Huch M; Clevers H; Gros P
    Cell Rep; 2013 Jun; 3(6):1885-92. PubMed ID: 23809763
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway.
    Colozza G; Koo BK
    EMBO Rep; 2021 May; 22(5):e52970. PubMed ID: 33938624
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells.
    Radaszkiewicz T; Bryja V
    Cell Commun Signal; 2020 Jun; 18(1):91. PubMed ID: 32527265
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Non-equivalence of Wnt and R-spondin ligands during Lgr5
    Yan KS; Janda CY; Chang J; Zheng GXY; Larkin KA; Luca VC; Chia LA; Mah AT; Han A; Terry JM; Ootani A; Roelf K; Lee M; Yuan J; Li X; Bolen CR; Wilhelmy J; Davies PS; Ueno H; von Furstenberg RJ; Belgrader P; Ziraldo SB; Ordonez H; Henning SJ; Wong MH; Snyder MP; Weissman IL; Hsueh AJ; Mikkelsen TS; Garcia KC; Kuo CJ
    Nature; 2017 May; 545(7653):238-242. PubMed ID: 28467820
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis for R-spondin recognition by LGR4/5/6 receptors.
    Wang D; Huang B; Zhang S; Yu X; Wu W; Wang X
    Genes Dev; 2013 Jun; 27(12):1339-44. PubMed ID: 23756652
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.