BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 24351823)

  • 1. Cardiac ablation of Rheb1 induces impaired heart growth, endoplasmic reticulum-associated apoptosis and heart failure in infant mice.
    Cao Y; Tao L; Shen S; Xiao J; Wu H; Li B; Wu X; Luo W; Xiao Q; Hu X; Liu H; Nie J; Lu S; Yuan B; Han Z; Xiao B; Yang Z; Li X
    Int J Mol Sci; 2013 Dec; 14(12):24380-98. PubMed ID: 24351823
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia.
    Gao Y; Gao J; Li M; Zheng Y; Wang Y; Zhang H; Wang W; Chu Y; Wang X; Xu M; Cheng T; Ju Z; Yuan W
    J Hematol Oncol; 2016 Apr; 9():36. PubMed ID: 27071307
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rheb1-mTORC1 maintains macrophage differentiation and phagocytosis in mice.
    Wang X; Li M; Gao Y; Gao J; Yang W; Liang H; Ji Q; Li Y; Liu H; Huang J; Cheng T; Yuan W
    Exp Cell Res; 2016 Jun; 344(2):219-28. PubMed ID: 27163399
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic and pharmacological inhibition of Rheb1-mTORC1 signaling exerts cardioprotection against adverse cardiac remodeling in mice.
    Wu X; Cao Y; Nie J; Liu H; Lu S; Hu X; Zhu J; Zhao X; Chen J; Chen X; Yang Z; Li X
    Am J Pathol; 2013 Jun; 182(6):2005-14. PubMed ID: 23567640
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rheb1 is required for mTORC1 and myelination in postnatal brain development.
    Zou J; Zhou L; Du XX; Ji Y; Xu J; Tian J; Jiang W; Zou Y; Yu S; Gan L; Luo M; Yang Q; Cui Y; Yang W; Xia X; Chen M; Zhao X; Shen Y; Chen PY; Worley PF; Xiao B
    Dev Cell; 2011 Jan; 20(1):97-108. PubMed ID: 21238928
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic deletion of Rheb1 in the brain reduces food intake and causes hypoglycemia with altered peripheral metabolism.
    Yang W; Jiang W; Luo L; Bu J; Pang D; Wei J; Du C; Xia X; Cui Y; Liu S; Mao Q; Chen M
    Int J Mol Sci; 2014 Jan; 15(1):1499-510. PubMed ID: 24451134
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period.
    Tamai T; Yamaguchi O; Hikoso S; Takeda T; Taneike M; Oka T; Oyabu J; Murakawa T; Nakayama H; Uno Y; Horie K; Nishida K; Sonenberg N; Shah AM; Takeda J; Komuro I; Otsu K
    J Biol Chem; 2013 Apr; 288(14):10176-10187. PubMed ID: 23426372
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Downregulation of Glutamate Transporter EAAT4 by Conditional Knockout of Rheb1 in Cerebellar Purkinje Cells.
    Jiang NW; Wang DJ; Xie YJ; Zhou L; Su LD; Li H; Wang QW; Shen Y
    Cerebellum; 2016 Jun; 15(3):314-21. PubMed ID: 26194056
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure.
    Xu N; Guan S; Chen Z; Yu Y; Xie J; Pan FY; Zhao NW; Liu L; Yang ZZ; Gao X; Xu B; Li CJ
    J Pathol; 2015 Apr; 235(5):672-85. PubMed ID: 25385233
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BMI1 promotes cardiac fibrosis in ischemia-induced heart failure via the PTEN-PI3K/Akt-mTOR signaling pathway.
    Yang W; Wu Z; Yang K; Han Y; Chen Y; Zhao W; Huang F; Jin Y; Jin W
    Am J Physiol Heart Circ Physiol; 2019 Jan; 316(1):H61-H69. PubMed ID: 30359076
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice.
    Babaev VR; Yeung M; Erbay E; Ding L; Zhang Y; May JM; Fazio S; Hotamisligil GS; Linton MF
    Arterioscler Thromb Vasc Biol; 2016 Jun; 36(6):1122-31. PubMed ID: 27102962
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome.
    Sciarretta S; Zhai P; Shao D; Maejima Y; Robbins J; Volpe M; Condorelli G; Sadoshima J
    Circulation; 2012 Mar; 125(9):1134-46. PubMed ID: 22294621
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen.
    Satoh M; Matter CM; Ogita H; Takeshita K; Wang CY; Dorn GW; Liao JK
    Circulation; 2007 Jun; 115(25):3197-204. PubMed ID: 17562954
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RHEB1 expression in embryonic and postnatal mouse.
    Tian Q; Smart JL; Clement JH; Wang Y; Derkatch A; Schubert H; Danilchik MV; Marks DL; Fedorov LM
    Histochem Cell Biol; 2016 May; 145(5):561-72. PubMed ID: 26708151
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis.
    Kang YJ; Lu MK; Guan KL
    Cell Death Differ; 2011 Jan; 18(1):133-44. PubMed ID: 20616807
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumorigenic activity and therapeutic inhibition of Rheb GTPase.
    Mavrakis KJ; Zhu H; Silva RL; Mills JR; Teruya-Feldstein J; Lowe SW; Tam W; Pelletier J; Wendel HG
    Genes Dev; 2008 Aug; 22(16):2178-88. PubMed ID: 18708578
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling.
    Hanker AB; Mitin N; Wilder RS; Henske EP; Tamanoi F; Cox AD; Der CJ
    Oncogene; 2010 Jan; 29(3):380-91. PubMed ID: 19838215
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain.
    Zou Y; Jiang W; Wang J; Li Z; Zhang J; Bu J; Zou J; Zhou L; Yu S; Cui Y; Yang W; Luo L; Lu QR; Liu Y; Chen M; Worley PF; Xiao B
    J Neurosci; 2014 Nov; 34(47):15764-78. PubMed ID: 25411504
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alpha1-adrenergic receptors activate AKT via a Pyk2/PDK-1 pathway that is tonically inhibited by novel protein kinase C isoforms in cardiomyocytes.
    Guo J; Sabri A; Elouardighi H; Rybin V; Steinberg SF
    Circ Res; 2006 Dec; 99(12):1367-75. PubMed ID: 17110596
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Long Noncoding RNA FTX Reduces Hypertrophy of Neonatal Mouse Cardiac Myocytes and Regulates the PTEN/PI3K/Akt Signaling Pathway by Sponging MicroRNA-22.
    Yang X; Tao L; Zhu J; Zhang S
    Med Sci Monit; 2019 Dec; 25():9609-9617. PubMed ID: 31840653
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.