BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

529 related articles for article (PubMed ID: 24355923)

  • 1. Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis.
    Gallo EM; Loch DC; Habashi JP; Calderon JF; Chen Y; Bedja D; van Erp C; Gerber EE; Parker SJ; Sauls K; Judge DP; Cooke SK; Lindsay ME; Rouf R; Myers L; ap Rhys CM; Kent KC; Norris RA; Huso DL; Dietz HC
    J Clin Invest; 2014 Jan; 124(1):448-60. PubMed ID: 24355923
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dysregulated TGF-β signaling alters bone microstructure in a mouse model of Loeys-Dietz syndrome.
    Dewan AK; Tomlinson RE; Mitchell S; Goh BC; Yung RM; Kumar S; Tan EW; Faugere MC; Dietz HC; Clemens TL; Sponseller PD
    J Orthop Res; 2015 Oct; 33(10):1447-54. PubMed ID: 26173585
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aortic aneurysms in Loeys-Dietz syndrome - a tale of two pathways?
    Davis F; Rateri DL; Daugherty A
    J Clin Invest; 2014 Jan; 124(1):79-81. PubMed ID: 24355917
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional validation reveals the novel missense V419L variant in
    Cousin MA; Zimmermann MT; Mathison AJ; Blackburn PR; Boczek NJ; Oliver GR; Lomberk GA; Urrutia RA; Deyle DR; Klee EW
    Cold Spring Harb Mol Case Stud; 2017 Jul; 3(4):. PubMed ID: 28679693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lineage-specific events underlie aortic root aneurysm pathogenesis in Loeys-Dietz syndrome.
    MacFarlane EG; Parker SJ; Shin JY; Kang BE; Ziegler SG; Creamer TJ; Bagirzadeh R; Bedja D; Chen Y; Calderon JF; Weissler K; Frischmeyer-Guerrerio PA; Lindsay ME; Habashi JP; Dietz HC
    J Clin Invest; 2019 Feb; 129(2):659-675. PubMed ID: 30614814
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loeys-Dietz syndrome type I and type II: clinical findings and novel mutations in two Italian patients.
    Drera B; Ritelli M; Zoppi N; Wischmeijer A; Gnoli M; Fattori R; Calzavara-Pinton PG; Barlati S; Colombi M
    Orphanet J Rare Dis; 2009 Nov; 4():24. PubMed ID: 19883511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of Gremlin-1 in patients with Loeys-Dietz syndrome: implications on pathophysiology and early disease detection.
    Wellbrock J; Sheikhzadeh S; Oliveira-Ferrer L; Stamm H; Hillebrand M; Keyser B; Klokow M; Vohwinkel G; Bonk V; Otto B; Streichert T; Balabanov S; Hagel C; Rybczynski M; Bentzien F; Bokemeyer C; von Kodolitsch Y; Fiedler W
    PLoS One; 2014; 9(8):e104742. PubMed ID: 25116393
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteomics reveals Rictor as a noncanonical TGF-β signaling target during aneurysm progression in Marfan mice.
    Parker SJ; Stotland A; MacFarlane E; Wilson N; Orosco A; Venkatraman V; Madrid K; Gottlieb R; Dietz HC; Van Eyk JE
    Am J Physiol Heart Circ Physiol; 2018 Nov; 315(5):H1112-H1126. PubMed ID: 30004239
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Duplication of the TGFBR1 gene causes features of Loeys-Dietz syndrome.
    Breckpot J; Budts W; De Zegher F; Vermeesch JR; Devriendt K
    Eur J Med Genet; 2010; 53(6):408-10. PubMed ID: 20813212
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pathophysiology and Management of Cardiovascular Manifestations in Marfan and Loeys-Dietz Syndromes.
    Takeda N; Yagi H; Hara H; Fujiwara T; Fujita D; Nawata K; Inuzuka R; Taniguchi Y; Harada M; Toko H; Akazawa H; Komuro I
    Int Heart J; 2016 May; 57(3):271-7. PubMed ID: 27181042
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TGF-β Signaling-Related Genes and Thoracic Aortic Aneurysms and Dissections.
    Takeda N; Hara H; Fujiwara T; Kanaya T; Maemura S; Komuro I
    Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30037098
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impaired vascular contractility and aortic wall degeneration in fibulin-4 deficient mice: effect of angiotensin II type 1 (AT1) receptor blockade.
    Moltzer E; te Riet L; Swagemakers SM; van Heijningen PM; Vermeij M; van Veghel R; Bouhuizen AM; van Esch JH; Lankhorst S; Ramnath NW; de Waard MC; Duncker DJ; van der Spek PJ; Rouwet EV; Danser AH; Essers J
    PLoS One; 2011; 6(8):e23411. PubMed ID: 21858106
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aneurysm syndromes caused by mutations in the TGF-beta receptor.
    Loeys BL; Schwarze U; Holm T; Callewaert BL; Thomas GH; Pannu H; De Backer JF; Oswald GL; Symoens S; Manouvrier S; Roberts AE; Faravelli F; Greco MA; Pyeritz RE; Milewicz DM; Coucke PJ; Cameron DE; Braverman AC; Byers PH; De Paepe AM; Dietz HC
    N Engl J Med; 2006 Aug; 355(8):788-98. PubMed ID: 16928994
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms.
    Angelov SN; Hu JH; Wei H; Airhart N; Shi M; Dichek DA
    Arterioscler Thromb Vasc Biol; 2017 Nov; 37(11):2102-2113. PubMed ID: 28729364
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events.
    Yang P; Schmit BM; Fu C; DeSart K; Oh SP; Berceli SA; Jiang Z
    Sci Rep; 2016 Oct; 6():35444. PubMed ID: 27739498
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TGFBR1 mutations associated with Loeys-Dietz syndrome are inactivating.
    Cardoso S; Robertson SP; Daniel PB
    J Recept Signal Transduct Res; 2012 Jun; 32(3):150-5. PubMed ID: 22414221
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A new sporadic case of early-onset Loeys-Dietz syndrome due to the recurrent mutation p.R528C in the TGFBR2 gene substantiates interindividual clinical variability.
    Jamsheer A; Henggeler C; Wierzba J; Loeys B; De Paepe A; Stheneur Ch; Badziag N; Matuszewska K; Matyas G; Latos-Bielenska A
    J Appl Genet; 2009; 50(4):405-10. PubMed ID: 19875893
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling.
    Gong K; Xing D; Li P; Aksut B; Ambalavanan N; Yang Q; Nozell SE; Oparil S; Chen YF
    Am J Physiol Lung Cell Mol Physiol; 2011 Dec; 301(6):L899-907. PubMed ID: 21926264
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glucocorticoids recruit Tgfbr3 and Smad1 to shift transforming growth factor-β signaling from the Tgfbr1/Smad2/3 axis to the Acvrl1/Smad1 axis in lung fibroblasts.
    Schwartze JT; Becker S; Sakkas E; Wujak ŁA; Niess G; Usemann J; Reichenberger F; Herold S; Vadász I; Mayer K; Seeger W; Morty RE
    J Biol Chem; 2014 Feb; 289(6):3262-75. PubMed ID: 24347165
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 27.