305 related articles for article (PubMed ID: 24367103)
1. AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation.
Lu H; Li Z; Xue Y; Schulze-Gahmen U; Johnson JR; Krogan NJ; Alber T; Zhou Q
Proc Natl Acad Sci U S A; 2014 Jan; 111(1):E15-24. PubMed ID: 24367103
[TBL] [Abstract][Full Text] [Related]
2. Disrupting the Cdk9/Cyclin T1 heterodimer of 7SK snRNP for the Brd4 and AFF1/4 guided reconstitution of active P-TEFb.
Zhou K; Zhuang S; Liu F; Chen Y; Li Y; Wang S; Li Y; Wen H; Lin X; Wang J; Huang Y; He C; Xu N; Li Z; Xu L; Zhang Z; Chen LF; Chen R; Liu M
Nucleic Acids Res; 2022 Jan; 50(2):750-762. PubMed ID: 34935961
[TBL] [Abstract][Full Text] [Related]
3. HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.
Sobhian B; Laguette N; Yatim A; Nakamura M; Levy Y; Kiernan R; Benkirane M
Mol Cell; 2010 May; 38(3):439-51. PubMed ID: 20471949
[TBL] [Abstract][Full Text] [Related]
4. Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4.
Gu J; Babayeva ND; Suwa Y; Baranovskiy AG; Price DH; Tahirov TH
Cell Cycle; 2014; 13(11):1788-97. PubMed ID: 24727379
[TBL] [Abstract][Full Text] [Related]
5. Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes.
Mbonye UR; Gokulrangan G; Datt M; Dobrowolski C; Cooper M; Chance MR; Karn J
PLoS Pathog; 2013; 9(5):e1003338. PubMed ID: 23658523
[TBL] [Abstract][Full Text] [Related]
6. Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.
Liu P; Xiang Y; Fujinaga K; Bartholomeeusen K; Nilson KA; Price DH; Peterlin BM
J Biol Chem; 2014 Apr; 289(14):9918-25. PubMed ID: 24515107
[TBL] [Abstract][Full Text] [Related]
7. Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation.
Mbonye U; Wang B; Gokulrangan G; Shi W; Yang S; Karn J
J Biol Chem; 2018 Jun; 293(26):10009-10025. PubMed ID: 29743242
[TBL] [Abstract][Full Text] [Related]
8. The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK.
Krueger BJ; Varzavand K; Cooper JJ; Price DH
PLoS One; 2010 Aug; 5(8):e12335. PubMed ID: 20808803
[TBL] [Abstract][Full Text] [Related]
9. Super elongation complex promotes early HIV transcription and its function is modulated by P-TEFb.
Kuzmina A; Krasnopolsky S; Taube R
Transcription; 2017 May; 8(3):133-149. PubMed ID: 28340332
[TBL] [Abstract][Full Text] [Related]
10. CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA.
Garber ME; Mayall TP; Suess EM; Meisenhelder J; Thompson NE; Jones KA
Mol Cell Biol; 2000 Sep; 20(18):6958-69. PubMed ID: 10958691
[TBL] [Abstract][Full Text] [Related]
11. A single point mutation in cyclin T1 eliminates binding to Hexim1, Cdk9 and RNA but not to AFF4 and enforces repression of HIV transcription.
Kuzmina A; Verstraete N; Galker S; Maatook M; Bensaude O; Taube R
Retrovirology; 2014 Jul; 11():51. PubMed ID: 24985467
[TBL] [Abstract][Full Text] [Related]
12. Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription.
Barboric M; Yik JH; Czudnochowski N; Yang Z; Chen R; Contreras X; Geyer M; Matija Peterlin B; Zhou Q
Nucleic Acids Res; 2007; 35(6):2003-12. PubMed ID: 17341462
[TBL] [Abstract][Full Text] [Related]
13. The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.
Faust TB; Li Y; Bacon CW; Jang GM; Weiss A; Jayaraman B; Newton BW; Krogan NJ; D'Orso I; Frankel AD
Elife; 2018 May; 7():. PubMed ID: 29845934
[TBL] [Abstract][Full Text] [Related]
14. Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription.
Lu H; Li Z; Zhang W; Schulze-Gahmen U; Xue Y; Zhou Q
Nucleic Acids Res; 2015 Jul; 43(12):5868-79. PubMed ID: 26007649
[TBL] [Abstract][Full Text] [Related]
15. Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein.
Bartholomeeusen K; Xiang Y; Fujinaga K; Peterlin BM
J Biol Chem; 2012 Oct; 287(43):36609-16. PubMed ID: 22952229
[TBL] [Abstract][Full Text] [Related]
16. MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner.
Michels AA; Nguyen VT; Fraldi A; Labas V; Edwards M; Bonnet F; Lania L; Bensaude O
Mol Cell Biol; 2003 Jul; 23(14):4859-69. PubMed ID: 12832472
[TBL] [Abstract][Full Text] [Related]
17. The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat.
Schulze-Gahmen U; Upton H; Birnberg A; Bao K; Chou S; Krogan NJ; Zhou Q; Alber T
Elife; 2013 Mar; 2():e00327. PubMed ID: 23471103
[TBL] [Abstract][Full Text] [Related]
18. Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.
Schröder S; Cho S; Zeng L; Zhang Q; Kaehlcke K; Mak L; Lau J; Bisgrove D; Schnölzer M; Verdin E; Zhou MM; Ott M
J Biol Chem; 2012 Jan; 287(2):1090-9. PubMed ID: 22084242
[TBL] [Abstract][Full Text] [Related]
19. Human T-lymphotropic virus type 1 Tax protein complexes with P-TEFb and competes for Brd4 and 7SK snRNP/HEXIM1 binding.
Cho WK; Jang MK; Huang K; Pise-Masison CA; Brady JN
J Virol; 2010 Dec; 84(24):12801-9. PubMed ID: 20926576
[TBL] [Abstract][Full Text] [Related]
20. Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA.
D'Orso I; Jang GM; Pastuszak AW; Faust TB; Quezada E; Booth DS; Frankel AD
Mol Cell Biol; 2012 Dec; 32(23):4780-93. PubMed ID: 23007159
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]