BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 24368541)

  • 1. A loss-of-function mutation in PTCH1 suggests a role for autocrine hedgehog signaling in colorectal tumorigenesis.
    Chung JH; Bunz F
    Oncotarget; 2013 Dec; 4(12):2208-11. PubMed ID: 24368541
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL.
    Decker S; Zirlik K; Djebatchie L; Hartmann D; Ihorst G; Schmitt-Graeff A; Herchenbach D; Jumaa H; Warmuth M; Veelken H; Dierks C
    Blood; 2012 Jan; 119(4):997-1007. PubMed ID: 22130798
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hedgehog signaling pathway is inactive in colorectal cancer cell lines.
    Chatel G; Ganeff C; Boussif N; Delacroix L; Briquet A; Nolens G; Winkler R
    Int J Cancer; 2007 Dec; 121(12):2622-7. PubMed ID: 17683069
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aberrant methylation of the PTCH1 gene promoter region in aberrant crypt foci.
    Peng L; Hu J; Li S; Wang Z; Xia B; Jiang B; Li B; Zhang Y; Wang J; Wang X
    Int J Cancer; 2013 Jan; 132(2):E18-25. PubMed ID: 22945423
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site.
    Agren M; Kogerman P; Kleman MI; Wessling M; Toftgård R
    Gene; 2004 Apr; 330():101-14. PubMed ID: 15087129
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting the hedgehog signaling pathway with interacting peptides to Patched-1.
    Nakamura M; Tanaka H; Nagayoshi Y; Nakashima H; Tsutsumi K; Ohtsuka T; Takahata S; Tanaka M; Okada H
    J Gastroenterol; 2012 Apr; 47(4):452-60. PubMed ID: 22170414
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.
    Holtz AM; Peterson KA; Nishi Y; Morin S; Song JY; Charron F; McMahon AP; Allen BL
    Development; 2013 Aug; 140(16):3423-34. PubMed ID: 23900540
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors.
    Lee SJ; Do IG; Lee J; Kim KM; Jang J; Sohn I; Kang WK
    Target Oncol; 2013 Dec; 8(4):271-80. PubMed ID: 23371028
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS
    J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct effects of the mesenchymal dysplasia gene variant of murine Patched-1 protein on canonical and non-canonical Hedgehog signaling pathways.
    Harvey MC; Fleet A; Okolowsky N; Hamel PA
    J Biol Chem; 2014 Apr; 289(15):10939-10949. PubMed ID: 24570001
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LKB1 inhibits breast cancer partially through repressing the Hedgehog signaling pathway.
    Zhuang Z; Wang K; Cheng X; Qu X; Jiang B; Li Z; Luo J; Shao Z; Duan T
    PLoS One; 2013; 8(7):e67431. PubMed ID: 23861764
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Adenovirus vector-mediated Gli1 siRNA induces growth inhibition and apoptosis in human pancreatic cancer with Smo-dependent or Smo-independent Hh pathway activation in vitro and in vivo.
    Guo J; Gao J; Li Z; Gong Y; Man X; Jin J; Wu H
    Cancer Lett; 2013 Oct; 339(2):185-94. PubMed ID: 23791879
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures.
    Cohen JR; Resnick DZ; Niewiadomski P; Dong H; Liau LM; Waschek JA
    BMC Cancer; 2010 Dec; 10():676. PubMed ID: 21143927
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased expression of the hedgehog signaling pathway in pediatric solid malignancies.
    Oue T; Yoneda A; Uehara S; Yamanaka H; Fukuzawa M
    J Pediatr Surg; 2010 Feb; 45(2):387-92. PubMed ID: 20152358
    [TBL] [Abstract][Full Text] [Related]  

  • 15. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched.
    Busch AM; Galimberti F; Nehls KE; Roengvoraphoj M; Sekula D; Li B; Guo Y; Direnzo J; Fiering SN; Spinella MJ; Robbins DJ; Memoli VA; Freemantle SJ; Dmitrovsky E
    Cancer Biol Ther; 2014 Apr; 15(4):463-72. PubMed ID: 24496080
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hedgehog Signaling in Colorectal Cancer: All in the Stroma?
    Geyer N; Gerling M
    Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33498528
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The hedgehog-patched signaling pathway and function in the mammalian ovary: a novel role for hedgehog proteins in stimulating proliferation and steroidogenesis of theca cells.
    Spicer LJ; Sudo S; Aad PY; Wang LS; Chun SY; Ben-Shlomo I; Klein C; Hsueh AJ
    Reproduction; 2009 Aug; 138(2):329-39. PubMed ID: 19433502
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hedgehog signalling: emerging evidence for non-canonical pathways.
    Jenkins D
    Cell Signal; 2009 Jul; 21(7):1023-34. PubMed ID: 19399989
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas.
    Bian YH; Huang SH; Yang L; Ma XL; Xie JW; Zhang HW
    World J Gastroenterol; 2007 Mar; 13(11):1659-65. PubMed ID: 17461467
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression, Purification, and Structure Determination of Human PTCH1-HH-N Complexes.
    Qi X; Schmiege P; Esparza L; Li X
    Methods Mol Biol; 2022; 2374():107-120. PubMed ID: 34562247
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.