BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 24369116)

  • 1. Comparative structural and conformational studies on H43R and W32F mutants of copper-zinc superoxide dismutase by molecular dynamics simulation.
    Muneeswaran G; Kartheeswaran S; Muthukumar K; Dharmaraj CD; Karunakaran C
    Biophys Chem; 2014 Jan; 185():70-8. PubMed ID: 24369116
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu-Zn superoxide dismutase.
    Strange RW; Yong CW; Smith W; Hasnain SS
    Proc Natl Acad Sci U S A; 2007 Jun; 104(24):10040-4. PubMed ID: 17548825
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization.
    DiDonato M; Craig L; Huff ME; Thayer MM; Cardoso RM; Kassmann CJ; Lo TP; Bruns CK; Powers ET; Kelly JW; Getzoff ED; Tainer JA
    J Mol Biol; 2003 Sep; 332(3):601-15. PubMed ID: 12963370
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Common dynamical signatures of familial amyotrophic lateral sclerosis-associated structurally diverse Cu, Zn superoxide dismutase mutants.
    Khare SD; Dokholyan NV
    Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3147-52. PubMed ID: 16488975
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural instability and Cu-dependent pro-oxidant activity acquired by the apo form of mutant SOD1 associated with amyotrophic lateral sclerosis.
    Kitamura F; Fujimaki N; Okita W; Hiramatsu H; Takeuchi H
    Biochemistry; 2011 May; 50(20):4242-50. PubMed ID: 21506602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unveiling the unfolding pathway of FALS associated G37R SOD1 mutant: a computational study.
    Milardi D; Pappalardo M; Grasso DM; La Rosa C
    Mol Biosyst; 2010 Jun; 6(6):1032-9. PubMed ID: 20485746
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Denaturational stress induces formation of zinc-deficient monomers of Cu,Zn superoxide dismutase: implications for pathogenesis in amyotrophic lateral sclerosis.
    Mulligan VK; Kerman A; Ho S; Chakrabartty A
    J Mol Biol; 2008 Nov; 383(2):424-36. PubMed ID: 18761352
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation.
    Ray SS; Nowak RJ; Brown RH; Lansbury PT
    Proc Natl Acad Sci U S A; 2005 Mar; 102(10):3639-44. PubMed ID: 15738401
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis.
    Valentine JS; Doucette PA; Zittin Potter S
    Annu Rev Biochem; 2005; 74():563-93. PubMed ID: 15952898
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V.
    Schmidlin T; Kennedy BK; Daggett V
    Biophys J; 2009 Sep; 97(6):1709-18. PubMed ID: 19751676
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation.
    Chattopadhyay M; Nwadibia E; Strong CD; Gralla EB; Valentine JS; Whitelegge JP
    J Biol Chem; 2015 Dec; 290(51):30624-36. PubMed ID: 26511321
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis.
    Ray SS; Nowak RJ; Strokovich K; Brown RH; Walz T; Lansbury PT
    Biochemistry; 2004 May; 43(17):4899-905. PubMed ID: 15109247
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism for transforming cytosolic SOD1 into integral membrane proteins of organelles by ALS-causing mutations.
    Lim L; Lee X; Song J
    Biochim Biophys Acta; 2015 Jan; 1848(1 Pt A):1-7. PubMed ID: 25306968
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A common property of amyotrophic lateral sclerosis-associated variants: destabilization of the copper/zinc superoxide dismutase electrostatic loop.
    Molnar KS; Karabacak NM; Johnson JL; Wang Q; Tiwari A; Hayward LJ; Coales SJ; Hamuro Y; Agar JN
    J Biol Chem; 2009 Nov; 284(45):30965-73. PubMed ID: 19635794
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FALS mutations in Cu, Zn superoxide dismutase destabilize the dimer and increase dimer dissociation propensity: a large-scale thermodynamic analysis.
    Khare SD; Caplow M; Dokholyan NV
    Amyloid; 2006 Dec; 13(4):226-35. PubMed ID: 17107883
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intracellular conformational alterations of mutant SOD1 and the implications for fALS-associated SOD1 mutant induced motor neuron cell death.
    Zhang F; Zhu H
    Biochim Biophys Acta; 2006 Mar; 1760(3):404-14. PubMed ID: 16431026
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amyotrophic lateral sclerosis disease-related mutations disrupt the dimerization of superoxide dismutase 1 - A comparative molecular dynamics simulation study.
    Basith S; Manavalan B; Lee G
    Comput Biol Med; 2022 Dec; 151(Pt B):106319. PubMed ID: 36446187
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pro-oxidant copper-binding mode of the Apo form of ALS-linked SOD1 mutant H43R denatured at physiological temperature.
    Fujimaki N; Kitamura F; Takeuchi H
    Biochemistry; 2013 Aug; 52(31):5184-94. PubMed ID: 23837654
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metalation of the amyotrophic lateral sclerosis mutant glycine 37 to arginine superoxide dismutase (SOD1) apoprotein restores its structural and dynamical properties in solution to those of metalated wild-type SOD1.
    Banci L; Bertini I; D'Amelio N; Libralesso E; Turano P; Valentine JS
    Biochemistry; 2007 Sep; 46(35):9953-62. PubMed ID: 17683122
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS.
    Banci L; Bertini I; Durazo A; Girotto S; Gralla EB; Martinelli M; Valentine JS; Vieru M; Whitelegge JP
    Proc Natl Acad Sci U S A; 2007 Jul; 104(27):11263-7. PubMed ID: 17592131
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.