BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 24369116)

  • 41. The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis.
    Strange RW; Antonyuk S; Hough MA; Doucette PA; Rodriguez JA; Hart PJ; Hayward LJ; Valentine JS; Hasnain SS
    J Mol Biol; 2003 May; 328(4):877-91. PubMed ID: 12729761
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Local destabilization of the metal-binding region in human copper-zinc superoxide dismutase by remote mutations is a possible determinant for progression of ALS.
    Hennig J; Andrésen C; Museth AK; Lundström P; Tibell LA; Jonsson BH
    Biochemistry; 2015 Jan; 54(2):323-33. PubMed ID: 25496420
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Zinc and copper in the pathogenesis of amyotrophic lateral sclerosis.
    Elliott JL
    Prog Neuropsychopharmacol Biol Psychiatry; 2001 Aug; 25(6):1169-85. PubMed ID: 11474839
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes.
    Pratt AJ; Shin DS; Merz GE; Rambo RP; Lancaster WA; Dyer KN; Borbat PP; Poole FL; Adams MW; Freed JH; Crane BR; Tainer JA; Getzoff ED
    Proc Natl Acad Sci U S A; 2014 Oct; 111(43):E4568-76. PubMed ID: 25316790
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregation.
    Ding F; Dokholyan NV
    Proc Natl Acad Sci U S A; 2008 Dec; 105(50):19696-701. PubMed ID: 19052230
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Mutations in Superoxide Dismutase 1 (Sod1) Linked to Familial Amyotrophic Lateral Sclerosis Can Disrupt High-Affinity Zinc-Binding Promoted by the Copper Chaperone for Sod1 (Ccs).
    Boyd SD; Ullrich MS; Calvo JS; Behnia F; Meloni G; Winkler DD
    Molecules; 2020 Feb; 25(5):. PubMed ID: 32121118
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Parsing disease-relevant protein modifications from epiphenomena: perspective on the structural basis of SOD1-mediated ALS.
    Schmitt ND; Agar JN
    J Mass Spectrom; 2017 Jul; 52(7):480-491. PubMed ID: 28558143
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Structural and functional analysis of human SOD1 in amyotrophic lateral sclerosis.
    Moreira LG; Pereira LC; Drummond PR; De Mesquita JF
    PLoS One; 2013; 8(12):e81979. PubMed ID: 24312616
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Crystal structure of the second domain of the human copper chaperone for superoxide dismutase.
    Lamb AL; Wernimont AK; Pufahl RA; O'Halloran TV; Rosenzweig AC
    Biochemistry; 2000 Feb; 39(7):1589-95. PubMed ID: 10677207
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Structural discovery of small molecule binding sites in Cu-Zn human superoxide dismutase familial amyotrophic lateral sclerosis mutants provides insights for lead optimization.
    Antonyuk S; Strange RW; Hasnain SS
    J Med Chem; 2010 Feb; 53(3):1402-6. PubMed ID: 20067275
    [TBL] [Abstract][Full Text] [Related]  

  • 51. In-cell NMR reveals potential precursor of toxic species from SOD1 fALS mutants.
    Luchinat E; Barbieri L; Rubino JT; Kozyreva T; Cantini F; Banci L
    Nat Commun; 2014 Nov; 5():5502. PubMed ID: 25429517
    [TBL] [Abstract][Full Text] [Related]  

  • 52. ALS-causing SOD1 mutations promote production of copper-deficient misfolded species.
    Ip P; Mulligan VK; Chakrabartty A
    J Mol Biol; 2011 Jun; 409(5):839-52. PubMed ID: 21549128
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Early steps in thermal unfolding of superoxide dismutase 1 are similar to the conformational changes associated with the ALS-associated A4V mutation.
    Schmidlin T; Ploeger K; Jonsson AL; Daggett V
    Protein Eng Des Sel; 2013 Aug; 26(8):503-13. PubMed ID: 23784844
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Mutant SOD1 instability: implications for toxicity in amyotrophic lateral sclerosis.
    Tiwari A; Hayward LJ
    Neurodegener Dis; 2005; 2(3-4):115-27. PubMed ID: 16909016
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Many roads lead to Rome? Multiple modes of Cu,Zn superoxide dismutase destabilization, misfolding and aggregation in amyotrophic lateral sclerosis.
    Broom HR; Rumfeldt JA; Meiering EM
    Essays Biochem; 2014; 56():149-65. PubMed ID: 25131593
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells.
    Oh YK; Shin KS; Yuan J; Kang SJ
    J Neurochem; 2008 Feb; 104(4):993-1005. PubMed ID: 18233996
    [TBL] [Abstract][Full Text] [Related]  

  • 58. [SOD1 gene mutations in patients with amyotrophic lateral sclerosis: potential for the method of molecular].
    Lysogorskaia EV; Rossokhin AV; Abramycheva NIu; Zakharova MN; Illarioshkin SN
    Mol Biol (Mosk); 2013; 47(5):861-7. PubMed ID: 25509359
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Voltage-Induced Misfolding of Zinc-Replete ALS Mutant Superoxide Dismutase-1.
    Shi Y; Acerson MJ; Shuford KL; Shaw BF
    ACS Chem Neurosci; 2015 Oct; 6(10):1696-707. PubMed ID: 26207449
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Computational studies of the metal-binding site of the wild-type and the H46R mutant of the copper, zinc superoxide dismutase.
    Mera-Adasme R; Mendizábal F; Gonzalez M; Miranda-Rojas S; Olea-Azar C; Sundholm D
    Inorg Chem; 2012 May; 51(10):5561-8. PubMed ID: 22545761
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.