174 related articles for article (PubMed ID: 24374199)
21. Cytochrome P450 2D (CYP2D) enzyme dysfunction associated with aging and serotonin deficiency in the brain and liver of female Dark Agouti rats.
Haduch A; Danek PJ; Kuban W; Pukło R; Alenina N; Gołębiowska J; Popik P; Bader M; Daniel WA
Neurochem Int; 2022 Jan; 152():105223. PubMed ID: 34780807
[TBL] [Abstract][Full Text] [Related]
22. Human CYP2D6 and mouse CYP2Ds: organ distribution in a humanized mouse model.
Miksys SL; Cheung C; Gonzalez FJ; Tyndale RF
Drug Metab Dispos; 2005 Oct; 33(10):1495-502. PubMed ID: 16033950
[TBL] [Abstract][Full Text] [Related]
23. Decreased hepatic drug metabolising enzyme activity in rats with nitrosamine-induced tumours.
Maliakal PP; Coville PF; Wanwimolruk S
Drug Metabol Drug Interact; 2002; 19(1):13-27. PubMed ID: 12222751
[TBL] [Abstract][Full Text] [Related]
24. Determinants of the substrate specificity of human cytochrome P-450 CYP2D6: design and construction of a mutant with testosterone hydroxylase activity.
Smith G; Modi S; Pillai I; Lian LY; Sutcliffe MJ; Pritchard MP; Friedberg T; Roberts GC; Wolf CR
Biochem J; 1998 May; 331 ( Pt 3)(Pt 3):783-92. PubMed ID: 9560305
[TBL] [Abstract][Full Text] [Related]
25. Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment.
Mann A; Miksys S; Lee A; Mash DC; Tyndale RF
Neuropharmacology; 2008 Dec; 55(7):1147-55. PubMed ID: 18687346
[TBL] [Abstract][Full Text] [Related]
26. Predicting drug metabolism by cytochrome P450 2C9: comparison with the 2D6 and 3A4 isoforms.
Rydberg P; Olsen L
ChemMedChem; 2012 Jul; 7(7):1202-9. PubMed ID: 22593031
[TBL] [Abstract][Full Text] [Related]
27. Human CYP2D6 Is Functional in Brain In Vivo: Evidence from Humanized CYP2D6 Transgenic Mice.
Tolledo C; Stocco MR; Miksys S; Gonzalez FJ; Tyndale RF
Mol Neurobiol; 2020 Jun; 57(6):2509-2520. PubMed ID: 32189192
[TBL] [Abstract][Full Text] [Related]
28. Chronic treatment with asenapine affects cytochrome P450 2D (CYP2D) in rat brain and liver. Pharmacological aspects.
Danek PJ; Bromek E; Haduch A; Daniel WA
Neurochem Int; 2021 Dec; 151():105209. PubMed ID: 34666077
[TBL] [Abstract][Full Text] [Related]
29. Stress is a critical player in CYP3A, CYP2C, and CYP2D regulation: role of adrenergic receptor signaling pathways.
Daskalopoulos EP; Malliou F; Rentesi G; Marselos M; Lang MA; Konstandi M
Am J Physiol Endocrinol Metab; 2012 Jul; 303(1):E40-54. PubMed ID: 22510709
[TBL] [Abstract][Full Text] [Related]
30. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
[TBL] [Abstract][Full Text] [Related]
31. CYP2D in the brain.
Funae Y; Kishimoto W; Cho T; Niwa T; Hiroi T
Drug Metab Pharmacokinet; 2003; 18(6):337-49. PubMed ID: 15618754
[TBL] [Abstract][Full Text] [Related]
32. Pharmacokinetic interaction between tamoxifen and ondansetron in rats: non-competitive (hepatic) and competitive (intestinal) inhibition of tamoxifen metabolism by ondansetron via CYP2D subfamily and 3A1/2.
Yang SH; Suh JH; Lee MG
Cancer Chemother Pharmacol; 2010 Feb; 65(3):407-18. PubMed ID: 19504095
[TBL] [Abstract][Full Text] [Related]
33. Stereoselective differences in the cytochrome P450-dependent dealkylation and demethylenation of N-methyl-benzodioxolyl-butanamine (MBDB, Eden) enantiomers.
Meyer MR; Peters FT; Maurer HH
Biochem Pharmacol; 2009 Jun; 77(11):1725-34. PubMed ID: 19428327
[TBL] [Abstract][Full Text] [Related]
34. [Investigation on the hydroxylation metabolism of imrecoxib in vitro by using recombinant human CYPs].
Li Q; Huang HH; Dong Y; Zhong DF
Yao Xue Xue Bao; 2005 Oct; 40(10):912-5. PubMed ID: 16408808
[TBL] [Abstract][Full Text] [Related]
35. Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro.
Wang JS; DeVane CL
Drug Metab Dispos; 2003 Jun; 31(6):742-7. PubMed ID: 12756206
[TBL] [Abstract][Full Text] [Related]
36. The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study.
Bromek E; Haduch A; Daniel WA
Eur J Pharmacol; 2010 Jan; 626(2-3):171-8. PubMed ID: 19818757
[TBL] [Abstract][Full Text] [Related]
37. Sex steroid hormones differentially regulate CYP2D in female wild-type and CYP2D6-humanized mice.
Konstandi M; Andriopoulou CE; Cheng J; Gonzalez FJ
J Endocrinol; 2020 May; 245(2):301-314. PubMed ID: 32171179
[TBL] [Abstract][Full Text] [Related]
38. The interactions of a selective protein kinase C beta inhibitor with the human cytochromes P450.
Ring BJ; Gillespie JS; Binkley SN; Campanale KM; Wrighton SA
Drug Metab Dispos; 2002 Sep; 30(9):957-61. PubMed ID: 12167559
[TBL] [Abstract][Full Text] [Related]
39. Relative contributions of the five major human cytochromes P450, 1A2, 2C9, 2C19, 2D6, and 3A4, to the hepatic metabolism of the proteasome inhibitor bortezomib.
Uttamsingh V; Lu C; Miwa G; Gan LS
Drug Metab Dispos; 2005 Nov; 33(11):1723-8. PubMed ID: 16103134
[TBL] [Abstract][Full Text] [Related]
40. Oxidation of endobiotics mediated by xenobiotic-metabolizing forms of human cytochrome.
Niwa T; Murayama N; Yamazaki H
Curr Drug Metab; 2009 Sep; 10(7):700-12. PubMed ID: 19594405
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]