112 related articles for article (PubMed ID: 24374264)
1. A novel assessment of nefazodone-induced hERG inhibition by electrophysiological and stereochemical method.
Shin DS; Park MJ; Lee HA; Lee JY; Chung HC; Yoo DS; Chae CH; Park SJ; Kim KS; Bae MA
Toxicol Appl Pharmacol; 2014 Feb; 274(3):361-71. PubMed ID: 24374264
[TBL] [Abstract][Full Text] [Related]
2. Structural requirements of human ether-a-go-go-related gene channels for block by bupivacaine.
Siebrands CC; Friederich P
Anesthesiology; 2007 Mar; 106(3):523-31. PubMed ID: 17325511
[TBL] [Abstract][Full Text] [Related]
3. Ranolazine inhibition of hERG potassium channels: drug-pore interactions and reduced potency against inactivation mutants.
Du C; Zhang Y; El Harchi A; Dempsey CE; Hancox JC
J Mol Cell Cardiol; 2014 Sep; 74(100):220-30. PubMed ID: 24877995
[TBL] [Abstract][Full Text] [Related]
4. Effect of sibutramine HCl on cardiac hERG K+ channel.
Kim KS; Kim EJ; Lee HA; Park SJ
Mol Cell Biochem; 2009 Jan; 320(1-2):125-31. PubMed ID: 18781376
[TBL] [Abstract][Full Text] [Related]
5. Verapamil blocks HERG channel by the helix residue Y652 and F656 in the S6 transmembrane domain.
Duan JJ; Ma JH; Zhang PH; Wang XP; Zou AR; Tu DN
Acta Pharmacol Sin; 2007 Jul; 28(7):959-67. PubMed ID: 17588331
[TBL] [Abstract][Full Text] [Related]
6. hERG potassium channel blockade by the HCN channel inhibitor bradycardic agent ivabradine.
Melgari D; Brack KE; Zhang C; Zhang Y; El Harchi A; Mitcheson JS; Dempsey CE; Ng GA; Hancox JC
J Am Heart Assoc; 2015 Apr; 4(4):. PubMed ID: 25911606
[TBL] [Abstract][Full Text] [Related]
7. Molecular determinants of hERG potassium channel inhibition by disopyramide.
El Harchi A; Zhang YH; Hussein L; Dempsey CE; Hancox JC
J Mol Cell Cardiol; 2012 Jan; 52(1):185-95. PubMed ID: 21989164
[TBL] [Abstract][Full Text] [Related]
8. The molecular determinants of R-roscovitine block of hERG channels.
Cernuda B; Fernandes CT; Allam SM; Orzillo M; Suppa G; Chia Chang Z; Athanasopoulos D; Buraei Z
PLoS One; 2019; 14(9):e0217733. PubMed ID: 31479461
[TBL] [Abstract][Full Text] [Related]
9. Blockade of HERG K+ channel by an antihistamine drug brompheniramine requires the channel binding within the S6 residue Y652 and F656.
Park SJ; Kim KS; Kim EJ
J Appl Toxicol; 2008 Mar; 28(2):104-11. PubMed ID: 17516459
[TBL] [Abstract][Full Text] [Related]
10. Interactions between amiodarone and the hERG potassium channel pore determined with mutagenesis and in silico docking.
Zhang Y; Colenso CK; El Harchi A; Cheng H; Witchel HJ; Dempsey CE; Hancox JC
Biochem Pharmacol; 2016 Aug; 113():24-35. PubMed ID: 27256139
[TBL] [Abstract][Full Text] [Related]
11. Procaine, a state-dependent blocker, inhibits HERG channels by helix residue Y652 and F656 in the S6 transmembrane domain.
Wang N; Ma JH; Zhang PH
J Pharmacol Sci; 2013 Sep; 123(1):25-35. PubMed ID: 24005047
[TBL] [Abstract][Full Text] [Related]
12. Atypical tetracyclic antidepressant maprotiline is an antagonist at cardiac hERG potassium channels.
Kiesecker C; Alter M; Kathöfer S; Zitron E; Scholz EP; Thomas D; Kreuzer J; Katus HA; Bauer A; Karle CA
Naunyn Schmiedebergs Arch Pharmacol; 2006 Jun; 373(3):212-20. PubMed ID: 16736158
[TBL] [Abstract][Full Text] [Related]
13. Mutational analysis of block and facilitation of HERG current by a class III anti-arrhythmic agent, nifekalant.
Hosaka Y; Iwata M; Kamiya N; Yamada M; Kinoshita K; Fukunishi Y; Tsujimae K; Hibino H; Aizawa Y; Inanobe A; Nakamura H; Kurachi Y
Channels (Austin); 2007; 1(3):198-208. PubMed ID: 18690032
[TBL] [Abstract][Full Text] [Related]
14. Electrophysiological mechanisms of vandetanib-induced cardiotoxicity: Comparison of action potentials in rabbit Purkinje fibers and pluripotent stem cell-derived cardiomyocytes.
Lee HA; Hyun SA; Byun B; Chae JH; Kim KS
PLoS One; 2018; 13(4):e0195577. PubMed ID: 29630634
[TBL] [Abstract][Full Text] [Related]
15. High affinity HERG K(+) channel blockade by the antiarrhythmic agent dronedarone: resistance to mutations of the S6 residues Y652 and F656.
Ridley JM; Milnes JT; Witchel HJ; Hancox JC
Biochem Biophys Res Commun; 2004 Dec; 325(3):883-91. PubMed ID: 15541373
[TBL] [Abstract][Full Text] [Related]
16. Clemastine, a conventional antihistamine, is a high potency inhibitor of the HERG K+ channel.
Ridley JM; Milnes JT; Hancox JC; Witchel HJ
J Mol Cell Cardiol; 2006 Jan; 40(1):107-18. PubMed ID: 16288909
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of the HERG K+ channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656.
Ridley JM; Milnes JT; Duncan RS; McPate MJ; James AF; Witchel HJ; Hancox JC
FEBS Lett; 2006 Apr; 580(8):1999-2005. PubMed ID: 16542653
[TBL] [Abstract][Full Text] [Related]
18. Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole.
Gualdani R; Cavalluzzi MM; Tadini-Buoninsegni F; Convertino M; Gailly P; Stary-Weinzinger A; Lentini G
Cell Physiol Biochem; 2018; 45(6):2233-2245. PubMed ID: 29550817
[TBL] [Abstract][Full Text] [Related]
19. Block effect of capsaicin on hERG potassium currents is enhanced by S6 mutation at Y652.
Xing J; Ma J; Zhang P; Fan X
Eur J Pharmacol; 2010 Mar; 630(1-3):1-9. PubMed ID: 19903464
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action.
Thomas D; Hammerling BC; Wu K; Wimmer AB; Ficker EK; Kirsch GE; Kochan MC; Wible BA; Scholz EP; Zitron E; Kathöfer S; Kreye VA; Katus HA; Schoels W; Karle CA; Kiehn J
Br J Pharmacol; 2004 Jun; 142(3):485-94. PubMed ID: 15148258
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
