BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 24375753)

  • 1. Sex Is a major determinant of neuronal dysfunction in neurofibromatosis type 1.
    Diggs-Andrews KA; Brown JA; Gianino SM; Rubin JB; Wozniak DF; Gutmann DH
    Ann Neurol; 2014 Feb; 75(2):309-16. PubMed ID: 24375753
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NF1 germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1.
    Toonen JA; Anastasaki C; Smithson LJ; Gianino SM; Li K; Kesterson RA; Gutmann DH
    Hum Mol Genet; 2016 May; 25(9):1703-13. PubMed ID: 26908603
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reduced striatal dopamine underlies the attention system dysfunction in neurofibromatosis-1 mutant mice.
    Brown JA; Emnett RJ; White CR; Yuede CM; Conyers SB; O'Malley KL; Wozniak DF; Gutmann DH
    Hum Mol Genet; 2010 Nov; 19(22):4515-28. PubMed ID: 20826448
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Elucidating the impact of neurofibromatosis-1 germline mutations on neurofibromin function and dopamine-based learning.
    Anastasaki C; Woo AS; Messiaen LM; Gutmann DH
    Hum Mol Genet; 2015 Jun; 24(12):3518-28. PubMed ID: 25788518
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma-induced retinal pathology.
    Toonen JA; Solga AC; Ma Y; Gutmann DH
    J Exp Med; 2017 Jan; 214(1):17-25. PubMed ID: 27923908
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dopamine deficiency underlies learning deficits in neurofibromatosis-1 mice.
    Diggs-Andrews KA; Tokuda K; Izumi Y; Zorumski CF; Wozniak DF; Gutmann DH
    Ann Neurol; 2013 Feb; 73(2):309-15. PubMed ID: 23225063
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Defective cAMP generation underlies the sensitivity of CNS neurons to neurofibromatosis-1 heterozygosity.
    Brown JA; Gianino SM; Gutmann DH
    J Neurosci; 2010 Apr; 30(16):5579-89. PubMed ID: 20410111
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Optic nerve dysfunction in a mouse model of neurofibromatosis-1 optic glioma.
    Hegedus B; Hughes FW; Garbow JR; Gianino S; Banerjee D; Kim K; Ellisman MH; Brantley MA; Gutmann DH
    J Neuropathol Exp Neurol; 2009 May; 68(5):542-51. PubMed ID: 19525901
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insights into optic pathway glioma vision loss from mouse models of neurofibromatosis type 1.
    Freret ME; Gutmann DH
    J Neurosci Res; 2019 Jan; 97(1):45-56. PubMed ID: 29704429
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NG2-cells are not the cell of origin for murine neurofibromatosis-1 (Nf1) optic glioma.
    Solga AC; Gianino SM; Gutmann DH
    Oncogene; 2014 Jan; 33(3):289-99. PubMed ID: 23318450
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1.
    Warrington NM; Woerner BM; Daginakatte GC; Dasgupta B; Perry A; Gutmann DH; Rubin JB
    Cancer Res; 2007 Sep; 67(18):8588-95. PubMed ID: 17875698
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neurofibromatosis-1 heterozygosity impairs CNS neuronal morphology in a cAMP/PKA/ROCK-dependent manner.
    Brown JA; Diggs-Andrews KA; Gianino SM; Gutmann DH
    Mol Cell Neurosci; 2012 Jan; 49(1):13-22. PubMed ID: 21903164
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation.
    Daginakatte GC; Gianino SM; Zhao NW; Parsadanian AS; Gutmann DH
    Cancer Res; 2008 Dec; 68(24):10358-66. PubMed ID: 19074905
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neurofibromatosis type 1-associated optic pathway gliomas: pathogenesis and emerging treatments.
    Amato A; Imbimbo BP; Falsini B
    Eur Rev Med Pharmacol Sci; 2023 Jun; 27(12):5636-5653. PubMed ID: 37401302
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The impact of coexisting genetic mutations on murine optic glioma biology.
    Kaul A; Toonen JA; Gianino SM; Gutmann DH
    Neuro Oncol; 2015 May; 17(5):670-7. PubMed ID: 25246427
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Defining the temporal course of murine neurofibromatosis-1 optic gliomagenesis reveals a therapeutic window to attenuate retinal dysfunction.
    Toonen JA; Ma Y; Gutmann DH
    Neuro Oncol; 2017 Jun; 19(6):808-819. PubMed ID: 28039362
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ultrastructural characterization of the optic pathway in a mouse model of neurofibromatosis-1 optic glioma.
    Kim KY; Ju WK; Hegedus B; Gutmann DH; Ellisman MH
    Neuroscience; 2010 Sep; 170(1):178-88. PubMed ID: 20600672
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Akt- or MEK-mediated mTOR inhibition suppresses Nf1 optic glioma growth.
    Kaul A; Toonen JA; Cimino PJ; Gianino SM; Gutmann DH
    Neuro Oncol; 2015 Jun; 17(6):843-53. PubMed ID: 25534823
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Optic glioma and precocious puberty in a girl with neurofibromatosis type 1 carrying an R681X mutation of NF1: case report and review of the literature.
    Kocova M; Kochova E; Sukarova-Angelovska E
    BMC Endocr Disord; 2015 Dec; 15():82. PubMed ID: 26666878
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging.
    Su W; Xing R; Guha A; Gutmann DH; Sherman LS
    Glia; 2007 May; 55(7):723-33. PubMed ID: 17348023
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.