BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 24376889)

  • 1. Effects of inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate induced insulin resistance in L6 myotubes.
    Mikłosz A; Łukaszuk B; Baranowski M; Górski J; Chabowski A
    PLoS One; 2013; 8(12):e85547. PubMed ID: 24376889
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells.
    Watson ML; Coghlan M; Hundal HS
    Biochem J; 2009 Feb; 417(3):791-801. PubMed ID: 18922131
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation.
    Perdomo G; Commerford SR; Richard AM; Adams SH; Corkey BE; O'Doherty RM; Brown NF
    J Biol Chem; 2004 Jun; 279(26):27177-86. PubMed ID: 15105415
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
    Gorshkova I; Zhou T; Mathew B; Jacobson JR; Takekoshi D; Bhattacharya P; Smith B; Aydogan B; Weichselbaum RR; Natarajan V; Garcia JG; Berdyshev EV
    J Lipid Res; 2012 Aug; 53(8):1553-68. PubMed ID: 22615416
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Downregulation of lipin-1 induces insulin resistance by increasing intracellular ceramide accumulation in C2C12 myotubes.
    Huang S; Huang S; Wang X; Zhang Q; Liu J; Leng Y
    Int J Biol Sci; 2017; 13(1):1-12. PubMed ID: 28123341
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells.
    Powell DJ; Turban S; Gray A; Hajduch E; Hundal HS
    Biochem J; 2004 Sep; 382(Pt 2):619-29. PubMed ID: 15193147
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oleate protects against palmitate-induced insulin resistance in L6 myotubes.
    Gao D; Griffiths HR; Bailey CJ
    Br J Nutr; 2009 Dec; 102(11):1557-63. PubMed ID: 19622194
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance.
    Turpin SM; Lancaster GI; Darby I; Febbraio MA; Watt MJ
    Am J Physiol Endocrinol Metab; 2006 Dec; 291(6):E1341-50. PubMed ID: 16849630
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Myriocin treatment affects lipid metabolism in skeletal muscles of rats with streptozotocin-induced type 1 diabetes.
    Kurek K; Garbowska M; Ziembicka DM; Łukaszuk B; Rogowski J; Chabowski A; Górski J; Żendzian-Piotrowska M
    Adv Med Sci; 2017 Mar; 62(1):65-73. PubMed ID: 28189121
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin-stimulated Rac1-GTP binding is not impaired by palmitate treatment in L6 myotubes.
    Stierwalt HD; Ehrlicher SE; Bergman BC; Robinson MM; Newsom SA
    Physiol Rep; 2018 Dec; 6(24):e13956. PubMed ID: 30592185
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity.
    Hu W; Bielawski J; Samad F; Merrill AH; Cowart LA
    J Lipid Res; 2009 Sep; 50(9):1852-62. PubMed ID: 19369694
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle.
    Radin MS; Sinha S; Bhatt BA; Dedousis N; O'Doherty RM
    Diabetologia; 2008 Feb; 51(2):336-46. PubMed ID: 18060381
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ceramide accumulation in L6 skeletal muscle cells due to increased activity of ceramide synthase isoforms has opposing effects on insulin action to those caused by palmitate treatment.
    Frangioudakis G; Diakanastasis B; Liao BQ; Saville JT; Hoffman NJ; Mitchell TW; Schmitz-Peiffer C
    Diabetologia; 2013 Dec; 56(12):2697-701. PubMed ID: 23989724
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fenofibrate Reverses Palmitate Induced Impairment in Glucose Uptake in Skeletal Muscle Cells by Preventing Cytosolic Ceramide Accumulation.
    Bhattacharjee S; Das N; Mandala A; Mukhopadhyay S; Roy SS
    Cell Physiol Biochem; 2015; 37(4):1315-28. PubMed ID: 26488284
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sphingolipid changes do not underlie fatty acid-evoked GLUT4 insulin resistance nor inflammation signals in muscle cells.
    Pillon NJ; Frendo-Cumbo S; Jacobson MR; Liu Z; Milligan PL; Hoang Bui H; Zierath JR; Bilan PJ; Brozinick JT; Klip A
    J Lipid Res; 2018 Jul; 59(7):1148-1163. PubMed ID: 29794037
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption.
    Ussher JR; Koves TR; Cadete VJ; Zhang L; Jaswal JS; Swyrd SJ; Lopaschuk DG; Proctor SD; Keung W; Muoio DM; Lopaschuk GD
    Diabetes; 2010 Oct; 59(10):2453-64. PubMed ID: 20522596
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high-fat diet-fed mice.
    Bruce CR; Risis S; Babb JR; Yang C; Kowalski GM; Selathurai A; Lee-Young RS; Weir JM; Yoshioka K; Takuwa Y; Meikle PJ; Pitson SM; Febbraio MA
    Diabetes; 2012 Dec; 61(12):3148-55. PubMed ID: 22961081
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.
    Lee JS; Pinnamaneni SK; Eo SJ; Cho IH; Pyo JH; Kim CK; Sinclair AJ; Febbraio MA; Watt MJ
    J Appl Physiol (1985); 2006 May; 100(5):1467-74. PubMed ID: 16357064
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance.
    Ussher JR; Folmes CD; Keung W; Fillmore N; Jaswal JS; Cadete VJ; Beker DL; Lam VH; Zhang L; Lopaschuk GD
    PLoS One; 2012; 7(5):e37703. PubMed ID: 22629445
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro palmitate treatment of myotubes from postmenopausal women leads to ceramide accumulation, inflammation and affected insulin signaling.
    Abildgaard J; Henstridge DC; Pedersen AT; Langley KG; Scheele C; Pedersen BK; Lindegaard B
    PLoS One; 2014; 9(7):e101555. PubMed ID: 25000528
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.