BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 24379264)

  • 1. [Classical oxazaphosphorines--metabolism and therapeutic properties--new implications].
    Sloderbach A; Górska A; Sikorska M; Misiura K; Hładoń B
    Postepy Hig Med Dosw (Online); 2013 Dec; 67():1235-53. PubMed ID: 24379264
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism and transport of oxazaphosphorines and the clinical implications.
    Zhang J; Tian Q; Yung Chan S; Chuen Li S; Zhou S; Duan W; Zhu YZ
    Drug Metab Rev; 2005; 37(4):611-703. PubMed ID: 16393888
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxazaphosphorines: new therapeutic strategies for an old class of drugs.
    Giraud B; Hebert G; Deroussent A; Veal GJ; Vassal G; Paci A
    Expert Opin Drug Metab Toxicol; 2010 Aug; 6(8):919-38. PubMed ID: 20446865
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Primary breast tumor levels of suspected molecular determinants of cellular sensitivity to cyclophosphamide, ifosfamide, and certain other anticancer agents as predictors of paired metastatic tumor levels of these determinants. Rational individualization of cancer chemotherapeutic regimens.
    Sreerama L; Sládek NE
    Cancer Chemother Pharmacol; 2001 Mar; 47(3):255-62. PubMed ID: 11320670
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects.
    Delahousse J; Skarbek C; Desbois M; Perfettini JL; Chaput N; Paci A
    J Immunother Cancer; 2020 Aug; 8(2):. PubMed ID: 32784216
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vivo modulation of alternative pathways of P-450-catalyzed cyclophosphamide metabolism: impact on pharmacokinetics and antitumor activity.
    Yu LJ; Drewes P; Gustafsson K; Brain EG; Hecht JE; Waxman DJ
    J Pharmacol Exp Ther; 1999 Mar; 288(3):928-37. PubMed ID: 10027828
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trofosfamide metabolism in different species--ifosfamide is the predominant metabolite.
    Boos J; Küpker F; Blaschke G; Jürgens H
    Cancer Chemother Pharmacol; 1993; 33(1):71-6. PubMed ID: 8269592
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intratumoral activation and enhanced chemotherapeutic effect of oxazaphosphorines following cytochrome P-450 gene transfer: development of a combined chemotherapy/cancer gene therapy strategy.
    Chen L; Waxman DJ
    Cancer Res; 1995 Feb; 55(3):581-9. PubMed ID: 7834628
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the anticancer drugs cyclophosphamide and ifosfamide by cytochrome P450 BM3 mutants.
    Vredenburg G; den Braver-Sewradj S; van Vugt-Lussenburg BM; Vermeulen NP; Commandeur JN; Vos JC
    Toxicol Lett; 2015 Jan; 232(1):182-92. PubMed ID: 25448283
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of cytochrome P450 in oxazaphosphorine metabolism. Deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochromes P450.
    Yu L; Waxman DJ
    Drug Metab Dispos; 1996 Nov; 24(11):1254-62. PubMed ID: 8937861
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines.
    Chang TK; Yu L; Maurel P; Waxman DJ
    Cancer Res; 1997 May; 57(10):1946-54. PubMed ID: 9157990
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acrolein and chloroacetaldehyde: an examination of the cell and cell-free biomarkers of toxicity.
    MacAllister SL; Martin-Brisac N; Lau V; Yang K; O'Brien PJ
    Chem Biol Interact; 2013 Feb; 202(1-3):259-66. PubMed ID: 23220588
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.
    Skarbek C; Lesueur LL; Chapuis H; Deroussent A; Pioche Durieu C; Daville A; Caron J; Rivard M; Martens T; Bertrand JR; Le Cam E; Vassal G; Couvreur P; Desmaele D; Paci A
    J Med Chem; 2015 Jan; 58(2):705-17. PubMed ID: 25494842
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cyclophosphamide modulates rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase activity and messenger RNA levels through the combined action of acrolein and phosphoramide mustard.
    Chang TK; Waxman DJ
    Cancer Res; 1993 Jun; 53(11):2490-7. PubMed ID: 8495410
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Excretion kinetics of ifosfamide side-chain metabolites in children on continuous and short-term infusion.
    Silies H; Blaschke G; Hohenlöchter B; Rossi R; Jürgens H; Boos J
    Int J Clin Pharmacol Ther; 1998 May; 36(5):246-52. PubMed ID: 9629987
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione.
    Dirven HA; van Ommen B; van Bladeren PJ
    Cancer Res; 1994 Dec; 54(23):6215-20. PubMed ID: 7954469
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes.
    Chang TK; Weber GF; Crespi CL; Waxman DJ
    Cancer Res; 1993 Dec; 53(23):5629-37. PubMed ID: 8242617
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ifosfamide metabolites CAA, 4-OH-Ifo and Ifo-mustard reduce apical phosphate transport by changing NaPi-IIa in OK cells.
    Patzer L; Hernando N; Ziegler U; Beck-Schimmer B; Biber J; Murer H
    Kidney Int; 2006 Nov; 70(10):1725-34. PubMed ID: 17003823
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the anticancer prodrugs cyclophosphamide and ifosfamide: identification of cytochrome P450 2B enzymes and site-specific mutants with improved enzyme kinetics.
    Chen CS; Lin JT; Goss KA; He YA; Halpert JR; Waxman DJ
    Mol Pharmacol; 2004 May; 65(5):1278-85. PubMed ID: 15102956
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stem cell toxicity of oxazaphosphorine metabolites in comparison to their antileukemic activity.
    Brueggemann SK; Schlenke P; Klich S; Deeken M; Peters SO; Wagner T
    Biochem Pharmacol; 2002 Apr; 63(7):1337-41. PubMed ID: 11960610
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.