BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

511 related articles for article (PubMed ID: 24384723)

  • 1. HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer.
    Schulz R; Streller F; Scheel AH; Rüschoff J; Reinert MC; Dobbelstein M; Marchenko ND; Moll UM
    Cell Death Dis; 2014 Jan; 5(1):e980. PubMed ID: 24384723
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression.
    Schulz R; Marchenko ND; Holembowski L; Fingerle-Rowson G; Pesic M; Zender L; Dobbelstein M; Moll UM
    J Exp Med; 2012 Feb; 209(2):275-89. PubMed ID: 22271573
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heat shock factor 1 confers resistance to lapatinib in ERBB2-positive breast cancer cells.
    Yallowitz A; Ghaleb A; Garcia L; Alexandrova EM; Marchenko N
    Cell Death Dis; 2018 May; 9(6):621. PubMed ID: 29799521
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A gain-of-function mutant p53-HSF1 feed forward circuit governs adaptation of cancer cells to proteotoxic stress.
    Li D; Yallowitz A; Ozog L; Marchenko N
    Cell Death Dis; 2014 Apr; 5(4):e1194. PubMed ID: 24763051
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heat shock factor Hsf1 cooperates with ErbB2 (Her2/Neu) protein to promote mammary tumorigenesis and metastasis.
    Xi C; Hu Y; Buckhaults P; Moskophidis D; Mivechi NF
    J Biol Chem; 2012 Oct; 287(42):35646-35657. PubMed ID: 22847003
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel Hsp90 inhibitor FW-04-806 displays potent antitumor effects in HER2-positive breast cancer cells as a single agent or in combination with lapatinib.
    Huang W; Wu QD; Zhang M; Kong YL; Cao PR; Zheng W; Xu JH; Ye M
    Cancer Lett; 2015 Jan; 356(2 Pt B):862-71. PubMed ID: 25449780
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer.
    Klemke L; De Oliveira T; Witt D; Winkler N; Bohnenberger H; Bucala R; Conradi LC; Schulz-Heddergott R
    Cell Death Dis; 2021 Feb; 12(2):155. PubMed ID: 33542244
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer.
    Cheng Q; Chang JT; Geradts J; Neckers LM; Haystead T; Spector NL; Lyerly HK
    Breast Cancer Res; 2012 Apr; 14(2):R62. PubMed ID: 22510516
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth.
    Zhao YH; Zhou M; Liu H; Ding Y; Khong HT; Yu D; Fodstad O; Tan M
    Oncogene; 2009 Oct; 28(42):3689-701. PubMed ID: 19668225
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular stress-inducing compounds increase osteoclast formation in a heat shock factor 1 protein-dependent manner.
    Chai RC; Kouspou MM; Lang BJ; Nguyen CH; van der Kraan AG; Vieusseux JL; Lim RC; Gillespie MT; Benjamin IJ; Quinn JM; Price JT
    J Biol Chem; 2014 May; 289(19):13602-14. PubMed ID: 24692538
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia.
    Ganguly S; Home T; Yacoub A; Kambhampati S; Shi H; Dandawate P; Padhye S; Saluja AK; McGuirk J; Rao R
    Oncotarget; 2015 Oct; 6(31):31767-79. PubMed ID: 26397138
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis.
    Meng L; Gabai VL; Sherman MY
    Oncogene; 2010 Sep; 29(37):5204-13. PubMed ID: 20622894
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insights from yeast into whether the inhibition of heat shock transcription factor (Hsf1) by rapamycin can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor.
    Millson SH; Piper PW
    Oncotarget; 2014 Jul; 5(13):5054-64. PubMed ID: 24970820
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intrinsic proteotoxic stress levels vary and act as a predictive marker for sensitivity of cancer cells to Hsp90 inhibition.
    Pastorek M; Muller P; Coates PJ; Vojtesek B
    PLoS One; 2018; 13(8):e0202758. PubMed ID: 30138434
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity.
    Truman AW; Millson SH; Nuttall JM; Mollapour M; Prodromou C; Piper PW
    Eukaryot Cell; 2007 Apr; 6(4):744-52. PubMed ID: 17293484
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ganetespib targets multiple levels of the receptor tyrosine kinase signaling cascade and preferentially inhibits ErbB2-overexpressing breast cancer cells.
    Lee H; Saini N; Howard EW; Parris AB; Ma Z; Zhao Q; Zhao M; Liu B; Edgerton SM; Thor AD; Yang X
    Sci Rep; 2018 May; 8(1):6829. PubMed ID: 29717218
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of mixed lineage leukemia 1(MLL1) protein as a coactivator of heat shock factor 1(HSF1) protein in response to heat shock protein 90 (HSP90) inhibition.
    Chen Y; Chen J; Yu J; Yang G; Temple E; Harbinski F; Gao H; Wilson C; Pagliarini R; Zhou W
    J Biol Chem; 2014 Jul; 289(27):18914-27. PubMed ID: 24831003
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting HSF1 sensitizes cancer cells to HSP90 inhibition.
    Chen Y; Chen J; Loo A; Jaeger S; Bagdasarian L; Yu J; Chung F; Korn J; Ruddy D; Guo R; McLaughlin ME; Feng F; Zhu P; Stegmeier F; Pagliarini R; Porter D; Zhou W
    Oncotarget; 2013 Jun; 4(6):816-29. PubMed ID: 23615731
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers.
    Raja SM; Clubb RJ; Ortega-Cava C; Williams SH; Bailey TA; Duan L; Zhao X; Reddi AL; Nyong AM; Natarajan A; Band V; Band H
    Cancer Biol Ther; 2011 Jan; 11(2):263-76. PubMed ID: 21088503
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivo.
    Hu Y; Mivechi NF
    J Biol Chem; 2003 May; 278(19):17299-306. PubMed ID: 12621024
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.